Results 71 to 80 of about 37,320 (316)

Key Candidate Genes – VSIG2 of Colon Cancer Identified by Weighted Gene Co-Expression Network Analysis

Cancer Management and Research, 2021
Zhongze Cui,* Yangyang Li,* Shuang He, Feifei Wen, Xiaoyang Xu, Lizhen Lu, Shuhua Wu Department of Pathology, Binzhou Medical University Hospital, Binzhou, Shandong Province, People’s Republic of China*These authors contributed equally to ...
Cui Z, Li Y, He S, Wen F, Xu X, Lu L, Wu S   +6 more
doaj  

WGCNA Identifies Translational and Proteasome-Ubiquitin Dysfunction in Rett Syndrome [PDF]

, 2021
Florencia Haase, Brian Gloss, Patrick Tam, Wendy Gold   +3 more
openalex   +1 more source

CARD9 Conveys Pancreatic Islet Sympathetic Nervous β2 Signals to Reshape Macrophage Creatine Metabolism in Type 1 Diabetes

Advanced Science, EarlyView.
This study identifies CARD9 as a key mediator linking sympathetic β2‐adrenergic receptor signaling to macrophage creatine metabolism, inflammatory polarization, and neuronal integrity. Loss of β2‐AR‐PKA‐CREB1‐CARD9 signaling in macrophages reduces creatine uptake, promotes pro‐inflammatory macrophage activation, and drives sympathetic axon ferroptosis.
Huimin Yuan, Senlin Li, Shuai Liu, Hong Zhou, Yue Xu, Wenhui Li, Mengxuan Wang, Mengheng Wang, Mengzhu Zheng, Wenxi Shi, Xin Li, Yiting Feng, Ming Xiang   +12 more
wiley   +1 more source

Identification of the role of pyroptosis -related genes in chronic rhinosinusitis based on WGCNA [PDF]

, 2023
Yarui Wan, Yanfei Wang, Sheng Xu, Hui Du, Zhiqi Liu   +4 more
openalex   +1 more source

Identification of prognostic biomarkers in neuroblastoma using WGCNA and multi-omics analysis

Discover Oncology
Neuroblastoma (NB) is one of the most frequent parenchymal tumors among children, with a high degree of heterogeneity and wide variation in clinical presentation.
Yuhan Ke, Wenliang Ge
semanticscholar   +1 more source

ELAC2 Functions as a Key Gene in the Early Development of Placental Formation Based on WGCNA

Cells, 2023
The placenta plays a crucial role in mammalian fetal growth. The most important cell type in the placenta is the trophoblast cell. Many genes have been reported to play important functions in the differentiation of early placental trophoblast cells ...
Junyong Liang, Jingjie Liang, Q. Tan, Zhengguang Wang   +3 more
semanticscholar   +1 more source

Single‐Cell Dissection of the Biological Function and Molecular Features Underlying the Micropeptide LSMEM1 in Kidney

Advanced Science, EarlyView.
LSMEM1, an evolutionarily conserved micropeptide with extreme hydrophobicity (aliphatic index═113) and dynamic amphiphilicity (GRAVY═0.017), features a strong α‐helical transmembrane anchor (residues 64‐86). Single‐cell analysis reveals its critical role in renal lipid homeostasis.
Peimin Liu, Hong Zhang, Shanzhi Yang, Jiaoqing Li, Danfeng Wu, Haosen Xu, Huan Jiang, Yi Jing, Guoxiang Jin, Ruobing Liu, Ning Fan, Xiaoyan Bai   +11 more
wiley   +1 more source

Identification and validation of diagnostic and prognostic biomarkers in prostate cancer based on WGCNA

Discover Oncology
Prostate cancer (PCa) represents a significant health challenge for men, and the advancement of the disease often results in a grave prognosis for patients.
Xi Xiao, Liangliang Qing, Zonglin Li, Fuxiang Ye, Yajia Dong, Jun Mi, Junqiang Tian   +6 more
semanticscholar   +1 more source

IPGCA: A Comprehensive Single Cell Atlas of 1 074 127 Porcine Intestinal Cells Revealing Cellular Dynamics, Genetic Regulation, and Cross‐Species Conservation

Advanced Science, EarlyView.
A high resolution integrated cell atlas of the pig intestine provides insights into the genetic mechanisms of complex traits (Created in BioRender. Yu, P. (2025) https://BioRender.com/o14c563) Abstract The porcine intestinal tract is vital for nutrient absorption, immune regulation, and various physiological processes.
Pengfei Yu, Qinqin Xie, Xiaodian Cai, Zhanming Zhong, Ran Wei, He Han, Shuang Liu, Zhenyang Zhang, Lingyao Xu, Zitao Chen, Zhe Zhang, Qishan Wang, Yuchun Pan, Zhen Wang, Zhe Zhang   +14 more
wiley   +1 more source

Identification of candidate biomarkers for GBM based on WGCNA

Scientific Reports
Glioblastoma multiforme (GBM), the most aggressive form of primary brain tumor, poses a considerable challenge in neuro-oncology. Despite advancements in therapeutic approaches, the prognosis for GBM patients remains bleak, primarily attributed to its ...
Qinghui Sun, Zheng Wang, Hao Xiu, Na He, Mingyu Liu, Li Yin   +5 more
semanticscholar   +1 more source