Investigation of effect of hyperinsulinaemia on adipose tissue microvasculature. [PDF]
, 2015 Background: Obesity in Qatar is amongst the highest globally and constitutes a serious health risk. Obese individuals are at greater risk of vascular disease compared to the lean, especially in the insulin resistant state.
Bakhamis, AAA
core
A combined transcriptomics and lipidomics analysis of subcutaneous, epididymal and mesenteric adipose tissue reveals marked functional differences [PDF]
, 2010 Depot-dependent differences in adipose tissue physiology may reflect specialized functions and local interactions between adipocytes and surrounding tissues.
Kelder, T.A.J. +46 more
core +3 more sources
DEPP Deficiency Contributes to Browning of White Adipose Tissue
, 2022 Decidual protein induced by progesterone (DEPP) was originally identified as a modulator in the process of decidualization in the endometrium. Here, we define that DEPP is involved in adipose tissue thermogenesis, which contributes to metabolic ...
Ying He +15 more
core +1 more source
Signals from adipose tissue in morbid obesity and effect on depot specific differences [PDF]
, 2009 Signals from adipose tissue, such as interleukin-6 (IL-6) and asymmetric dimethyl arginine (ADMA), an endogenous nitric oxide inhibitor, explain the link between obesity and metabolic diseases.
Madani, R.
core
Exercise and browning of white adipose tissue - a translational perspective
, 2020 Browning of white adipose tissue is a cold-induced phenomenon in rodents, constituted by the differentiation of a subset of thermogenic adipocytes among existing white adipocytes.
Pedersen, Bente Klarlund +2 more
core +1 more source
HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning [PDF]
, 2017 White adipose tissue (WAT) can undergo a phenotypic switch, known as browning, in response to environmental stimuli such as cold. Post-translational modifications of histones have been shown to regulate cellular energy metabolism, but their role in white
Silva, R. +41 more
core +1 more source
iMeta, EarlyView.The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
Egr1 deficiency induces browning of inguinal subcutaneous white adipose tissue in mice
, 2017 Beige adipocyte differentiation within white adipose tissue, referred to as browning, is seen as a possible mechanism for increasing energy expenditure. The molecular regulation underlying the thermogenic browning process has not been entirely elucidated.
Marianne Bléher +6 more
core +1 more source
Gut Enterococcus faecium derived leucic acid mediates the antiobesity effect of dietary fiber
iMeta, EarlyView.This study identified Enterococcus faecium as a gut bacterium with anti‐obesity activity, which alleviated adipocyte hypertrophy, dyslipidemia, and hepatic steatosis by converting leucine into leucic acid (LEA) to regulate mitochondrial oxidative phosphorylation.
Baifei Hu +9 more
wiley +1 more source
EBioMedicine, 2019 Background: Parathyroid hormone related protein (PTHrP) triggers white adipose tissue (WAT) browning and cachexia in lung cancer mouse models. It remains unknown whether excessive PTH secretion affects WAT browning and to what extent it contributes to ...
Yang He +18 more
doaj +1 more source