A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
Nature Communications, 2019 Pulmonary hypertension is characterized by a metabolic switch similar to the Warburg effect in cancer. Here Dabral et al. describe a RASSF1a-HIF-1α feedforward loop driving the Warburg effect both in a mouse model of hypoxia-induced pulmonary ...
Swati Dabral +14 more
doaj +1 more source
Host-Directed Therapy in Tuberculosis: Targeting Host Metabolism
Frontiers in Immunology, 2020 Mycobacterium tuberculosis (Mtb) has complex and intricate interactions with host immune cells. Mtb can survive, persist, and grow within macrophages and thereby circumvent detection by the innate immune system.
Jae-Sung Kim +5 more
doaj +1 more source
A moment in time: from the digital record of a migrating library [PDF]
, 2005 This paper draws on the work of the Arts & Humanities Research Council-funded Glasgow Cassirer Project, which makes correspondence and documents relating to the German philosopher Ernst Cassirer (1874-1945) available online. The paper concentrates on
Whitaker, G.
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Advanced Healthcare Materials, EarlyView.Neural electrodes face a mechanical mismatch with brain tissue. This study proposes a bioelectromechanical coupling strategy using an ultra‐flexible electrode designed for synchronized motion. Optimized to match brain tissue stiffness, it achieves dual signal acquisition and micromotion sensing, with characterized interfacial forces and piezoresistive ...
Donglei Chen +11 more
wiley +1 more source
The metabolomic profile of gamma-irradiated human hepatoma and muscle cells reveals metabolic changes consistent with the Warburg effect [PDF]
, 2016 The two human cell lines HepG2 from hepatoma and HMCL-7304 from striated muscle were γ-irradiated with doses between 0 and 4 Gy. Abundant γH2AX foci were observed at 4 Gy after 4 h of culture post-irradiation.
Beyoğlu, Diren +4 more
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Advanced Materials, EarlyView.It is demonstrated that contact resistance is effectively eliminated in two‐probe micropore device metal/protein/metal bioelectronic junctions. These results, using two different protein types in these junctions, show that, as ultrathin (<40 nm) films, proteins are an even more efficient electronic transport medium than previously thought, when the ...
Sudipta Bera +6 more
wiley +1 more source
Study of the oxygen electrode reaction using mixed conducting oxide surface layers. Part II: Small signal analysis [PDF]
, 1986 The oxygen gas electrode has been studied for a number of mixed conducting oxide surface layers on top of Gd2Zr2O7 (TGZO) solid electrolytes. In part II of this paper we present the results of frequency dispersion measurements for the electrode reaction,
Burggraaf, A.J. +2 more
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Transient Charging of Mixed Ionic‐Electronic Conductors by Anomalous Diffusion
Advanced Materials, EarlyView.This article explores charge transport in mixed ionic‐electronic conductors (MIECs) through electrochemical impedance spectroscopy and transient current analysis. Focusing on PEDOT:PSS, WO3, and n‐doped PBDF, it uncovers the impact of anomalous diffusion via fractional modeling. The study reveals key correlations that deepen understanding and guide the
Heyi Zhang +9 more
wiley +1 more source
Battle of Vellinghausen: Lessons Learnt? A Study of the British army in the closing stages of the Seven Years War in Western Europe as studied through the Battle of Vellinghausen [PDF]
, 2019 This is a study of the British military actions in Western Germany during the Seven Years War, investigating the army’s ability in combat and analysing its improvements through the case study of the Battle of Vellinghausen.
Dodson, Samuel
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Metabolic Regulation of Epithelial to Mesenchymal Transition: Implications for Endocrine Cancer [PDF]
, 2019 York University ...
Bhattacharya, Debasmita, Scimè, Anthony
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