100 years of the Warburg effect: a historical perspective.
Otto Warburg published the first papers describing what became known as the Warburg effect in 1923. All that was known about glucose metabolism at that time was that it occurred in two stages: (i) fermentation or glycolysis, in which glucose was ...
D. Hardie
semanticscholar +1 more source
Metformin as a Therapeutic Target in Endometrial Cancers. [PDF]
Endometrial cancer is the most common gynecologic malignancy in developed countries. Its increasing incidence is thought to be related in part to the rise of metabolic syndrome, which has been shown to be a risk factor for the development of ...
Johnson, Jennifer +6 more
core +2 more sources
Optimizing (1‐x) BiFeO3‐xCaTiO3 Perovskites: A Pathway to Efficient Flexible Energy Storage
Perovskite materials, like BFO CTO, are popular due to their high conductivity, low cost, and wide availability. In this work a symmetric electrochemical cell based on BFO‐CTO shows a charge of 3.356 C.cm⁻2, giving a specific capacitance of 2.79 mF.cm⁻2 at 1 mV.s⁻2.
Febin Paul +7 more
wiley +1 more source
Warburg effect(s)—a biographical sketch of Otto Warburg and his impacts on tumor metabolism [PDF]
Virtually everyone working in cancer research is familiar with the "Warburg effect", i.e., anaerobic glycolysis in the presence of oxygen in tumor cells. However, few people nowadays are aware of what lead Otto Warburg to the discovery of this observation and how his other scientific contributions are seminal to our present knowledge of metabolic and ...
openaire +3 more sources
A negative feedback loop underlies the Warburg effect. [PDF]
AbstractAerobic glycolysis, or the Warburg effect, is used by cancer cells for proliferation while producing lactate. Although lactate production has wide implications for cancer progression, it is not known how this effect increases cell proliferation and relates to oxidative phosphorylation.
Jaiswal A, Singh R.
europepmc +4 more sources
Graft Copolymer‐Stabilized Liquid Metal Nanoparticles for Lithium‐Ion Battery Self‐Healing Anodes
This study presents a self‐healing liquid metal anode for lithium‐ion batteries, where graft copolymer‐stabilized eutectic gallium indium (EGaIn) nanoparticles enhance stability and rate performance. The fluorinated grafted copolymer forms ionic channels, preventing EGaIn aggregation and facilitating lithium‐ion migration.
Youngwoo Seo +12 more
wiley +1 more source
GLUT1 expression patterns in different Hodgkin lymphoma subtypes and progressively transformed germinal centers [PDF]
Background: Increased glycolytic activity is a hallmark of cancer, allowing staging and restaging with 18F-fluorodeoxyglucose-positron-emission-tomography (PET).
Agostinelli, Claudio +9 more
core +1 more source
Warburg Effect - a Consequence or the Cause of Carcinogenesis? [PDF]
Ever since its discovery (1924) the Warburg effect (aerobic glycolysis) remains an unresolved puzzle: why the aggressive cancer cells "prefer" to use the energetically highly inefficient method of burning the glucose at the cellular level? While in the course of the last 90 years several hypotheses have been suggested, to this date there is no clear ...
openaire +2 more sources
Reversing the Warburg Effect as a Treatment for Glioblastoma [PDF]
Glioblastoma multiforme (GBM), like most cancers, possesses a unique bioenergetic state of aerobic glycolysis known as the Warburg effect. Here, we documented that methylene blue (MB) reverses the Warburg effect evidenced by the increasing of oxygen consumption and reduction of lactate production in GBM cell lines.
Yi Wen +15 more
openaire +2 more sources
Cu2O/Cu Chiral Catalysts for Highly Selective Solar‐Assisted CO2‐to‐CO Electroreduction
To address the poor target‐product selectivity of the eCO2RR, breakthrough approaches based on the chiral‐induced spin selectivity phenomenon enhance the Faradaic efficiency (FE) for target hydrocarbons, such as CO. To induce this spin polarization strategy in Cu2O/Cu catalysts, it is proposed using amine‐based intermediate organic molecules with ...
Hyungsoo Lee +13 more
wiley +1 more source

