Effects of Withania somnifera on Zebrafish
Withania somnifera (commonly known as Ashwagandha), is a plant in which its root powder is sold as a dietary supplement. It is being commonly used as an anti-anxiety supplement to combat stress.
Bekhtyar, Diyari
core
Phyto physico-chemical profile of Ashwagandha (Withania somnifera Dunal)
Introduction: The present article deals with study of phytochemical analysis of Withania somnifera Dunal roots. Ashwagandha (Withania somnifera Dunal - Solanaceae), The use of Ashwagandha (WS) is increasing due to a number of chemical constituents ...
Dr. Bargale Sushant Sukumar +2 more
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Ashwagandha: Is It Safe? Part 1: A Regulatory Review
ABSTRACT Over the last decade, ashwagandha (Withania somnifera (L.) Dunal, AS) has been brought under increasing scrutiny by EU regulators regarding its safety for the use in food supplements, culminating in a recent recommendation for an Article 8 procedure according to Regulation (EC) No. 1925/2006 in the European Union (EU).
T. Brendler +5 more
wiley +1 more source
De novo assembly, functional annotation and comparative analysis of Withania somnifera leaf and root transcriptomes to identify putative genes involved in the withanolides biosynthesis. [PDF]
Withania somnifera is one of the most valuable medicinal plants used in Ayurvedic and other indigenous medicine systems due to bioactive molecules known as withanolides.
Parul Gupta +7 more
doaj +1 more source
Chlorinated Withanolides from Withania somnifera [PDF]
A chlorinated withanolide, 6α-chloro-5β,17α-dihydroxywithaferin A (1), and nine known withanolides, 6α-chloro-5β-hydroxywithaferin A (2), (22R)-5β-formyl-6β,27-dihydroxy-1-oxo-4-norwith-24-enolide, withaferin A, 2,3-dihydrowithaferin A, 3-methoxy-2,3 ...
Timmermann, Barbara N. +5 more
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Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley +1 more source
Proximate Nutritive Values and Mineral Components of Withania Somnifera (Linn.) Dunal
Withania somnifera (Linn.) Dunal is a subtropical shrub with important medicinal properties. The nutritive value and the elemental composition of different parts of plants, Withania somnifera which are grown in two distinct geographical regions ...
S. R. Krishnamurthy, P. Sarala
doaj +1 more source
Reciprocal loss of CArG-boxes and auxin response elements drives expression divergence of MPF2-Like MADS-box genes controlling calyx inflation. [PDF]
Expression divergence is thought to be a hallmark of functional diversification between homologs post duplication. Modification in regulatory elements has been invoked to explain expression divergence after duplication for several MADS-box genes, however,
Muhammad Ramzan Khan +2 more
doaj +1 more source
Safety Evaluation of an Aqueous Root and Leaf Extract of Ashwagandha (Withania somnifera)
Sensoril, an aqueous root and leaf extract of ashwagandha showed no evidence of mutagenicity in the in vitro Ames assay, was negative in the in vitro micronucleus, in vivo mammalian bone marrow chromosome aberration assays, and was well tolerated in the rat at up to 4000 mg/kg BW/day when administered orally for a period of 90 days. The data from these
Mukesh Summan +2 more
wiley +1 more source
The present study reports an efficient protocol for indirect shoot organogenesis and plantlets regeneration of Withania somnifera (L.) Dunal. Leaf explants were cultured on Murashige and Skoog (MS) medium supplemented with different concentrations and ...
D. Chakrabarty +4 more
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