Enhanced VWF biosynthesis and elevated plasma VWF due to a natural variant in the murine Vwf gene
Abstract Both genetic and environmental influences contribute to the wide variation in plasma von Willebrand factor (VWF) levels observed in humans. Inbred mouse strains also have highly variable plasma VWF levels, providing a convenient model in which to study genetic modifiers of VWF.
Jeffrey C. Long+5 more
openaire +4 more sources
Levels of von Willebrand factor antigen and von Willebrand factor cleaving protease (ADAMTS13) activity predict clinical events in chronic heart failure. [PDF]
Decreased activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease, was recently reported in cardiovascular diseases and in hepatic failure.
Borgulya, Gábor+10 more
core +1 more source
Application of microfluidic devices in studies of thrombosis and hemostasis
Due to the importance of fluid flow during thrombotic episodes, it is quite appropriate to study clotting and bleeding processes in devices that have well-defined fluid shear environments.
Changjie Zhang, Sriram Neelamegham
doaj +1 more source
Wind field and sex constrain the flight speeds of central-place foraging albatrosses [PDF]
By extracting energy from the highly dynamic wind and wave fields that typify pelagic habitats, albatrosses are able to proceed almost exclusively by gliding flight.
Akira Fukuda+12 more
core +1 more source
Circulating inflammatory and hemostatic biomarkers are associated with risk of myocardial infarction and coronary death, but not angina pectoris, in older men [PDF]
Aims: The extent to which hemostatic and inflammatory biomarkers are related to angina pectoris as compared with myocardial infarction (MI) remains uncertain.
Lennon, L+5 more
core +1 more source
The Level of vWF Antigen and Coagulation Markers in Hospitalized Patients with Covid-19
Hadeel Al Otair,1 Khalid AlSaleh,2 Fatmah S AlQahtany,3 Khalid Al Ayed,1 Hessah Al Ammar,4 Noura Al Mefgai,4 Faisal Al Zeer5 1Department of Medicine, King Saud University Medical city (KSUMC), King Saud University, Riyadh, Saudi Arabia; 2Department of ...
Al Otair H+6 more
doaj
Finite VEVs from a Large Distance Vacuum Wave Functional [PDF]
We show how to compute vacuum expectation values from derivative expansions of the vacuum wave functional. Such expansions appear to be valid only for slowly varying fields, but by exploiting analyticity in a complex scale parameter we can reconstruct ...
ALFONSO JARAMILLO+5 more
core +2 more sources
Utility of microfluidic devices to study the platelet–endothelium interface
The integration of biomaterials and understanding of vascular biology has led to the development of perfusable endothelialized flow models, which have been used as valuable tools to study the platelet–endothelium interface under shear.
Jevgenia Zilberman-Rudenko+6 more
doaj +1 more source
Complex changes in von Willebrand factor-associated parameters are acquired during uncomplicated pregnancy. [PDF]
BACKGROUND:The coagulation protein von Willebrand Factor (VWF) is known to be elevated in pregnancy. However, the timing and nature of changes in VWF and associated parameters throughout pregnancy are not well understood.
Danielle N Drury-Stewart+7 more
doaj +1 more source
Endothelial Cells Expressing Endothelial and Mesenchymal Cell Gene Products in Lung Tissue From Patients With Systemic Sclerosis-Associated Interstitial Lung Disease. [PDF]
OBJECTIVE: To examine whether lung endothelial cells (ECs) from patients with systemic sclerosis (SSc)-associated interstitial lung disease (ILD) express mesenchymal cell-specific proteins and gene transcripts, indicative of the occurrence of endothelial-
Arciniegas+41 more
core +2 more sources