Results 61 to 70 of about 252,763 (309)

Concurrent validity and reliability of a low-cost gait analysis system for assessment of spatiotemporal gait parameters

open access: yesJournal of Rehabilitation Medicine, 2019
Objective: To determine the concurrent validity and reliability of a low-cost spatiotemporal gait analysis system for clinical use in rehabilitation medicine. Design: Cross-sectional study. Subjects: Thirty-three healthy adults.
Maijke van Bloemendaal   +5 more
doaj   +1 more source

Optimal Source Tracking and Beaming of LISA [PDF]

open access: yes, 2006
We revisit the directionally optimal data streams of LISA first introduced in Nayak etal. It was shown that by using appropriate choice of Time delay interferometric (TDI) combinations, a monochromatic fixed source in the barycentric frame can be ...
Pai, Archana
core   +3 more sources

Direct Binding of the Corrector VX-809 to Human CFTR NBD1: Evidence of an Allosteric Coupling between the Binding Site and the NBD1:CL4 Interface [PDF]

open access: hybridMolecular Pharmacology, 2017
Rhea P. Hudson   +7 more
openalex   +2 more sources

VX‐809 mitigates disease in a mouse model of autosomal dominant polycystic kidney disease bearing the R3277C human mutation

open access: yesThe FASEB Journal, 2021
Autosomal dominant polycystic kidney disease (ADPKD) is associated with the formation of renal cysts. We have devised a therapeutic approach, based on reversing the cyst phenotype from secretion to absorption by using VX‐809, a modulator of the cystic ...
M. Yanda, L. Cebotaru
semanticscholar   +1 more source

Clinical activity of a htert (vx-001) cancer vaccine as post-chemotherapy maintenance immunotherapy in patients with stage IV non-small cell lung cancer: final results of a randomised phase 2 clinical trial

open access: yesBritish Journal of Cancer, 2020
Background The cancer vaccine Vx-001, which targets the universal tumour antigen TElomerase Reverse Transcriptase (TERT), can mount specific Vx-001/TERT 572 CD8 + cytotoxic T cells; this immune response is associated with improved overall survival (OS ...
C. Gridelli   +25 more
semanticscholar   +1 more source

A double T‐type H‐bridge reduced switch multilevel inverter for a wide range of DC voltage variations

open access: yesIET Power Electronics, EarlyView., 2023
This paper proposes a new Double T‐type H‐bridge (DTH) module configuration that can produce 9, 13, 17, 19, 21, and 25 levels using reduced components. Abstract Renewable energy sources are subject to input source uncertainties, which can negatively impact output voltage THD.
Omid Zolfagharian   +2 more
wiley   +1 more source

Vaccination with staphylococcal protein A protects mice against systemic complications of skin infection recurrences

open access: yesFrontiers in Immunology
Skin and soft tissue infections (SSTIs) are the most common diseases caused by Staphylococcus aureus (S. aureus), which can progress to threatening conditions due to recurrences and systemic complications.
Andrea Paola Mandelli   +9 more
doaj   +1 more source

Mesoscopic Kinetic Basis of Macroscopic Chemical Thermodynamics: A Mathematical Theory

open access: yes, 2016
From a mathematical model that describes a complex chemical kinetic system of $N$ species and $M$ elementrary reactions in a rapidly stirred vessel of size $V$ as a Markov process, we show that a macroscopic chemical thermodynamics emerges as $V ...
Ge, Hao, Qian, Hong
core   +1 more source

Nerve agents: A clear and present danger to mankind [PDF]

open access: yesScripta Medica, 2019
This editorial is written on the occasion of the 25th anniversary of the infamous sarin and VX terrorist attacks in Japan, in order to increase the awareness of the potential terrorist use of nerve agents and to urge the preparedness to cope with its ...
Stojiljković Miloš P.
doaj  

VX-765 attenuates silica-induced lung inflammatory injury and fibrosis by modulating alveolar macrophages pyroptosis in mice

open access: yesEcotoxicology and Environmental Safety, 2023
Silicosis is a diffuse fibrotic lung disease in which excessive inflammatory responses are triggered by silica exposure. Pyroptosis, a pro-inflammatory mode of programmed cell death, is mediated by gasdermin and may play a pivotal role in the development
Huihui Tao   +14 more
doaj   +1 more source

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