Results 241 to 250 of about 13,460,861 (391)

Bimetallic Nanozyme Amplifier for Synergistic Ferroptosis‐Cuproptosis and Metabolic Reprogramming to Reshape Immunosuppressive Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
The Bimetallic Nanozyme Amplifier (PEG@AuCZ@CC) to maximize hydrogen peroxide production and reprogram tumor metabolism from glycolysis to oxidative phosphorylation. This shift enhances ferroptotic/cuproptotic signaling cascades and creates a glucose‐enriched but lactate‐depleted tumor microenvironment (TME), effectively overcoming immune tolerance in ...
Jianzhang Luo   +9 more
wiley   +1 more source

mTORC2 dictates Warburg effect and drug resistance [PDF]

open access: bronze, 2014
Kenta Masui   +2 more
openalex   +1 more source

A Dual‐Target Recognition System Based on Acid‐Degradable Ni‐MOF and Aptamer Guidance for Precise Tumor Diagnosis and Combined Therapy

open access: yesAdvanced Science, EarlyView.
This work reports a Ni‐doped ZIF‐8 nanoplatform co‐encapsulating glucose oxidase and horseradish peroxidase, enabling a cascade catalytic reaction that produces hydroxyl radicals from endogenous glucose and hydrogen peroxide. Upon near‐infrared irradiation, the system simultaneously achieves photothermal and chemodynamic therapy, offering an effective ...
Jing Xu   +8 more
wiley   +1 more source

miR-6126 modulates GRP78 to suppress the Warburg effect and mitochondrial dynamics in triple-negative breast cancer. [PDF]

open access: yesInt J Med Sci
Wang WJ   +8 more
europepmc   +1 more source

Synergistic Ni‐Co Metal Nodes in a Conjugated MOF‐Modified Separator for High‐Performance Lithium‐Sulfur Batteries

open access: yesAdvanced Science, EarlyView.
In this work, the employment of cMOFs is reported as modified materials for LSB separators. It is proved that cMOF with in‐plane d‐π conjugation is a good barrier layer for constructing high‐performance LSBs. Through a series of in situ and non in situ electrochemical examinations, LSB assembled with Ni1.35Co1.65(HHTP)2 separator exhibits excellent ...
Yuanhang Xu   +6 more
wiley   +1 more source

Structure, function and inhibition of poly(ADP-ribose)polymerase, member 14 (PARP14) [PDF]

open access: yes, 2018
Levonis, Stephan M   +3 more
core   +1 more source

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