Results 221 to 230 of about 4,320,312 (250)

Continuous intake of Trehalose induces white adipose tissue Browning and Enhances energy metabolism. [PDF]

Nutr Metab (Lond), 2019
Arai C, Arai N, Arai S, Yoshizane C, Miyata S, Mizote A, Suyama A, Endo S, Ariyasu T, Mitsuzumi H, Ushio S.   +10 more
europepmc   +1 more source

After delivery: How recipient cells shape the fate and function of transplanted mitochondria

Clinical and Translational Medicine, Volume 16, Issue 10, October 2026.
Recipient‐cell handling shapes how transplanted mitochondria contribute after delivery, linking donor competence, recipient state and exposure duration to intracellular fate. The framework matches transient rescue, sustained functional support and durable mitochondrial DNA correction to the evidence and product attributes required for each therapeutic ...
Zhi‐Yuan Zhang, Bo‐Quan Qin, Shi‐Zhou Wu, Hui Zhang   +3 more
wiley   +1 more source

Tritrophic Interactions and Parasitoid Community Structure of Gall‐Inducing Herbivores in Arid Desert Ecosystems of Northern Xinjiang, China

Ecology and Evolution, Volume 16, Issue 10, October 2026.
This study systematically elucidates the complex tritrophic networks among the keystone shrub Lycium ruthenicum, three gall‐inducing pests, and 13 associated parasitoid species in the arid desert ecosystems of northern Xinjiang, China, reporting the globally novel stem gall‐inducing behavior of Scrobipalpa erichiodes.
Gaopeng Yu, Yuhao Nie, Caihong Gao, Hongying Hu   +3 more
wiley   +1 more source

Proteolytic Activity of Zingiber officinale Extract: Interaction With Myofibrillar Proteins of Different Origins and Functional Effects in Meat Systems

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
Ginger‐derived proteases were evaluated for their proteolytic activity toward isolated chicken and pork myofibrils and their effects during meat marination. The ginger extract showed a selective and moderate proteolytic activity, resulting in controlled protein degradation and improved meat quality, including tenderness, juiciness, flavor, and overall ...
Alessandro Crinò, Chiara Fabrizi, Andrea Menci, Katia Liburdi   +3 more
wiley   +1 more source

Role of Triceps Muscle Fiber‐Specific Myokines in Pancreatic β‐Cell Protection: Implications for Type 2 Diabetes: A Narrative Review

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aims Type 2 diabetes (T2D) is a major global health challenge, primarily driven by insulin resistance and progressive β‐cell dysfunction aggravated by chronic low‐grade inflammation. Skeletal muscle has emerged as a pivotal endocrine organ through the secretion of myokines, which exert systemic metabolic and immunomodulatory ...
Christian Tague, Dujardin Makeda, Hermann Yokolo, Joshua Ekouo   +3 more
wiley   +1 more source

Chronic, Environmentally Relevant PM2.5 Exposure Exacerbates Metabolic Dysfunction‐Associated Steatotic Liver Disease and Early‐Stage Renal Dysfunction in a Rodent Model

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 10, October 2026.
ABSTRACT While epidemiological studies link fine particulate matter (PM2.5) exposure to metabolic dysfunction‐associated steatotic liver disease (MASLD) and renal dysfunction, a translational gap exists, as most animal models utilize acute, high‐dose exposures that poorly reflect chronic, moderate‐level human scenarios.
Yi‐Siao Chen, Hugo You‐Hsien Lin, Chien‐Tzu Lin, Si‐Hua Huang, Ming‐Lun Yeh, Ming‐Lung Yu, Jin‐Ching Lee, Yao‐Chi Chung, Wei‐Ming Li, Ching‐Chia Li, Shiu‐Feng Huang, Chia‐Hung Yen   +11 more
wiley   +1 more source

Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng, Yuanyuan Shen, Ying Sun, Lu Lu, Chongkui Sun   +4 more
wiley   +1 more source

Adipocyte‐Derived KIF13B Aggravates Obesity‐Associated Metabolic Dysfunction via LRP1/PPARγ Signaling

MedComm, Volume 7, Issue 10, October 2026.
Adipocyte‐derived KIF13B promotes LRP1 localization and nuclear LRP1–PPARγ transcriptional activity, thereby enhancing adipogenic gene expression, lipid accumulation, and obesity‐associated metabolic dysfunction. Adipocyte‐specific Kif13b deletion disrupts this LRP1/PPARγ axis, suppresses adipogenic programming, reduces adipose expansion, and protects ...
Guolin Miao, Zhaoling Li, Lianxin Zhang, Yitong Xu, Ziwei Wang, Zixun Wang, Aiden Xian, Liwen Zheng, Jingxuan Chen, Yufei Han, Chunhua Shan, Kaikai Lu, Ming Tao, Ling Zhang, Weiguang Zhang, Wei Huang, Yuhui Wang, Rui Wei, Erdan Dong, Xunde Xian   +19 more
wiley   +1 more source

White adipose tissue browning preserves UCP1-dependent nonshivering thermogenesis upon brown-adipocyte specific lipase-deficiency

Manandhar Y, Pirchheim A, Hofer P, Krispel W, Vujic N, Kolb D, Schweiger M, Taschler U, Zimmermann R, Hoefler G, Kratky D, Zechner R, Schreiber R.   +12 more
europepmc   +1 more source

The Bile Acid Signaling Axis: Deciphering the Roles of FXR and TGR5 in Hepatic Steatosis, Fibrosis, and Cancer

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Bile acids (BAs) serve not only as emulsifiers for lipid digestion but also as essential signaling molecules, governing various physiological and pathological processes through their interaction with the farnesoid X receptor (FXR) and the takeda G protein‐coupled receptor 5 (TGR5).
Jie Liu, Kui Sun, Hongmei Liu, Meiyang Zhu, Chunmeng Li, Yuqi He, Lin Qin   +6 more
wiley   +1 more source