Results 161 to 170 of about 3,164 (224)
Sub-functionalization and epigenetic regulation of a biosynthetic gene cluster in Solanaceae
Priego-Cubero S +8 more
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Withanolide Z, a New Chlorinated Withanolide fromWithania somnifera [PDF]
Reverse-phase preparative HPLC analysis of the n-butanol fraction of the methanolic extract of Withania somnifera Dunal (leaves) afforded a novel chlorinated withanolide, namely withanolide Z (1), along with four known withanolides, withanolide B (2), withanolide A (3), 27-hydroxywithanolide B (4) and withaferin A (5).
Swapan, Pramanick +4 more
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Natural withanolides, an update
Natural Product Reports, 2022This review summarizes the research progress on the structural classification, biological activities and mechanisms, metabolism and pharmacokinetic investigations, biosynthesis, and synthesis and structural modifications of the withanolides.
Gui-yang Xia +3 more
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Withanolides from Discopodium penninervium
Fitoterapia, 2023Discopodium penninervium is a medicinal plant endemic to Ethiopia. Its twigs extract led to the isolation of three new withanolides, discopodinolides A - C, and four known analogues. The structures of the compounds were elucidated using NMR, HRMS data analyses, and literature data.
Kibrom Gebreheiwot, Bedane +2 more
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Natural withanolides: an overview
Natural Product Reports, 2011Withanolides are a group of naturally occurring C28 steroids built on an ergostane skeleton functionalized at carbons 1, 22 and 26, commonly known as the withanolide skeleton. Over the period of August 1996 to March 2010, 360 new naturally occurring withanolides were isolated and identified.
Li-Xia, Chen, Hao, He, Feng, Qiu
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Trypanocidal Withanolides and Withanolide Glycosides from Dunalia brachyacantha
Journal of Natural Products, 2001Two new withanolide glycosides, (20R,22R)-O-(3)-alpha-L-rhamnopyranosyl(1-->4)-beta-D-glucopyranosyl-1 alpha,12 beta-diacetoxy-20-hydroxywitha-5,24-dienolide (3) and (20R,22R)-O-(3)-beta-D-xylopyranosyl(1-->3)-[beta-D-xylopyranosyl(1-->4)]-beta-D-glucopyranosyl-1 alpha-acetoxy-12 beta,20-dihydroxywitha-5,24-dienolide (4), were isolated from the leaves ...
J A, Bravo B +7 more
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