Gene Co-expression Network and Copy Number Variation Analyses Identify Transcription Factors Associated With Multiple Myeloma Progression [PDF]
, 2019 Multiple myeloma (MM) has two clinical precursor stages of disease: monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM). However, the mechanism of progression is not well understood.
Abu Zaid, Mohammad +7 more
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Identifying Potential Diagnostic Genes for Diabetic Nephropathy Based on Hypoxia and Immune Status
Journal of Inflammation Research, 2021 Changyan Li,1 Feng Su,1 Le Zhang,2 Fang Liu,3 Wenxing Fan,1 Zhen Li,4 JingYuan Ma1 1Department of Nephrology, the First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, People’s Republic of China; 2Institute for Integrative ...
Li C +6 more
doaj
Identification of key genes and evaluation of immune cell infiltration in vitiligo
Mathematical Biosciences and Engineering, 2021 Background: To improve the understanding of the molecular mechanism of vitiligo is necessary to predict and formulate new targeted gene therapy strategies.
Xiangyue Zhang +4 more
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Global isoform-specific transcript alterations and deregulated networks in clear cell renal cell carcinoma. [PDF]
, 2018 Extensive genome-wide analyses of deregulated gene expression have now been performed for many types of cancer. However, most studies have focused on deregulation at the gene-level, which may overlook the alterations of specific transcripts for a given ...
Girke, Thomas +2 more
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Pharmacogenomics and Personalized Medicine, 2021 Xiaoxue Xu,1 Yuehan Hao,1 Jiao Wu,2 Jing Zhao,1 Shuang Xiong3 1Department of Neurology, The First Hospital of China Medical University, Shenyang, People’s Republic of China; 2Department of Neurology, The People’s Hospital of Liaoning Province,
Xu X, Hao Y, Wu J, Zhao J, Xiong S
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Generalized gene co-expression analysis via subspace clustering using low-rank representation [PDF]
, 2019 BACKGROUND: Gene Co-expression Network Analysis (GCNA) helps identify gene modules with potential biological functions and has become a popular method in bioinformatics and biomedical research.
Huang, Kun, Wang, Tongxin, Zhang, Jie
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An ectomycorrhizal fungus alters sensitivity to jasmonate, salicylate, gibberellin, and ethylene in host roots. [PDF]
, 2020 The phytohormones jasmonate, gibberellin, salicylate, and ethylene regulate an interconnected reprogramming network integrating root development with plant responses against microbes.
Amirebrahimi, Mojgan +14 more
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Journal of Hepatocellular Carcinoma, 2023 Ziyi Cao,1,* Li Guan,1,* Runzhi Yu,1 Fan Yang,2 Jie Chen1 1Department of Gastroenterology, Huadong Hospital Affiliated to Fudan University, Shanghai, 200040, People’s Republic of China; 2Shanghai Key Laboratory of Clinical Geriatric Medicine ...
Cao Z, Guan L, Yu R, Yang F, Chen J
doaj
Transcriptomic signatures of neuronal differentiation and their association with risk genes for autism spectrum and related neuropsychiatric disorders. [PDF]
, 2016 Genes for autism spectrum disorders (ASDs) are also implicated in fragile X syndrome (FXS), intellectual disabilities (ID) or schizophrenia (SCZ), and converge on neuronal function and differentiation. The SH-SY5Y neuroblastoma cell line, the most widely
Chiocchetti, AG +10 more
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Peripheral blood gene expression reveals an inflammatory transcriptomic signature in Friedreich's ataxia patients. [PDF]
, 2018 Transcriptional changes in Friedreich's ataxia (FRDA), a rare and debilitating recessive Mendelian neurodegenerative disorder, have been studied in affected but inaccessible tissues-such as dorsal root ganglia, sensory neurons and cerebellum-in animal ...
Coppola, Giovanni +11 more
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