Results 21 to 30 of about 45,444 (316)

Identification and Analysis of Potential Autophagy-Related Biomarkers in Endometriosis by WGCNA [PDF]

Frontiers in Molecular Biosciences, 2021
Background: Endometriosis is a serious gynecological disorder characterized by debilitating pain, infertility and the establishment of innervated endometriosis lesions outside the uterus. Early detection and accurate diagnosis are pivotal in endometriosis.
Jing Wang, Shanshan Cong, Han Wu, Yanan He, Xiaoli Liu, Liyuan Sun, Xibo Zhao, Guangmei Zhang   +7 more
openaire   +3 more sources

Identification of early diagnostic biomarkers via WGCNA in gastric cancer

Biomedicine & Pharmacotherapy, 2022
Gastric cancer (GC) is the world's second-leading cause of cancer-related mortality, continuing to make it a serious healthcare concern. Even though the prevalence of GC reduces, the prognosis for GC patients remains poor in terms of a lack of reliable biomarkers to diagnose early GC and predict chemosensitivity and recurrence.We integrated the gene ...
Rezaei Z., Ranjbaran J., Safarpour H., Nomiri S., Salmani F., Chamani E., Larki P., Brunetti O., Silvestris N., Tavakoli T.   +9 more
openaire   +3 more sources

WGCNA and molecular docking identify hub genes for cardiac aging

Frontiers in Cardiovascular Medicine, 2023
BackgroundCardiac aging and ageing-related cardiovascular diseases remain increase medical and social burden. Discovering the molecular mechanisms associated with cardiac aging is expected to provide new perspectives for delaying aging and related disease treatment.MethodsThe samples in GEO database were divided into older group and younger group based
Ping Ping, Lixun Guan, Chaoxue Ning, Qiong Liu, Yali Zhao, Xiang Zhu, Ting Yang, Shihui Fu, Shihui Fu   +8 more
openaire   +3 more sources

Intracellular metabolites in marine microorganisms during an experiment evaluating microbial mortality [PDF]

, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Longnecker, K., & Kujawinski, E. B.
Kujawinski, Elizabeth B., Longnecker, Krista   +1 more
core   +1 more source

Identification of Survival-Associated Hub Genes in Pancreatic Adenocarcinoma Based on WGCNA [PDF]

Frontiers in Genetics, 2022
Pancreatic adenocarcinoma is one of the leading causes of cancer-related death worldwide. Since little clinical symptoms were shown in the early period of pancreatic adenocarcinoma, most patients were found to carry metastases when diagnosis. The lack of effective diagnosis biomarkers and therapeutic targets makes pancreatic adenocarcinoma difficult to
Liya Huang, Ting Ye, Jingjing Wang, Xiaojing Gu, Ruiting Ma, Lulu Sheng, Binwu Ma   +6 more
openaire   +3 more sources

RETRACTED: Identification of Early Diagnostic and Prognostic Biomarkers via WGCNA in Stomach Adenocarcinoma [PDF]

Frontiers in Oncology, 2021
Stomach adenocarcinoma (STAD) is a leading cause of cancer deaths, and the outcome of the patients remains dismal for the lack of effective biomarkers of early detection. Recent studies have elucidated the landscape of genomic alterations of gastric cancer and reveal some biomarkers of advanced-stage gastric cancer, however, information about early ...
Ruoyue Tan, Ruoyue Tan, Ruoyue Tan, Guanghui Zhang, Guanghui Zhang, Ruochen Liu, Ruochen Liu, Jianbing Hou, Jianbing Hou, Zhen Dong, Zhen Dong, Chaowei Deng, Chaowei Deng, Sicheng Wan, Sicheng Wan, Xiaodong Lai, Hongjuan Cui, Hongjuan Cui, Hongjuan Cui   +18 more
openaire   +3 more sources

Maximal information component analysis: a novel non-linear network analysis method. [PDF]

, 2013
BackgroundNetwork construction and analysis algorithms provide scientists with the ability to sift through high-throughput biological outputs, such as transcription microarrays, for small groups of genes (modules) that are relevant for further research ...
Bennett, Brian, Lusis, Aldons J, Orozco, Luz D, Rau, Christoph D, Weiss, James, Wisniewski, Nicholas   +5 more
core   +3 more sources

Positively Correlated miRNA-miRNA Regulatory Networks in Mouse Frontal Cortex During Early Stages of Alcohol Dependence [PDF]

, 2013
Although the study of gene regulation via the action of specific microRNAs (miRNAs) has experienced a boom in recent years, the analysis of genome-wide interaction networks among miRNAs and respective targeted mRNAs has lagged behind.
Blednov, Yuri A., Gorini, Giorgio, Harris, R. Adon, Mayfield, R. Dayne, Nunez, Yury O., Ponomareva, Olga N., Truitt, Jay M.   +6 more
core   +2 more sources

Identification of therapeutic targets and prognostic biomarkers in cholangiocarcinoma via WGCNA

Frontiers in Oncology, 2022
BackgroundCholangiocarcinoma (CCA) is a highly aggressive malignant tumor for which limited treatment methods and prognostic signatures are available. This study aims to identify potential therapeutic targets and prognostic biomarkers for CCA.MethodsBased on differentially expressed genes (DEGs) identified from The Cancer Genome Atlas (TCGA) data, our ...
Lei Xu, Ting Xiao, Ling Xu, Wei Yao
openaire   +3 more sources

Comparative transcriptomic and weighted gene co-expression network analysis to identify the core genes in the cultivars of Musa acuminata under both infected and chemical perturbated conditions

Plant Signaling & Behavior, 2023
Banana is a high nutrient crop, which ranks fourth in terms of gross value production. Fusarium wilt of banana, caused by Fusarium oxysporum f. sp. cubense tropical race 4 (FocTR4), is considered the most destructive disease leading to the complete loss ...
PTV Lakshmi, Amrendra Kumar, Ajna A. S., Abitha P Raveendran, Anjali Chaudhary, Adhitthan Shanmugam, Annamalai Arunachalam   +6 more
doaj   +1 more source