Results 91 to 100 of about 4,320,312 (250)

Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue

iNew Medicine, EarlyView.
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao, Jingjing Sun, Yan Lu, Ying Yang   +3 more
wiley   +1 more source

Adipose tissue-targeted drug delivery for treating obesity: current opportunities and challenges

Drug Delivery
Obesity has emerged as a global public health crisis in the 21st century, with its prevalence continuing to rise worldwide. Beyond its well-established links to metabolic diseases (diabetes, hypertension, dyslipidemia, and cardiovascular disease ...
Taimin Luo, Lei Chen, Kun Tu, Longyang Jiang, Sicheng Liang, Shurong Wang, Yilan Huang, Xuping Yang   +7 more
doaj   +1 more source

Estimation of CT-derived abdominal visceral and subcutaneous adipose tissue depots from anthropometry in Europeans, South Asians and African Caribbeans [PDF]

, 2013
Background South Asians and African Caribbeans experience more cardiometabolic disease than Europeans. Risk factors include visceral (VAT) and subcutaneous abdominal (SAT) adipose tissue, which vary with ethnicity and are difficult to quantify using ...
Willis Joseph, Hughes, AD, Ian F. Godsland (212035), Peter Whincup (20840), Peter Whincup, Tillin, T, Therese Tillin, Joseph Willis, Sophie V. Eastwood (459934), Tillin Therese, Andrew Wright (459935), Nita Forouhi (459938), Nita Forouhi, Andrew Wright, Joseph Willis (459937), Eastwood Sophie V., Nishi Chaturvedi, Wright, A, Forouhi, N, Ian F Godsland, Nishi Chaturvedi (130777), Hughes Alun D., Eastwood, SV, Wright Andrew, Chaturvedi, N, Whincup, P, John Heasman (459936), Whincup Peter, Godsland, IF, Chaturvedi Nishi, Sophie V Eastwood, Alun D Hughes, Heasman John, Heasman, J, John Heasman, Forouhi Nita, Willis, J, Alun D. Hughes (395075), Therese Tillin (130770), Godsland Ian F.   +39 more
core   +1 more source

Bisphenol M Induces Dose‐Dependent Hepatic Injury and Fibrotic Remodeling in Female Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The safety of bisphenol analogs as alternatives to bisphenol A (BPA) is increasingly concerning. This study investigated the hepatotoxic effects of bisphenol M (BPM), a widely used BPA substitute, in 6‐week‐old female BALB/c mice exposed to 2.5, 5, and 10 mg/kg/day intraperitoneally for 14 days. Hepatic changes were assessed via histopathology,
Muhammed Canik, Asuman Deveci Ozkan, Tuğba Kotil, Nazan Deniz Yön   +3 more
wiley   +1 more source

The DMHGABA Neurons Play a Crucial Role in the Regulation of Cold‐Induced White Adipose Browning through DMH to LPO Projection

Advanced Science
The browning of white adipose tissue (WAT) can convert energy‐storing WAT into energy‐dissipating beige adipose tissue to combat obesity and metabolic dysfunction. Cold exposure is a WAT browning‐inducing condition in mice.
Zhijie Su, Yujia Hou, Bingwei Wang, Qian Zhou, Wen Yang, Bingbing Guo, Chenyu Zhang, Miao Zhao, Xiaoning Yang, Jiarui Liu, Xiangyang Xie, Lihua Qin, Weiguang Zhang, Wei L. Shen, Ruimao Zheng   +14 more
doaj   +1 more source

Hyperactive browning and hypermetabolism: potentially dangerous element in critical illness

Frontiers in Endocrinology
Brown/beige adipose tissue has attracted much attention in previous studies because it can improve metabolism and combat obesity through non-shivering thermogenesis.
Lu Huang, Lili Zhu, Zhenxiong Zhao, Shenglu Jiang   +3 more
doaj   +1 more source

What Fat Is That? Scanning Perirenal Fat: A Survey of Australasian Sonographers

Journal of Medical Radiation Sciences, EarlyView.
What fat is that? Ultrasound measurement of perirenal adipose tissue and CVD. Results of a survey of Australasian sonographers 2024. ABSTRACT Introduction Ultrasound measures of perirenal adipose tissue (PRAT) have emerged as potentially efficient, cost‐effective, and accessible methods for assessing cardiovascular disease (CVD) risk.
Victoria Baumann, Richard Banati, Jillian Clarke   +2 more
wiley   +1 more source

MiR-27b-3p Inhibition Enhances Browning of Epididymal Fat in High-Fat Diet Induced Obese Mice

Frontiers in Endocrinology, 2019
Objective: Long-term dysregulation of energy balance is the key component of the obesity epidemic. Given the harm of central obesity and the discovery that beige cells appear within white adipose tissue (WAT), enhancing the energy-expending or “browning”
Jing Yu, Yifan Lv, Fengliang Wang, Xiaocen Kong, Wenjuan Di, Juan Liu, Yunlu Sheng, Shan Lv, Guoxian Ding   +8 more
doaj   +1 more source

Browning of Adipose Tissue and Sirtuin1 Involvement.

, 2018
Obesity is an important risk factor for many diseases, including cardiovascular diseases, metabolic syndrome and cancers. Excessive dietary intake of caloric food results in its accumulation in white adipose tissue (WAT), whereas energy expenditure by ...
Rezzani R., Krajčíková K, Bonomini F., Favero G., Tomečková V., Rodella L. F.   +5 more
core  

Browning of white adipose tissue by melatonin [PDF]

, 2015
There are two distinct types of adipose tissue which have different functions within the body, white (WAT) and brown (BAT). Browning of WAT occurs with increases in the WAT sympathetic nervous system (SNS) drive.
Zarebidaki, Eleen
core   +1 more source