Results 31 to 40 of about 253,274 (360)

De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis

open access: yesNature Communications, 2018
Long non-coding RNAs are known to regulate mouse white adipose tissue development and brown adipose tissue program expression. Here, the authors construct a roadmap for human long non-coding RNAs expressed in fetal brown adipose tissue, adult omental and
Chunming Ding   +12 more
doaj   +1 more source

Expression profiles and gene set enrichment analysis of the transcriptomes from the cancer tissue, white adipose tissue and paracancer tissue with colorectal cancer [PDF]

open access: yesPeerJ
Background Colorectal cancer (CRC) is one of the most common cancers worldwide and is related to diet and obesity. Currently, crosstalk between lipid metabolism and CRC has been reported; however, the specific mechanism is not yet understood.
Xiufeng Zhang   +9 more
doaj   +2 more sources

CD47 differentially regulates white and brown fat function

open access: yesBiology Open, 2020
Mechanisms that enhance energy expenditure are attractive therapeutic targets for obesity. Previously we have demonstrated that mice lacking cd47 are leaner, exhibit increased energy expenditure, and are protected against diet-induced obesity.
Heather Norman-Burgdolf   +3 more
doaj   +1 more source

Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissues in mice [PDF]

open access: yes, 2016
The present study aimed to determine the effect of thyroid hormone dysfunction on brown adipose tissue activity and white adipose tissue browning in mice.
Hankir, Mohammed [u.v.m.]   +8 more
core   +1 more source

The adipose tissue: something more than a reservoir of energy

open access: yesGrasas y Aceites, 2009
Adipose tissue is a reservoir of energy and also an organ that contributes to the aesthetics and health of human body working as an endocrine tissue. White adipose tissue, which is formed by unilocular adipose cells, can modify organic homeostasis by ...
Alfonso Valenzuela B, Julio Sanhueza C
doaj   +1 more source

Unraveling White Adipose Tissue Heterogeneity and Obesity by Adipose Stem/Stromal Cell Biology and 3D Culture Models

open access: yesCells, 2023
The immune and endocrine dysfunctions of white adipose tissue are a hallmark of metabolic disorders such as obesity and type 2 diabetes. In humans, white adipose tissue comprises distinct depots broadly distributed under the skin (hypodermis) and as ...
Leandra S. Baptista   +4 more
doaj   +1 more source

Polyunsaturated fatty acids stimulate de novo lipogenesis and improve glucose homeostasis during refeeding with high fat diet [PDF]

open access: yes, 2017
The recovery of body weight after a period of caloric restriction is accompanied by an enhanced efficiency of fat deposition and hyperinsulinemia—which are exacerbated by isocaloric refeeding on a high fat diet rich in saturated and monounsaturated ...
Bianco, Francesca   +7 more
core   +1 more source

Epigenetic regulation of white adipose tissue plasticity and energy metabolism by nucleosome binding HMGN proteins

open access: yesNature Communications, 2022
White adipose tissue browning plays an important role in regulating whole-body energy homeostasis and metabolism. Here the authors show that the HMGN nucleosome binding proteins epigenetically promote white adipocyte differentiation and modulate the rate
Ravikanth Nanduri   +9 more
doaj   +1 more source

Characterization of Cre recombinase models for the study of adipose tissue [PDF]

open access: yes, 2014
The study of adipose tissue in vivo has been significantly advanced through the use of genetic mouse models. While the aP2-CreBI and aP2-CreSalk lines have been widely used to target adipose tissue, the specificity of these lines for adipocytes has ...
Berry, Ryan   +7 more
core   +1 more source

Development of brown and white adipose tissue

open access: yesJournal of Lipid Research, 1975
In this review, it is assumed that the reader is familiar with the basic properties of white and brown adipose tissue. The role and metabolic characteristics of both tissues in adult mammals have been adequately and repeatedly reviewed (1-3) and will be mentioned here only insofar as they impinge upon developmental aspects. Macroscopically brown fat is
P. Hahn, M. Novak
openaire   +3 more sources

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