Results 31 to 40 of about 37,320 (316)

Identification of an Immune-Related Gene Diagnostic Model and Potential Drugs in Sepsis Using Bioinformatics and Pharmacogenomics Approaches

Infection and Drug Resistance, 2023
Peng Chen,1 Juan Chen,2 Jinghe Ye,1 Limin Yang1 1Department of Urology, General Hospital of Northern Theater Command PLA, Shenyang, People’s Republic of China; 2Department of Oncology, General Hospital of Northern Theater Command PLA, Shenyang, People’s ...
Chen P, Chen J, Ye J, Yang L
doaj  

WGCNA combined with machine learning algorithms for analyzing key genes and immune cell infiltration in heart failure due to ischemic cardiomyopathy

Frontiers in Cardiovascular Medicine, 2023
Background Ischemic cardiomyopathy (ICM) induced heart failure (HF) is one of the most common causes of death worldwide. This study aimed to find candidate genes for ICM-HF and to identify relevant biomarkers by machine learning (ML).
Xiangjin Kong, Hourong Sun, Kaiming Wei, Lingwei Meng, Xing Lv, Chuanzhen Liu, Fushun Lin, Xinghua Gu   +7 more
semanticscholar   +1 more source

No association between war-related trauma or PTSD symptom severity and epigenome-wide DNA methylation in Burundian refugees

European Journal of Psychotraumatology, 2023
Background: War-related trauma is associated with varying posttraumatic stress disorder (PTSD) prevalence rates in refugees. In PTSD development, differential DNA methylation (DNAm) levels associated with trauma exposure might be involved in risk versus ...
Katharina Mattonet, Florian Scharpf, Katrin Block, Robert Kumsta, Tobias Hecker   +4 more
doaj   +1 more source

Transcriptome and WGCNA reveal hub genes in sugarcane tiller seedlings in response to drought stress

Scientific Reports, 2023
Drought stress can severely affect sugarcane growth and yield. The objective of this research was to identify candidate genes in sugarcane tillering seedlings in response to drought stress.
Yuwei Tang, Jiahui Li, Qiqi Song, Qin Cheng, Qinliang Tan, Quanguang Zhou, Zemei Nong, Ping Lv   +7 more
semanticscholar   +1 more source

Integrative Analysis From Multicenter Studies Identifies a WGCNA-Derived Cancer-Associated Fibroblast Signature for Ovarian Cancer

Frontiers in Immunology, 2022
Cancer-associated fibroblasts (CAFs) are a major contributor to tumor stromal crosstalk in the tumor microenvironment (TME) and boost tumor progression by promoting angiogenesis and lymphangiogenesis.
Songwei Feng, Yi Xu, Zhu Dai, Han Yin, Kecheng Zhang, Yang Shen   +5 more
semanticscholar   +1 more source

Identification of Key Modules and Hub Genes Involved in Regulating the Color of Chicken Breast Meat Using WGCNA

Animals, 2023
Simple Summary To explore the gene networks and key genes involved in the regulation in meat color of chicken breast muscle, weighted gene co-expression network analysis (WGCNA) was performed based on transcriptome data from the pectoralis major muscle ...
Xing Guo, H. Zhang, Hao Wang, Xinxin He, Jiangxian Wang, Wei Wei, Meng Liu, Jinmei Xu, Yanan Liu, R. Jiang   +9 more
semanticscholar   +1 more source

Identification of Potential Early Diagnostic Biomarkers of Sepsis

Journal of Inflammation Research, 2021
Zhenhua Li,1,2,* Bin Huang,2,* Wenfeng Yi,2,* Fei Wang,1 Shizhuang Wei,1 Huaixing Yan,1 Pan Qin,1 Donghua Zou,1 Rongguo Wei,3 Nian Chen4 1Department of Emergency Medicine, The Fifth Affiliated Hospital of Guangxi Medical University, Nanning, 530022 ...
Li Z, Huang B, Yi W, Wang F, Wei S, Yan H, Qin P, Zou D, Wei R, Chen N   +9 more
doaj  

M1 macrophage-related prognostic model by combining bulk and single-cell transcriptomic data in NSCLC [PDF]

Exploration of Medicine
Aim: Lung cancer is the leading cause of cancer-related deaths worldwide. Non-small cell lung cancer (NSCLC) is the most common subtype. Despite recent advancements in diagnostics and therapies, only a small percentage of patients benefit from ...
Zhe Liu, Fang Liu, Olutomilayo Olayemi Petinrin, Muhammad Toseef, Nanjun Chen, Zhongxu Zhu, Ka-Chun Wong   +6 more
doaj   +1 more source

CWGCNA: an R package to perform causal inference from the WGCNA framework

NAR Genomics and Bioinformatics
WGCNA (weighted gene co-expression network analysis) is a very useful tool for identifying co-expressed gene modules and detecting their correlations to phenotypic traits.
Yu Liu
semanticscholar   +1 more source

Identification of unique transcriptomic signatures through integrated multispecies comparative analysis and WGCNA in bovine oocyte development

BMC Genomics, 2023
Background Cattle ( Bos taurus ) are a major large livestock, however, compared with other species, the transcriptional specificity of bovine oocyte development has not been emphasised.
Fali Zhang, Weidong Li, Geng Zhang, M. Zhang, Zhaolin Liu, Ke-xin Zhu, Qing-Chun Liu, Shu-Er Zhang, Wei Shen, Xi-Feng Zhang   +9 more
semanticscholar   +1 more source