Results 51 to 60 of about 57,794 (383)

Identification of an Immune-Related Gene Diagnostic Model and Potential Drugs in Sepsis Using Bioinformatics and Pharmacogenomics Approaches

Infection and Drug Resistance, 2023
Peng Chen,1 Juan Chen,2 Jinghe Ye,1 Limin Yang1 1Department of Urology, General Hospital of Northern Theater Command PLA, Shenyang, People’s Republic of China; 2Department of Oncology, General Hospital of Northern Theater Command PLA, Shenyang, People’s ...
Chen P, Chen J, Ye J, Yang L
doaj  

Identification of key immune cell-related genes involved in tumorigenesis and prognosis of cervical squamous cell carcinoma

Human Vaccines & Immunotherapeutics, 2023
The infiltration of immune cells can significantly affect the prognosis and immune therapy of patients with cervical squamous cell carcinoma (CSCC). This study aimed to explore key immune cell-related genes in the tumorigenesis and prognosis of CSCC. The
Chunxiao Yan, Yanyan Ma, Junyan Li, Xuejun Chen, Jiong Ma   +4 more
doaj   +1 more source

Peripheral blood gene expression reveals an inflammatory transcriptomic signature in Friedreich's ataxia patients. [PDF]

, 2018
Transcriptional changes in Friedreich's ataxia (FRDA), a rare and debilitating recessive Mendelian neurodegenerative disorder, have been studied in affected but inaccessible tissues-such as dorsal root ganglia, sensory neurons and cerebellum-in animal ...
Coppola, Giovanni, Dokuru, Deepika, Farmer, Jennifer, Gao, Fuying, Isaacs, Charles, Lynch, David R, Nachun, Daniel, Perlman, Susan, Sears, Renee, Strawser, Cassandra, Van Berlo, Victoria, Yang, Zhongan   +11 more
core   +1 more source

Hub Gene Mining and Co-Expression Network Construction of Low-Temperature Response in Maize of Seedling by WGCNA

Genes, 2023
Weighted gene co-expression network analysis (WGCNA) is a research method in systematic biology. It is widely used to identify gene modules related to target traits in multi-sample transcriptome data.
Tao Yu, Jianguo Zhang, Jingsheng Cao, Xuena Ma, Wenyue Li, Gengbin Yang   +5 more
semanticscholar   +1 more source

Diel transcriptional response of a California Current plankton microbiome to light, low iron, and enduring viral infection. [PDF]

, 2019
Phytoplankton and associated microbial communities provide organic carbon to oceanic food webs and drive ecosystem dynamics. However, capturing those dynamics is challenging. Here, an in situ, semi-Lagrangian, robotic sampler profiled pelagic microbes at
Allen, AE, Allen, EE, Allen, L Zeigler, Aylward, FO, Chavez, FP, Delong, EF, Fontanez, KM, Kolody, BC, McCrow, JP, Moniruzzaman, M, Moustafa, A, Scholin, CA, Worden, AZ   +12 more
core   +2 more sources

Generalized gene co-expression analysis via subspace clustering using low-rank representation [PDF]

, 2019
BACKGROUND: Gene Co-expression Network Analysis (GCNA) helps identify gene modules with potential biological functions and has become a popular method in bioinformatics and biomedical research.
Huang, Kun, Wang, Tongxin, Zhang, Jie
core   +1 more source

Identification of hub genes regulating isoflavone accumulation in soybean seeds via GWAS and WGCNA approaches

Frontiers in Plant Science, 2023
Introduction Isoflavones are the secondary metabolites synthesized by the phenylpropanoid biosynthesis pathway in soybean that benefits human and plant health.
M. Azam, Shengrui Zhang, Jing Li, M. Ahsan, K. G. Agyenim-Boateng, J. Qi, Yue Feng, Yitian Liu, Bin Li, L. Qiu, Junming Sun   +10 more
semanticscholar   +1 more source

Comparative Transcriptome and WGCNA RevealKey Genes Involved in Lignocellulose Degradation in Sarcomyxa Edulis [PDF]

Scientific Reports, 2022
Abstract In order to explore the molecular mechanism of Sarcomyxa edulis response to lignocelluloses degradation, the developmental transcriptomes was analyzed for six stages covering the whole developmental process, including mycelium growing to half bag (B1), mycelium in cold stimulation after full bag (B2), mycelium in primordia appearing ...
Chao Duan, Feng-hua Tian, Lan Yao, Jian-Hua Lv, Chuan-Wen Jia, Chang-Tian Li   +5 more
openaire   +3 more sources

Identification of Potential Early Diagnostic Biomarkers of Sepsis

Journal of Inflammation Research, 2021
Zhenhua Li,1,2,* Bin Huang,2,* Wenfeng Yi,2,* Fei Wang,1 Shizhuang Wei,1 Huaixing Yan,1 Pan Qin,1 Donghua Zou,1 Rongguo Wei,3 Nian Chen4 1Department of Emergency Medicine, The Fifth Affiliated Hospital of Guangxi Medical University, Nanning, 530022 ...
Li Z, Huang B, Yi W, Wang F, Wei S, Yan H, Qin P, Zou D, Wei R, Chen N   +9 more
doaj  

M1 macrophage-related prognostic model by combining bulk and single-cell transcriptomic data in NSCLC [PDF]

Exploration of Medicine
Aim: Lung cancer is the leading cause of cancer-related deaths worldwide. Non-small cell lung cancer (NSCLC) is the most common subtype. Despite recent advancements in diagnostics and therapies, only a small percentage of patients benefit from ...
Zhe Liu, Fang Liu, Olutomilayo Olayemi Petinrin, Muhammad Toseef, Nanjun Chen, Zhongxu Zhu, Ka-Chun Wong   +6 more
doaj   +1 more source