Results 111 to 120 of about 108,453 (351)
Host-Directed Therapy in Tuberculosis: Targeting Host Metabolism
Frontiers in Immunology, 2020 Mycobacterium tuberculosis (Mtb) has complex and intricate interactions with host immune cells. Mtb can survive, persist, and grow within macrophages and thereby circumvent detection by the innate immune system.
Jae-Sung Kim +5 more
doaj +1 more source
Notch stimulates growth by direct regulation of genes involved in the control of glycolysis and the tricarboxylic acid cycle. [PDF]
, 2016 Glycolytic shift is a characteristic feature of rapidly proliferating cells, such as cells during development and during immune response or cancer cells, as well as of stem cells.
Bray, Sarah J +6 more
core +1 more source
International Journal of Trends in OncoScienceThe Warburg effect, defined by cancer cells’ preference for aerobic glycolysis over mitochondrial oxidative phosphorylation for energy production, has been a central topic in cancer research since its identification in 1924. This process involves elevated glucose uptake and lactate production, even in the presence of oxygen, supporting rapid cell ...
Dr. T. Shehnaz Begum +6 more
openaire +1 more source
Electrically Readable Lateral Flow Assay Using Organic Transistors for Diagnostic Applications
Advanced Materials, EarlyView.Electrolyte‐gated organic field‐effect transistors (EGOFETs) are integrated with lateral flow (LF) paper fluidics to create a reusable, portable, and low‐cost point‐of‐care (PoC) diagnostic test. The devices are validated for Human Immunoglobulin G detection, achieving high sensitivity (0.1 fm), selectivity, and reproducibility with rapid results in 20–
María Jesús Ortiz‐Aguayo +4 more
wiley +1 more source
Advanced Materials Interfaces, EarlyView.Interfacial charge transfer and low‐resistance interphase formation between PEO‐based polymer and Li10GeP2S12 solid electrolytes are investigated using multi‐electrode impedance spectroscopy and advanced analytical techniques such as XPS and ToF‐SIMS.
Ujjawal Sigar +6 more
wiley +1 more source
Macromolecular crowding explains overflow metabolism in cells [PDF]
, 2016 Overflow metabolism is a metabolic phenotype of cells characterized by mixed oxidative phosphorylation (OxPhos) and fermentative glycolysis in the presence of oxygen.
Oltvai, Zoltán N., Vazquez, Alexei
core +1 more source
Advanced Materials Interfaces, EarlyView.Conductive silk‐polypyrrole scaffolds couple redox stability with cell‐affinitive peptides present innately in an endogenous silk fibroin, enabling optimized electrical stimulation to drive neurite outgrowth. Findings establish electrochemical‐biological link for biomaterial design rules for smart nerve guidance conduits that can provide low voltage ...
Rajiv Borah +5 more
wiley +1 more source
Cancer metabolism: The Warburg effect today
Experimental and Molecular Pathology, 2010 One of the first studies on the energy metabolism of a tumour was carried out, in 1922, in the laboratory of Otto Warburg. He established that cancer cells exhibited a specific metabolic pattern, characterized by a shift from respiration to fermentation, which has been later named the Warburg effect.
openaire +2 more sources
Defect‐Healed Au/rGO Coating for the Corrosion Protection of PEMFC Bipolar Plates
Advanced Materials Technologies, EarlyView.A defect‐healed gold/reduced graphene oxide (Au/rGO) coating is presented for stainless steel bipolar plates in polymer electrolyte membrane fuel cells. Gold nanoparticles nucleate at graphene oxide defects, blocking corrosive ion penetration and enhancing corrosion resistance, thereby ensuring durable fuel cell operation.
Jinmyeong Seo +6 more
wiley +1 more source
A moment in time: from the digital record of a migrating library [PDF]
, 2005 This paper draws on the work of the Arts & Humanities Research Council-funded Glasgow Cassirer Project, which makes correspondence and documents relating to the German philosopher Ernst Cassirer (1874-1945) available online. The paper concentrates on
Whitaker, G.
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