Results 1 to 10 of about 57,794 (383)

Identification of key genes in sepsis by WGCNA

open access: hybridPreventive Medicine, 2023
When the body damages its own tissues in response to an infection, sepsis develops. Medical treatments are limited. It's important to understand the molecular mechanism behind sepsis pathogenesis and identify potential molecular treatment targets.
Xuemeng Gao   +4 more
semanticscholar   +4 more sources

Transcriptome and WGCNA reveal hub genes in sugarcane tiller seedlings in response to drought stress [PDF]

open access: goldScientific Reports, 2023
Drought stress can severely affect sugarcane growth and yield. The objective of this research was to identify candidate genes in sugarcane tillering seedlings in response to drought stress.
Yuwei Tang   +7 more
openalex   +2 more sources

Identification of Key Biomarkers Associated with Immunogenic Cell Death and Their Regulatory Mechanisms in Severe Acute Pancreatitis Based on WGCNA and Machine Learning

open access: yesInternational Journal of Molecular Sciences, 2023
Immunogenic cell death (ICD) is a form of programmed cell death with a strong sense of inflammatory detection, whose powerful situational awareness can cause the reactivation of aberrant immunity.
Hailong Chen
exaly   +2 more sources

Predicting the molecular mechanism of ginger targeting PRMT1/BTG2 axis to inhibit gastric cancer based on WGCNA and machine algorithms

open access: hybridPhytomedicine
OBJECTIVE The aim of this study was to screen the biomarkers of ginger against gastric cancer (GC) by network pharmacology, WGCNA and machine algorithms.
Guoqing Chen   +7 more
openalex   +2 more sources

Comprehensive Molecular Analyses of a Macrophage-Related Gene Signature With Regard to Prognosis, Immune Features, and Biomarkers for Immunotherapy in Hepatocellular Carcinoma Based on WGCNA and the LASSO Algorithm

open access: goldFrontiers in Immunology, 2022
Macrophages have been reported to exert a crucial role in hepatocellular carcinoma (HCC). This study aimed to explore the macrophage-related genes and establish a macrophage-related signature (MRS) model to predict the overall survival (OS) of patients ...
Tao Wang   +7 more
openalex   +2 more sources

Transcriptome Analysis of CD4+ T Cells in Coeliac Disease Reveals Imprint of BACH2 and IFNγ Regulation [PDF]

open access: yes, 2015
peer-reviewedData Availability: The raw sequencing reads (FASTQ files) and sequence read counts mapped to UCSC hg19 for each of the 74 transcriptomes sequenced in this study have been deposited at Gene Expression Omnibus (GEO) accession GSE69549.This ...
Castro, Patricia Dominguez   +7 more
core   +19 more sources

Prognostic analysis and validation of diagnostic marker genes in patients with osteoporosis

open access: yesFrontiers in Immunology, 2022
BackgroundsAs a systemic skeletal dysfunction, osteoporosis (OP) is characterized by low bone mass and bone microarchitectural damage. The global incidences of OP are high.MethodsData were retrieved from databases like Gene Expression Omnibus (GEO ...
Xing Wang   +9 more
doaj   +1 more source

Transcriptome profile analysis reveals the emamectin benzoate-induced genes associated with olfaction and metabolic detoxification in Spodoptera exigua Hübner (Lepidoptera: noctuidae)

open access: yesAll Life, 2022
Emamectin benzoate (EMB) is one of the high-efficacious pesticide commonly used to control the ferocious economic crop pest S. exigua in the field. The results of S.
Yang Sun   +9 more
doaj   +1 more source

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