Results 41 to 50 of about 45,444 (316)

Comparative Transcriptome and WGCNA RevealKey Genes Involved in Lignocellulose Degradation in Sarcomyxa Edulis [PDF]

open access: yesScientific Reports, 2022
Abstract In order to explore the molecular mechanism of Sarcomyxa edulis response to lignocelluloses degradation, the developmental transcriptomes was analyzed for six stages covering the whole developmental process, including mycelium growing to half bag (B1), mycelium in cold stimulation after full bag (B2), mycelium in primordia appearing ...
Chao Duan   +5 more
openaire   +3 more sources

Co-expression networks in generation of induced pluripotent stem cells. [PDF]

open access: yes, 2016
We developed an adenoviral vector, in which Yamanaka's four reprogramming factors (RFs) were controlled by individual CMV promoters in a single cassette (Ad-SOcMK). This permitted coordinated expression of RFs (SOX2, OCT3/4, c-MYC and KLF4) in a cell for
Coppola, Giovanni   +6 more
core   +2 more sources

Identification of key pathways and genes in nasopharyngeal carcinoma based on WGCNA

open access: yesAuris Nasus Larynx, 2023
We aim to identify the potential genes and signaling pathways associated with the nasopharyngeal carcinoma (NPC) prognosis using Weighted Gene Co-Expression Network Analysis (WGCNA).Gene Expression Omnibus (GEO) query was utilized to download two NPC mRNA microarray data.
Yongmei, Dai   +7 more
openaire   +2 more sources

Identification of Potential Early Diagnostic Biomarkers of Sepsis

open access: yesJournal of Inflammation Research, 2021
Zhenhua Li,1,2,* Bin Huang,2,* Wenfeng Yi,2,* Fei Wang,1 Shizhuang Wei,1 Huaixing Yan,1 Pan Qin,1 Donghua Zou,1 Rongguo Wei,3 Nian Chen4 1Department of Emergency Medicine, The Fifth Affiliated Hospital of Guangxi Medical University, Nanning, 530022 ...
Li Z   +9 more
doaj  

M1 macrophage-related prognostic model by combining bulk and single-cell transcriptomic data in NSCLC [PDF]

open access: yesExploration of Medicine
Aim: Lung cancer is the leading cause of cancer-related deaths worldwide. Non-small cell lung cancer (NSCLC) is the most common subtype. Despite recent advancements in diagnostics and therapies, only a small percentage of patients benefit from ...
Zhe Liu   +6 more
doaj   +1 more source

Identification of Gene Co-Expression Modules and Core Genes Related to Immune Disorders in Major Depression Disorder

open access: yesInternational Journal of General Medicine, 2021
Lei Zhang,1,* Haibo Zhang,2,* Jiadong Xie,3,* Xu Wang4 1School of Public Administration, Hohai University, Nanjing, People’s Republic of China; 2Organization of Personnel Division, Jiangsu Provincial People’s Hospital (The First Affiliated ...
Zhang L, Zhang H, Xie J, Wang X
doaj  

Identification of Underlying Hub Genes Associated with Hypertrophic Cardiomyopathy by Integrated Bioinformatics Analysis

open access: yesPharmacogenomics and Personalized Medicine, 2021
Zetao Ma,1,2,* Xizhi Wang,1,* Qingbo Lv,1 Yingchao Gong,1 Minghong Xia,1 Lenan Zhuang,1 Xue Lu,1 Ying Yang,1 Wenbin Zhang,1 Guosheng Fu,1 Yang Ye,1 Dongwu Lai1 1Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang ...
Ma Z   +11 more
doaj  

Light-responsive expression atlas reveals the effects of light quality and intensity in Kalanchoë fedtschenkoi, a plant with crassulacean acid metabolism. [PDF]

open access: yes, 2020
BackgroundCrassulacean acid metabolism (CAM), a specialized mode of photosynthesis, enables plant adaptation to water-limited environments and improves photosynthetic efficiency via an inorganic carbon-concentrating mechanism.
Borland, Anne M   +17 more
core   +2 more sources

Identification of candidate biomarkers for GBM based on WGCNA

open access: yesScientific Reports
AbstractGlioblastoma multiforme (GBM), the most aggressive form of primary brain tumor, poses a considerable challenge in neuro-oncology. Despite advancements in therapeutic approaches, the prognosis for GBM patients remains bleak, primarily attributed to its inherent resistance to conventional treatments and a high recurrence rate. The primary goal of
Qinghui Sun   +5 more
openaire   +3 more sources

Identification of Critical Modules and Biomarkers of Ulcerative Colitis by Using WGCNA

open access: yesJournal of Inflammation Research, 2023
Ulcerative colitis (UC) is a chronic inflammatory disease of the colon and rectum that has no exact cause and is characterized by relapsing and remitting episodes. We aimed to find biomarkers of UC and its causes.We got GSE73661 from the GEO database and used WGCNA to find DEGs that were expressed in the same way in both normal and UC samples.
Yuan,Yifan, Li,Na, Fu,Mingyue, Ye,Mei
openaire   +4 more sources

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