Results 121 to 130 of about 4,082 (209)

Ring A structural modified derivatives of withaferin A and the evaluation of their cytotoxic potential

, 2011
Regio-/stereoselective Michael addition to ring A of withaferin-A was performed using an optimized reaction procedure to synthesise a library of 2,3-dihydro,3- -substituted withaferin-A derivatives. The analogues thus obtained were evaluated for in vitro
Debaraj Mukherjee, Saxsena, A.K., Rabiya Majeed, Yousuf, Syed Khalid, Syed Khalid Yousuf, Majeed, Rabiya, Purnima, Basant, K.A. Suri, Sangwan, Payare lal, Payare lal Sangwan, Ahmad, Mudassier, Taneja, Subhash Chandra, Suri, K.A., Mukherjee, Debaraj, Mudassier Ahmad, A.K. Saxsena, Basant Purnima, Subhash Chandra Taneja   +17 more
core   +1 more source

Protective role of Withaferin-a on red blood cell integrity during 7,12-dimethylbenz[A]anthracene induced oral carcinogenesis

, 2010
The aim of the present study was to investigate the protective effect of Withaferin-A on red blood cell integrity during 7,12-dimethylbenz[a]anthracene (DMBA) induced oral carcinogenesis.
Vellaichamy, J, L Alias, K Rajalingam, Panjamurthy, K, Rajalingam, K, Alias, L, K Panjamurthy, P Pugalendi, J Vellaichamy, Manoharan, S, S Balakrishnan, Balakrishnan, S, S Manoharan, Pugalendi, P   +13 more
core   +1 more source

Withaferin a suppresses the expression of vascular endothelial growth factor in ehrlich ascites tumor cells via sp1 transcription factor

, 2009
In the ayurvedic system of medicine, the medicinal plant, Withania somnifera Dunal (Solanaceae) finds application for numerous ailments including cancer.
Bharathi P. Salimath, Prasanna Kumar, S., Shilpa, P.   +2 more
core  

Combinatorial phenethyl isothiocyanate and withaferin A targets multiple epigenetics pathways to inhibit MCF-7 and MDA-MB-231 human breast cancer cells

Cancer Cell International
Background Epigenetic phytochemicals are considered as an efficacious and safe alternative to synthetic drugs in drug discovery. In this regard, combinatorial interventions enable simultaneously targeting various neoplastic pathways to eradicate multiple
Mohammad Mijanur Rahman, Trygve O. Tollefsbol   +1 more
doaj   +1 more source

New Vistas for Withania somnifera in Signal Transduction of Inflammation and Aging. [PDF]

Pharm Res
Sharma E, Mehta D, Muthuraj P, Panda S, Ajgaonkar S, Maniar D, Biju A, Nair S.   +7 more
europepmc   +1 more source

Combined Effects of Withaferin A and Sodium Butyrate on NF-κB Signaling and Epigenetic Regulation in Breast Cancer Cells. [PDF]

Nutrients
Witt BL, Singaravelan N, Tollefsbol TO.
europepmc   +1 more source

Molecular docking analysis of DprE1 from <i>M. tuberculosis</i> with phytochemicals. [PDF]

Bioinformation
Raja J, Blessy JJ.
europepmc   +1 more source

Withaferin A, a candidate drug for lupus nephritis, confers renal protection via Pon1‑mediated attenuation of oxidative stress. [PDF]

Int J Mol Med
Xue M, Feng J, Mao X.
europepmc   +1 more source

DFT supported computational insights into Withaferin A structure and its binding interaction with Hsp90. [PDF]

Sci Rep
Shoni R, Karki PR, Tripathi K.
europepmc   +1 more source

Oral Administration of Withaferin A Increases Infiltration of CD4⁺ Helper T Cells in a Mouse Model of Mammary Tumor. [PDF]

J Cancer Prev
Hahm ER, Singh KB, Singh SV.
europepmc   +1 more source