Results 41 to 50 of about 57,794 (383)

Functional investigation and two-sample Mendelian randomization study of neuropathic pain hub genes obtained by WGCNA analysis

Frontiers in Neuroscience, 2023
Objective Neuropathic pain as a complex chronic disease that occurs after neurological injury, however the underlying mechanisms are not clarified in detail, hence therapeutic options are limited.
Jianfeng Zeng, Ch Lai, Jianwei Luo, Li Li   +3 more
semanticscholar   +1 more source

Assessment of Weighted Gene Co-Expression Network Analysis to Explore Key Pathways and Novel Biomarkers in Muscular Dystrophy

Pharmacogenomics and Personalized Medicine, 2021
Xiaoxue Xu,1 Yuehan Hao,1 Jiao Wu,2 Jing Zhao,1 Shuang Xiong3 1Department of Neurology, The First Hospital of China Medical University, Shenyang, People’s Republic of China; 2Department of Neurology, The People’s Hospital of Liaoning Province,
Xu X, Hao Y, Wu J, Zhao J, Xiong S
doaj  

WGCNA and transcriptome profiling reveal hub genes for key development stage seed size/oil content between wild and cultivated soybean

BMC Genomics, 2023
Background Soybean is one of the most important oil crops in the world. The domestication of wild soybean has resulted in significant changes in the seed oil content and seed size of cultivated soybeans.
Yanjie Yao, Erhui Xiong, Xuelian Qu, Junfeng Li, Hongli Liu, L. Quan, Wenyan Lu, Xuling Zhu, Meilin Chen, Ke Li, Xiaoming Chen, Yun Lian, Weiguo Lu, Dan Zhang, Xinan Zhou, Shanshan Chu, Yongqing Jiao   +16 more
semanticscholar   +1 more source

High Expression of Heterogeneous Nuclear Ribonucleoprotein A1 Facilitates Hepatocellular Carcinoma Growth

Journal of Hepatocellular Carcinoma, 2023
Ziyi Cao,1,* Li Guan,1,* Runzhi Yu,1 Fan Yang,2 Jie Chen1 1Department of Gastroenterology, Huadong Hospital Affiliated to Fudan University, Shanghai, 200040, People’s Republic of China; 2Shanghai Key Laboratory of Clinical Geriatric Medicine ...
Cao Z, Guan L, Yu R, Yang F, Chen J
doaj  

Transcriptomic signatures of neuronal differentiation and their association with risk genes for autism spectrum and related neuropsychiatric disorders. [PDF]

, 2016
Genes for autism spectrum disorders (ASDs) are also implicated in fragile X syndrome (FXS), intellectual disabilities (ID) or schizophrenia (SCZ), and converge on neuronal function and differentiation. The SH-SY5Y neuroblastoma cell line, the most widely
Chiocchetti, AG, Cocchi, E, de la Torre-Ubieta, L, Freitag, CM, Fulda, S, Geschwind, DH, Haslinger, D, Lindlar, S, Rothämel, T, Stein, JL, Waltes, R   +10 more
core   +1 more source

Identification and verification of diagnostic biomarkers in recurrent pregnancy loss via machine learning algorithm and WGCNA

Frontiers in Immunology, 2023
Background Recurrent pregnancy loss defined as the occurrence of two or more pregnancy losses before 20-24 weeks of gestation, is a prevalent and significant pathological condition that impacts human reproductive health. However, the underlying mechanism
Changqiang Wei, Yiyun Wei, Jinlian Cheng, X. Tan, Zhuolin Zhou, Shanshan Lin, Lihong Pang   +6 more
semanticscholar   +1 more source

Identification of Immune-Related Key Genes in Ovarian Cancer Based on WGCNA [PDF]

Frontiers in Genetics, 2021
Background: Ovarian cancer (OV) is a fatal gynecologic malignancy and has poor survival rate in women over the age of forty. In our study, we aimed to identify genes related to immune microenvironment regulations and explore genes associated with OV prognosis.Methods: The RNA-seq data of GDC TCGA Ovarian Cancer cohort of 376 patients was retrieved from
Qingli Quan, Qingli Quan, Xinxin Xiong, Shanyun Wu, Meixing Yu   +4 more
openaire   +3 more sources

An ectomycorrhizal fungus alters sensitivity to jasmonate, salicylate, gibberellin, and ethylene in host roots. [PDF]

, 2020
The phytohormones jasmonate, gibberellin, salicylate, and ethylene regulate an interconnected reprogramming network integrating root development with plant responses against microbes.
Amirebrahimi, Mojgan, Barry, Kerrie W, Basso, Veronica, Block, Jonathan, Daguerre, Yohann, Grigoriev, Igor V, Guinet, Frédéric, Kohler, Annegret, Martin, Francis, Miyauchi, Shingo, Na, Hyunsoo, Novák, Ondřej, Singan, Vasanth, Veneault-Fourrey, Claire, Šimura, Jan   +14 more
core   +3 more sources

Weighted Gene Co-Expression Network Analysis (WGCNA) Discovered Novel Long Non-Coding RNAs for Polycystic Ovary Syndrome

Biomedicines, 2023
Polycystic ovary syndrome (PCOS) affects reproductive-age women. This condition causes infertility, insulin resistance, obesity, and heart difficulties. The molecular basis and mechanism of PCOS might potentially generate effective treatments.
Roozbeh Heidarzadehpilehrood, Maryam Pirhoushiaran, Malina Binti Osman, Habibah Abdul Hamid, K. Ling   +4 more
semanticscholar   +1 more source

Identification of crucial genes in abdominal aortic aneurysm by WGCNA

PeerJ, 2019
Background Abdominal aortic aneurysm (AAA) is the full thickness dilation of the abdominal aorta. However, few effective medical therapies are available. Thus, elucidating the molecular mechanism of AAA pathogenesis and exploring the potential molecular target of medical therapies for AAA is of vital importance.
Siliang Chen, Dan Yang, Chuxiang Lei, Yuan Li, Xiaoning Sun, Mengyin Chen, Xiao Wu, Yuehong Zheng   +7 more
openaire   +3 more sources