Results 91 to 100 of about 27,703 (234)

The Minimal Nonplanar Strong Digraphs

Journal of Graph Theory, EarlyView.
ABSTRACT Kuratowski's theorem says that the minimal (under subgraph containment) graphs that are not planar are the subdivisions of K 5 ${K}_{5}$ and of K 3 , 3 ${K}_{3,3}$. Here we study the minimal (under subdigraph containment) strongly‐connected digraphs that are not planar.
Stephen Bartell, Paul Seymour
wiley   +1 more source

Verruciform xanthoma of buccal mucosa: A case report with review of literature

Contemporary Clinical Dentistry, 2012
Verruciformxanthoma (VX) is an uncommon benign mucocutaneous lesion of unknown etiology. It appears as a papule or single plaque with verrucous or papillomatous surface and variable color from reddish pink to gray.
Sudhir Bhalerao, Pooja Bhat, Ranit Chhabra, Avinash Tamgadge   +3 more
doaj   +1 more source

Identification of the binding sites of the modulators of the CFTR channel : corrector VX-809 and potentiator VX-770

, 2020
La mucoviscidose est une maladie génétique létale causée par des mutations du gène CFTR. Les mutations les plus fréquentes altèrent le repliement de la protéine (ex : F508del) ou sa fonction (ex : G551D).
Baatallah, Nesrine
core  

Extraction of Nerve Agent VX from Soils

, 2016
The development and optimization of a method allowing the extraction of intact organophosphorus chemical warfare agent O-ethyl S-(2-diisopropylaminoethyl) methylphosphonothiolate (VX) from several types of soils are presented here.
Cécile Montauban (2717539), Bruno Bellier (2717533), Arlette Bégos (2717536)   +2 more
core   +1 more source

Flow‐Critical Graphs

Journal of Graph Theory, EarlyView.
ABSTRACT Lovász et al. proved that every six‐edge‐connected graph has a nowhere‐zero three‐flow. In fact, they proved a more technical statement, which says that there exists a nowhere‐zero three‐flow that extends the flow prescribed on the incident edges of a single vertex z $z$ with bounded degree. We extend this theorem of Lovász et al.
Arnbjörg Soffía Árnadóttir, Zdeněk Dvořák, Bernard Lidický, Benjamin Moore, Evelyne Smith‐Roberge, Robert Šámal   +5 more
wiley   +1 more source

Deep mutational scanning data for VX-661 and VX-445 response colored by AlphaMissense pathogenicity score.

A. Basal CFTR surface immune staining versus VX-661 CFTR cell surface immune staining intensity [23]. Pathogenic variants score from 0.56–1.00 (violet), ambiguous variants score from 0.34–0.56 (grey), and benign variants score 0.04–0.34 (green).
Jonathan P. Schlebach (1326678), Kathryn E. Oliver (17847260), Lars Plate (1265706), Jens Meiler (112401), Eli Fritz McDonald (7382066)   +4 more
core   +1 more source

State-Dependent Inhibition of Nav1.8 Sodium Channels by VX-150 and VX-548

Molecular Pharmacology
Nav1.8 sodium channels (Nav1.8) are an attractive therapeutic target for pain because they are prominent in primary pain-sensing neurons with little expression in most other kinds of neurons. Recently, two Nav1.8-targeted compounds, VX-150 and VX-548, have shown efficacy in clinical trials for reducing pain.
Patric Vaelli, Akie Fujita, Sooyeon Jo, Han-Xiong Bear Zhang, Tomás Osorno, Xiao Ma, Bruce P. Bean   +6 more
openaire   +2 more sources

Assessment of Glucose Metabolism in Vivo in the Human Frontal Lobe Using Interleaved 1H and 13C MRS at 7T

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background 13C magnetic resonance spectroscopy (MRS), combined with 13C‐labeled substrate infusion, offers a nonionizing, minimally invasive method for assessing fluxes through the main cerebral energy metabolism pathways. However, its human application at 7T has not been fully established, especially within the frontal lobe, where alterations
Ying Xiao, Daniel Wenz, Indrit Bègue, Patric Hagmann, João M. N. Duarte, Loan Mattera, Nathalie Philippe, Antonia Kaiser, Katarzyna Pierzchala, André Döring, Mark Widmaier, Kim Q. Do, Rolf Gruetter, Dimitrios C. Karampinos, Lijing Xin   +14 more
wiley   +1 more source

Inhibition of mitotic kinase Aurora suppresses Akt-1 activation and induces apoptotic cell death in all-trans retinoid acid-resistant acute promyelocytic leukemia cells

Journal of Translational Medicine, 2011
Background Aurora kinase ensures accurate chromosome segregation during cell cycle, maintaining genetic integrity in cell division. VX-680, a small-molecule Aurora kinase inhibitor, interferes with mitotic entry and formation of bipolar spindles.
Long Zi-Jie, Huang Shan, Xu Duo-Rong, Chen Jia-Jie, Zou Zheng-Zhi, Li Juan, Lin Dong-Jun, Liu Quentin   +7 more
doaj   +1 more source

Graded Differential Polynomial Rings

Mathematische Nachrichten, EarlyView.
ABSTRACT We study differential polynomial rings R[t;δ]$R[t;\delta]$ over Γ$\Gamma$‐graded rings, where Γ$\Gamma$ is an arbitrary group. We show that R[t;δ]$R[t;\delta]$ admits a Γ$\Gamma$‐grading compatible with that of R$R$ if and only if δ$\delta$ is a γ$\gamma$‐derivation for some γ∈CΓ(ΓR)$\gamma \in C_\Gamma (\Gamma _R)$, and that this grading is ...
Yassine Ait Mohamed
wiley   +1 more source