Results 31 to 40 of about 254,914 (259)

Mitochondrial dysfunction in white adipose tissue [PDF]

Trends in Endocrinology & Metabolism, 2012
Although mitochondria in brown adipose tissue and their role in non-shivering thermogenesis have been widely studied, we have only a limited understanding of the relevance of mitochondria in white adipose tissue (WAT) for cellular homeostasis of the adipocyte and their impact upon systemic energy homeostasis.
Christine M, Kusminski, Philipp E, Scherer   +1 more
openaire   +2 more sources

Pre- and postnatal adipose tissue development in farm animals: from stem cells to adipocyte physiology [PDF]

, 2016
To view supplementary material for this article, please visit http://dx.doi.org/10.1017/S1751731116000872Both white and brown adipose tissues are recognized to be differently involved in energy metabolism and are also able to secrete a variety of ...
Bonnet, Muriel, Gondret, Florence, Louveau, Isabelle, Perruchot, Marie-Hélène   +3 more
core   +3 more sources

Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming [PDF]

, 2017
BACKGROUND: The de novo biosynthesis of fatty acids (DNL) through fatty acid synthase (FASN) in adipocytes is exquisitely regulated by nutrients, hormones, fasting, and obesity in mice and humans. However, the functions of DNL in adipocyte biology and in
Czech, Michael P, Danai, Laura V, Guilherme, Adilson, Henchey, Elizabeth, Henriques, Felipe S, Jung, DaeYoung, Kim, Jason K, Lodhi, Irfan J, Pedersen, David J, Semenkovich, Clay F, Shen, Yuefei, Yenilmez, Batuhan   +11 more
core   +7 more sources

Lytic cocktail: An effective method to alleviate severe burn induced hyper-metabolism through regulating white adipose tissue browning

Heliyon, 2022
Background: Browning of white adipose tissue is associated with elevated resting metabolic rates and is considered to be one of the indispensable causes of hypermetabolism in burn patients.
Meng Zhang, Peilang Yang, Tianyi Yu, Martin C. Harmsen, Min Gao, Dan Liu, Yan Shi, Yan Liu, Xiong Zhang   +8 more
doaj   +1 more source

Hypoxia and adipose tissue function and dysfunction in obesity [PDF]

, 2013
The rise in the incidence of obesity has led to a major interest in the biology of white adipose tissue. The tissue is a major endocrine and signalling organ, with adipocytes, the characteristic cell type, secreting a multiplicity of protein factors ...
Di Girolamo M, Hales CN, Himms-Hagen J, Kyrou I, Matsumoto S, Mise H, Ostlund RE, Paul Trayhurn, Pérez de Heredia F, Trayhurn P, Wang GL, World Health Organisation, Yokota T   +12 more
core   +1 more source

Sulforaphane induces adipocyte browning and promotes glucose and lipid utilization [PDF]

, 2016
Scope: Obesity is closely related to the imbalance of white adipose tissue storing excess calories, and brown adipose tissue dissipating energy to produce heat in mammals.
Bao, Yong P., Chen, Fen, Chen, Shi Y, Fu, Jian F, Shan, Yu J, Wang, An S, Yao, An J, Zhang, Hui Q, Zhang, Xiao H, Zhao, Jin S, Zhou, Zu Q   +10 more
core   +1 more source

miR-34a-/- mice are susceptible to diet-induced obesity [PDF]

, 2016
Objective: MicroRNA (miR)−34a regulates inflammatory pathways, and increased transcripts have been observed in serum and subcutaneous adipose of subjects who have obesity and type 2 diabetes.
Baker, Andrew H., Caslake, Muriel, Collier, Andrew, Donnelly, Iona, Holmes, William, Kurowska-Stolarska, Mariola, Lavery, Christopher A., Miller, Ashley M.   +7 more
core   +1 more source

Calcium sensing receptor as a novel mediator of adipose tissue dysfunction: mechanisms and potential clinical implications

Frontiers in Physiology, 2016
Obesity is currently a serious worldwide public health problem, reaching pandemic levels. For decades, dietary and behavioral approaches have failed to prevent this disease from expanding, and health authorities are challenged by the elevated prevalence ...
Roberto Bravo, Roberto Bravo, Pamela Mattar, Pamela Mattar, Ximena Diaz, Sergio Lavandero, Sergio Lavandero, Sergio Lavandero, Mariana Cifuentes   +8 more
doaj   +1 more source

The corticotrophin-releasing factor/urocortin system regulates white fat browning in mice through paracrine mechanisms [PDF]

, 2015
Objectives: The corticotrophin-releasing factor (CRF)/urocortin system is expressed in the adipose tissue of mammals, but its functional role in this tissue remains unknown.
Clark, S., Contarino, A., Cota, D., Diz-Chaves, Y., Fanelli, F., Grammatopoulos, Dimitris, Lehnert, Hendrik, Lu, B., Markovic, Danijela, Penicaud, L., Tabarin, A.   +10 more
core   +3 more sources

Beige Adipose Tissue Identification and Marker Specificity—Overview

Frontiers in Endocrinology, 2021
Adipose tissue (AT) is classified based on its location, physiological and functional characteristics. Although there is a clear demarcation of anatomical and molecular features specific to white (WAT) and brown adipose tissue (BAT), the factors that ...
Anna-Claire Pilkington, Henry A. Paz, Henry A. Paz, Umesh D. Wankhade, Umesh D. Wankhade   +4 more
doaj   +1 more source