Results 181 to 190 of about 3,164 (224)

Biosynthesis of the triterpenoid withanolides in Withania somnifera

Current Opinion in Plant Biology
Ashwagandha (Withania somnifera L. Dunal) is a versatile medicinal plant of Solanaceae family, renowned for its potent therapeutic properties, due to which it is extensively used in Indian traditional systems of medicine such as Ayurveda. The medicinal properties are attributed to specialized metabolites known as withanolides, which are chemically ...
Ananth Krishna Narayanan, Dinesh A. Nagegowda   +1 more
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Withanolides from Physalis hispida

Journal of Natural Products, 2014
Nine new withanolides (1-9), withahisolides A-I, were isolated along with nine known compounds (10-18) from the aerial parts of Physalis hispida. The structures of 1-9 were elucidated through a variety of spectroscopic techniques, while the structures of 1 and 2 were confirmed by X-ray crystallographic analysis. Compounds 1-3 are the first withanolides
Cong-Mei, Cao, Huaping, Zhang, Robert J, Gallagher, Victor W, Day, Kelly, Kindscher, Patrick, Grogan, Mark S, Cohen, Barbara N, Timmermann   +7 more
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Withanolides from Ajuga parviflora

Journal of Natural Products, 1999
Two new withanolides named ajugin A [14alpha,20, 28-trihydroxy-1-oxo-(20R,22R)-witha-3,5,24-trienolide] (1) and ajugin B [14alpha,20,27-trihydroxy-1-oxo-(20R,22R)-witha-5, 24-dienolide] (2) were isolated from the whole plant of Ajuga parviflora, and their structures were deduced by NMR and MS analyses.
, Khan, , Malik, , Ahmad, , Nawaz
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Cytotoxic withanolides from Acnistus arborescens

Phytochemistry, 2002
Three cytotoxic withanolides, two with new structures, were isolated from the leaves of Acnistus arborescens and their structures determined by a combination of 1D and 2D NMR, mass spectral, and molecular modeling studies. Dereplication analysis of the ethyl ether extract was useful for evaluating the components showing significant cytotoxic activity.
Sandro, Minguzzi, Lauro E S, Barata, Young Geun, Shin, Patrick F, Jonas, Hee Byung, Chai, Eun Jung, Park, John M, Pezzuto, Geoffrey A, Cordell   +7 more
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Antiproliferative Withanolides from Jaborosa Riojana

Fitoterapia
Six previously undescribed withanolides, of which three had a normal glycosylated skeleton (Jaborosalactones 49-51) and three had a sativolide skeleton (12-O-methyl jaborosalactone 52, jaborosalactone 53, and 12-O-methyl jaborosalactone 53), were isolated from the aerial parts of Jaborosa riojana.
Lobatto, Virginia Laura, Casero, Carina Noelia, González Bakker, Aday, Padrón, José M., Nicotra, Viviana Estela   +4 more
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Withanolides from Withania adpressa

Helvetica Chimica Acta, 2007
AbstractFrom the leaves of Withania adpressa, a plant endemic to Sahara of Morocco and Algeria, the novel steroidal lactone (22R)‐14α,15α,17β,20β‐tetrahydroxy‐1‐oxowitha‐2,5,24‐trien‐26,22‐olide (= (15S,17S)‐14,15,17,20‐tetrahydroxy‐22,26‐epoxyergosta‐2,5,24‐triene‐1,26‐dione; 1), was isolated, along with three known compounds, withanolides F (2), J (3)
Abdeljebbara, Lalla Hasna, Humam, Munir, Christen, Philippe, Jeannerat, Damien, Vitorge, Bruno, Amzazi, Saaid, Benjouad, Abdelaziz, Hostettmann, Kurt, Bekkoucheb, Khalid   +8 more
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Withanolides from Withania somnifera roots

Phytochemistry, 2008
Two new and seven known withanolides along with beta-sitosterol, stigmasterol, beta-sitosterol glucoside, stigmasterol glucoside, alpha+beta glucose were isolated from the roots of Withania somnifera. Among the known compounds, Viscosa lactone B, stigmasterol, stigmasterol glucoside and alpha+beta glucose are being reported from the roots of W ...
Laxminarain, Misra, Priyanka, Mishra, Archana, Pandey, Rajender S, Sangwan, Neelam S, Sangwan, Rakesh, Tuli   +5 more
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Withanolide glycosides from dunalia australis*

Phytochemistry, 1992
Four new withanolide glycosides, (20R,22R)-O-(3)-[beta-D- xylopyranosyl(1----3), beta-D-xylopyranosyl(1----4)]-beta-D-glucopyranosyl-3 beta,20-dihydroxy-1 alpha-acetoxy-witha-5,24-dienolide, (20R,22R)-O-(3)-[beta-D-xylopyranosyl(1----3), beta-D-glucopyranosyl(1----4)]-beta-D-glucopyranosyl-3 beta,20-dihydroxy-1 alpha-acetoxy-witha-5,24-dienolide, (20R ...
M, Lischewski, N T, Hang, A, Porzel, G, Adam, G, Massiot, C, Lavaud   +5 more
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Withanolides from Salpichroa origanifolia

Journal of Natural Products, 2001
Five new withanolides, 5 alpha,6 alpha:22,26:24,25-triepoxy-16 alpha,26-dihydroxy-18(13-->17)-abeo-ergosta-2,13-dien-1-one (salpichrolide N, 1), 5 alpha,6 alpha:22,26:24,25-triepoxi-15 alpha,26-dihydroxyergosta-2,16-dien-1-one (salpichrolide L, 2), 5 alpha,6 alpha:22,26-diepoxi-24,25,26-trihydroxy-17(13-->18)-abeo-ergosta-2,13,15,17-tetraen-1-one ...
M C, Tettamanzi, A S, Veleiro, J R, de la Fuente, G, Burton   +3 more
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Withanolides: Promising candidates for cancer therapy

Phytotherapy Research
AbstractNatural products have played a significant role throughout history in the prevention and treatment of numerous diseases, particularly cancers. As a natural product primarily derived from various medicinal plants in the Withania genus, withanolides have been shown in several studies to exhibit potential activities in cancer treatment ...
Qiang Zhang, YongKang Yuan, Shijie Cao, Ning Kang, Feng Qiu   +4 more
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