Results 81 to 90 of about 5,637 (202)
Wwox and Ap2γ Expression Levels Predict Tamoxifen Response [PDF]
Clinical Cancer Research, 2007 Abstract Purpose: Assessment of expression levels of Wwox, Wwox-interacting proteins Ap2α, Ap2γ, and ErbB4, the Ap2γ transcriptional target protein Her2, and the possible Ap2α transcriptional target PrkaRIα, in breast cancers, to determine their roles in tamoxifen resistance.
Guler, Gulnur +5 more
openaire +3 more sources
Gene expression profiling of meningiomas: current status after a decade of microarray-based transcriptomic studies [PDF]
, 2011 Purpose This article provides a review of the transcriptomic expression profiling studies that have been performed on meningiomas so far. We discuss some future prospects and challenges ahead in the field of gene expression profiling.
Mads Aarhus +2 more
core +2 more sources
Translational Neuroscience, 2018 The WWOX gene has a WW domain containing oxidoreductase, which is located at the common fragile site FRA16D at chromosome 16q23. WWOX is a tumor suppressor gene that has been associated with several types of cancer such as hepatic, breast, lung, prostate,
Ehaideb Salleh N. +4 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2019 The brain is the most functionally organized structure of all organs. It manages behavior, perception and higher cognitive functions. The WWOX gene is non-classical tumor suppressor gene, which has been shown to have an impact on proliferation, apoptosis
Katarzyna Kośla +5 more
doaj +1 more source
Phosphoenolpyruvate carboxykinase maintains glycolysis-driven growth in Drosophila tumors [PDF]
, 2017 Published online: 14 September 2017Tumors frequently fail to pass on all their chromosomes correctly during cell division, and this chromosomal instability (CIN) causes irregular aneuploidy and oxidative stress in cancer cells.
Gregory, S. +4 more
core +3 more sources
WWOX drives UV/cold shock‐induced bubbling cell death whereas without WWOX cells pop out
The FASEB Journal, 2019 Bubbling cell death (BCD) is known as release of an enlarging nuclear bubble from the surface of each cell at room temperature or lower post exposure of the cells to UV irradiation and cold shock. BCD concerns the severity of frostbite and UV. However, the molecular mechanism is largely unknown.
Nan‐Shan Chang +2 more
openaire +1 more source
BcCluster: a bladder cancer database at the molecular level [PDF]
, 2016 Background: Bladder Cancer (BC) has two clearly distinct phenotypes. Non-muscle invasive BC has good prognosis and is treated with tumor resection and intravesical therapy whereas muscle invasive BC has poor prognosis and requires usually systemic ...
Bhat, Akshay +5 more
core +3 more sources
Human Mutation, Volume 2026, Issue 1, 2026.To develop a personalized neoantigen therapy strategy for microsatellite stability (MSS)–advanced colorectal cancer (CRC), neoantigens from collected human CRC samples were screened, and the feasibility and effectiveness of these neoantigens in treating CRC were explored.
Dajiang Li +8 more
wiley +1 more source
Frontiers in Neuroscience, 2023 IntroductionGlioblastoma (GBM) is notorious for its clinical and molecular heterogeneity, contributing to therapeutic failure and a grim prognosis. WWOX is one of the tumor suppressor genes important in nervous tissue or related pathologies, which was ...
Żaneta Kałuzińska-Kołat +4 more
doaj +1 more source
Hypoxic conditions differentially regulate TAZ and YAP in cancer cells [PDF]
, 2014 The Hippo-YAP pathway is altered and implicated as an oncogenic signaling pathway in many human cancers. Hypoxia is an important microenvironmental factor that promotes tumorigenesis.
Cai, Qingchun, Xu, Yan, Yan, Libo
core +1 more source