Results 61 to 70 of about 57,794 (383)

Identification of key pathways and genes in nasopharyngeal carcinoma based on WGCNA

Auris Nasus Larynx, 2023
We aim to identify the potential genes and signaling pathways associated with the nasopharyngeal carcinoma (NPC) prognosis using Weighted Gene Co-Expression Network Analysis (WGCNA).Gene Expression Omnibus (GEO) query was utilized to download two NPC mRNA microarray data.
Yongmei, Dai, Wenhan, Chen, Junpeng, Huang, Li, Xie, Jianfang, Lin, Qianshun, Chen, Guicheng, Jiang, Chen, Huang   +7 more
openaire   +2 more sources

Identification of Gene Co-Expression Modules and Core Genes Related to Immune Disorders in Major Depression Disorder

International Journal of General Medicine, 2021
Lei Zhang,1,* Haibo Zhang,2,* Jiadong Xie,3,* Xu Wang4 1School of Public Administration, Hohai University, Nanjing, People’s Republic of China; 2Organization of Personnel Division, Jiangsu Provincial People’s Hospital (The First Affiliated ...
Zhang L, Zhang H, Xie J, Wang X
doaj  

Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure [PDF]

, 2019
Heart failure is a leading cause of mortality, yet our understanding of the genetic interactions underlying this disease remains incomplete. Here, we harvest 1352 healthy and failing human hearts directly from transplant center operating rooms, and ...
Ashley, Euan A., Bernstein, Daniel, Brandimarto, Jeff, Cappola, Thomas, Chang, Alex C., Chin, Elizabeth T., Connolly, Andrew, Cordero, Pablo, Depaoli-Roach, Anna A., Dewey, Frederick, Erbilgin, Ayca, Glazer, Nicole, Gloudemans, Michael J., Hakonarson, Hakon, Hannenhalli, Sridhar, Huang, Yong, Li, Hongzhe, Li, Mingyao, Lusis, Aldons J., Malloy, Christine, Margulies, Kenneth B., Montgomery, Stephen B., Moravec, Christine S., Morley, Michael, Parikh, Victoria N., Pavlovic, Aleksandra, Ritter, Scott, Shang, Ching, Skreen, Jamie, Smith, Kevin S., Tang, W. H. Wilson, Waggott, Daryl, Wheeler, Matthew T., Zaleta, Kathia, Zhao, Mingming   +34 more
core   +2 more sources

Identification of Key Modules and Hub Genes Involved in Regulating the Color of Chicken Breast Meat Using WGCNA

Animals, 2023
Simple Summary To explore the gene networks and key genes involved in the regulation in meat color of chicken breast muscle, weighted gene co-expression network analysis (WGCNA) was performed based on transcriptome data from the pectoralis major muscle ...
Xing Guo, H. Zhang, Hao Wang, Xinxin He, Jiangxian Wang, Wei Wei, Meng Liu, Jinmei Xu, Yanan Liu, R. Jiang   +9 more
semanticscholar   +1 more source

Co-expression networks in generation of induced pluripotent stem cells. [PDF]

, 2016
We developed an adenoviral vector, in which Yamanaka's four reprogramming factors (RFs) were controlled by individual CMV promoters in a single cassette (Ad-SOcMK). This permitted coordinated expression of RFs (SOX2, OCT3/4, c-MYC and KLF4) in a cell for
Coppola, Giovanni, Dansithong, Warunee, Figueroa, Karla P, Gao, Fuying, Paul, Sharan, Pflieger, Lance, Pulst, Stefan M   +6 more
core   +2 more sources

Amino acid metabolism pathways as key regulators of nitrogen distribution in tobacco: insights from transcriptome and WGCNA analyses

BMC Plant Biology
Nitrogen (N) is crucial for plant growth and is distributed across various N morphologies within plant organs. However, the mechanisms controlling the distribution of these N morphologies are not fully understood.
Shichen Li, Waqar Ahmed, Tao Jiang, Dehai Yang, Linyuan Yang, Xiaodong Hu, Meiwei Zhao, Xiaoci Peng, Yingfen Yang, Wei Zhang, Mingmin Li, Zhengxiong Zhao   +11 more
semanticscholar   +1 more source

Transcriptome Sequencing and WGCNA Reveal Key Genes in Response to Leaf Blight in Poplar

International Journal of Molecular Sciences, 2023
Leaf blight is a fungal disease that mainly affects the growth and development of leaves in plants. To investigate the molecular mechanisms of leaf blight defense in poplar, we performed RNA-Seq and enzyme activity assays on the Populus simonii × Populus
Ruiqi Wang, Yuting Wang, W. Yao, Wengong Ge, T. Jiang, Boru Zhou   +5 more
semanticscholar   +1 more source

Identification and validation of immune and cuproptosis - related genes for diabetic nephropathy by WGCNA and machine learning

Frontiers in Immunology
Background As the leading cause of chronic kidney disease, diabetic kidney disease (DKD) is an enormous burden for all healthcare systems around the world. However, its early diagnosis has no effective methods.
Yubing Chen, Lijuan Liao, Baoju Wang, Zhan Wu   +3 more
semanticscholar   +1 more source

Transcriptome-Based WGCNA Analysis Reveals the Mechanism of Drought Resistance Differences in Sweetpotato (Ipomoea batatas (L.) Lam.)

International Journal of Molecular Sciences, 2023
Sweetpotato (Ipomoea batatas (L.) Lam.) is a globally significant storage root crop, but it is highly susceptible to yield reduction under severe drought conditions.
Jikai Zong, Peitao Chen, Qingqing Luo, Jilong Gao, Ruihua Qin, Chunli Wu, Qina Lv, Tengfei Zhao, Yufan Fu   +8 more
semanticscholar   +1 more source

Identification of Underlying Hub Genes Associated with Hypertrophic Cardiomyopathy by Integrated Bioinformatics Analysis

Pharmacogenomics and Personalized Medicine, 2021
Zetao Ma,1,2,* Xizhi Wang,1,* Qingbo Lv,1 Yingchao Gong,1 Minghong Xia,1 Lenan Zhuang,1 Xue Lu,1 Ying Yang,1 Wenbin Zhang,1 Guosheng Fu,1 Yang Ye,1 Dongwu Lai1 1Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang ...
Ma Z, Wang X, Lv Q, Gong Y, Xia M, Zhuang L, Lu X, Yang Y, Zhang W, Fu G, Ye Y, Lai D   +11 more
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