Results 201 to 210 of about 459,861 (330)

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Porcine <i>FRZB</i> (sFRP3) Negatively Regulates Myogenesis via the Wnt Signaling Pathway. [PDF]

Animals (Basel)
Nie J, Fu Y, Hao X, Yan D, Zhang B, Zhang H.   +5 more
europepmc   +1 more source

Discovery of Inhibitors of the Wnt and Hedgehog Signaling Pathways through the Catalytic Enantioselective Synthesis of an Iridoid‐Inspired Compound Collection [PDF]

, 2013
Hiroshi Takayama, Zhi‐Jun Jia, Lea Kremer, Jonathan O. Bauer, Carsten Strohmann, Slava Ziegler, Andrey P. Antonchick, Herbert Waldmann   +7 more
openalex   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Genome-wide identification and expression analysis of Wnt gene family in the forest musk deer (Moschus berezovskii) under musk secretion stage. [PDF]

BMC Genomics
Gu YJ, Sun JT, Dan F, Jiang XM, Liao DD, Yao CX, Qi WH.   +6 more
europepmc   +1 more source

Characterization of the molecular functions of Armadillo, Legless and Pygopus in nuclear Wingless/Wnt signalling

, 2006
Raymond Hoffmans
openalex   +1 more source

WNT Signaling and Lymphocyte Development [PDF]

, 2002
Marc van de Wetering, Wim de Lau, Hans Clevers   +2 more
openalex   +1 more source

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

SMAD7 regulates the canonical Wnt signaling through TGF-β cascade crosstalk and SMAD7/β-CATENIN transcription factor complex formation during tooth regeneration. [PDF]

Int J Oral Sci
Chen Q, Liu Z, Zhou B, Liang C, Chen Y, Tian W, Chen T.   +6 more
europepmc   +1 more source

Preventing WNT signalling [PDF]

Nature Reviews Molecular Cell Biology, 2012
openaire   +2 more sources