Results 41 to 50 of about 37,320 (316)

Identification of Gene Co-Expression Modules and Core Genes Related to Immune Disorders in Major Depression Disorder

International Journal of General Medicine, 2021
Lei Zhang,1,* Haibo Zhang,2,* Jiadong Xie,3,* Xu Wang4 1School of Public Administration, Hohai University, Nanjing, People’s Republic of China; 2Organization of Personnel Division, Jiangsu Provincial People’s Hospital (The First Affiliated ...
Zhang L, Zhang H, Xie J, Wang X
doaj  

Identification and validation of immune and cuproptosis - related genes for diabetic nephropathy by WGCNA and machine learning

Frontiers in Immunology
Background As the leading cause of chronic kidney disease, diabetic kidney disease (DKD) is an enormous burden for all healthcare systems around the world. However, its early diagnosis has no effective methods.
Yubing Chen, Lijuan Liao, Baoju Wang, Zhan Wu   +3 more
semanticscholar   +1 more source

GWAS Combined with WGCNA of Transcriptome and Metabolome to Excavate Key Candidate Genes for Rice Anaerobic Germination

Rice, 2023
Direct seeding of rice is a lightweight and simple cultivation method, which can effectively promote rice production. Anaerobic germination tolerance is one of the main traits of rice adaptability to direct seeding.
Dandan Li, Kai Liu, Chuanchao Zhao, Siyi Liang, Jing Yang, Ziai Peng, Aoyun Xia, Meng Yang, Lixin Luo, Cuihong Huang, Jiafeng Wang, Ming Huang, Wuming Xiao, Hui Wang, Ling Su, T. Guo   +15 more
semanticscholar   +1 more source

RNA-Seq-Based WGCNA and Association Analysis Reveal the Key Regulatory Module and Genes Responding to Salt Stress in Wheat Roots

Plants
Soil salinization is the main abiotic stressor faced by crops. An improved understanding of the transcriptional response to salt stress in roots, the organ directly exposed to a high salinity environment, can inform breeding strategies to enhance ...
Jiating Chen, Lei Zhang, Yingxi Liu, Xinyao Shen, Yujing Guo, Xiaofei Ma, Xiaojun Zhang, Xin Li, Tianling Cheng, Huiqin Wen, Linyi Qiao, Z. Chang   +11 more
semanticscholar   +1 more source

Genetic architecture and key regulatory genes of fatty acid composition in Gushi chicken breast muscle determined by GWAS and WGCNA

BMC Genomics, 2023
Background Fatty acids composition in poultry muscle is directly related to its tenderness, flavour, and juiciness, whereas its genetic mechanisms have not been elucidated.
Shengxin Fan, Pengtao Yuan, Shuaihao Li, Hongtai Li, Bin Zhai, Yuanfang Li, Hongyuan Zhang, Jinxin Gu, Hong Li, Yadong Tian, X. Kang, Yanhua Zhang, Guoxi Li   +12 more
semanticscholar   +1 more source

Identification of crucial genes through WGCNA in the progression of gastric cancer

Journal of Cancer
Background: To explore the hub gene closely related to the progression of gastric cancer (GC), so as to provide a theoretical basis for revealing the therapeutic mechanism of GC.
Rui Liu, Jie Liu, Qiang Cao, Yanpeng Chu, Hao Chi, Jun Zhang, Jiangping Fu, Tianchi Zhang, Linguang Fan, Chaozhong Liang, Xiufang Luo, Xiaoli Yang, Bo Li   +12 more
semanticscholar   +1 more source

Platelets-related signature based diagnostic model in rheumatoid arthritis using WGCNA and machine learning

Frontiers in Immunology, 2023
Background and aim Rheumatoid arthritis (RA) is an autoinflammatory disease that may lead to severe disability. The diagnosis of RA is limited due to the need for biomarkers with both reliability and efficiency.
Yuchen Liu, Haixu Jiang, Tian Kang, Xiaojun Shi, Xiaoping Liu, Chen Li, Xiujuan Hou, Meiling Li   +7 more
semanticscholar   +1 more source

Identification of Underlying Hub Genes Associated with Hypertrophic Cardiomyopathy by Integrated Bioinformatics Analysis

Pharmacogenomics and Personalized Medicine, 2021
Zetao Ma,1,2,* Xizhi Wang,1,* Qingbo Lv,1 Yingchao Gong,1 Minghong Xia,1 Lenan Zhuang,1 Xue Lu,1 Ying Yang,1 Wenbin Zhang,1 Guosheng Fu,1 Yang Ye,1 Dongwu Lai1 1Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang ...
Ma Z, Wang X, Lv Q, Gong Y, Xia M, Zhuang L, Lu X, Yang Y, Zhang W, Fu G, Ye Y, Lai D   +11 more
doaj  

Identification of Critical Modules and Biomarkers of Ulcerative Colitis by Using WGCNA

Journal of Inflammation Research, 2023
Background Ulcerative colitis (UC) is a chronic inflammatory disease of the colon and rectum that has no exact cause and is characterized by relapsing and remitting episodes. We aimed to find biomarkers of UC and its causes.
Yifan Yuan, Na Li, M. Fu, Mei Ye
semanticscholar   +1 more source

Integrated transcriptomic and WGCNA analyses reveal candidate genes regulating mainly flavonoid biosynthesis in Litsea coreana var. sinensis

BMC Plant Biology
Litsea coreana Levl. var. sinensis (Allen) Yang et P. H. Huang is a popular ethnic herb and beverage plant known for its high flavonoid content, which has been linked to a variety of pharmacological benefits and crucial health-promoting impacts in humans.
Na Xie, Q. Guo, Huie Li, Gang-yi Yuan, Qin Gui, Yang Xiao, Mengyun Liao, Lan Yang   +7 more
semanticscholar   +1 more source