Results 91 to 100 of about 2,696,015 (152)

A role for the WWOX gene in prostate cancer

, 2006
Expression of the WWOX gene, encompassing the common chromosome fragile site FRA16D, is altered in a large fraction of cancers of various types, including prostate cancer.
ILIOPOULOS D, FABBRI M, DRUCK T, KLEIN RD, SEMBA S, MORRISON CD, CROCE CM, QIN HR, HUEBNER K., VOLINIA, Stefano   +9 more
core  

Data_Sheet_4_The WWOX Gene Influences Cellular Pathways in the Neuronal Differentiation of Human Neural Progenitor Cells.PDF

, 2019
The brain is the most functionally organized structure of all organs. It manages behavior, perception and higher cognitive functions. The WWOX gene is non-classical tumor suppressor gene, which has been shown to have an impact on proliferation, apoptosis
Katarzyna Kośla (6688535), Magdalena Orzechowska (4640353), Andrzej K. Bednarek (4640356), Elżbieta Płuciennik (6688541), Ewa Styczeń-Binkowska (7329143), Magdalena Nowakowska (3549914)   +5 more
core   +1 more source

Data_Sheet_3_The WWOX Gene Influences Cellular Pathways in the Neuronal Differentiation of Human Neural Progenitor Cells.pdf

, 2019
The brain is the most functionally organized structure of all organs. It manages behavior, perception and higher cognitive functions. The WWOX gene is non-classical tumor suppressor gene, which has been shown to have an impact on proliferation, apoptosis
Katarzyna Kośla (6688535), Magdalena Orzechowska (4640353), Andrzej K. Bednarek (4640356), Elżbieta Płuciennik (6688541), Ewa Styczeń-Binkowska (7329143), Magdalena Nowakowska (3549914)   +5 more
core   +1 more source

Common chromosomal fragile site FRA16D tumor suppressor WWOX gene expression and metabolic reprograming in cells

, 2013
The WWOX gene spans the FRA16D common chromosomal fragile site and is able to suppress tumor growth. FRA16D is a frequent site of DNA instability in cancer resulting in reduced levels of WWOX expression.
Amanda Choo, Dayan, S., Richards, R., Robert I. Richards, O'Keefe, L., Choo, A., Sonia Dayan, Louise V. O'Keefe   +7 more
core   +1 more source

Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma

, 2007
We performed FISH for 16q23 abnormalities in 861 patients with newly diagnosed multiple myeloma and identified del(16q) in 19.5%. In 467 cases in which demographic and survival data were available, del(16q) was associated with a worse overall survival ...
Dagrada, G.P., Dickens, N.J., Nightingale, M., Dachs Cabanas, Elisabet, Stockley, David, Morgan, G.J., Cross, Nicholas C.P., Davies, Faith E., Johnson, D.C., Morgan, Gareth J., Cross, N.C.P., Jenner, Matthew W., Leone, P.E., Stockley, D., Jenner, M.W., Protheroe, R.K.M., Davies, F.E., Chiecchio, Laura, Gonzalez, D., Else, Monica, Protheroe, R.K., Leone, Paola E., Ross, F.M., Ross, Fiona M., Dagrada, Gian Paolo, Dickens, Nicholas J., Protheroe, Rebecca K.M., Johnson, David C., Dachs Cabanas, E., Gonzalez, David, Nightingale, Mathew, Chiecchio, L., Walker, B.A., Cross, N.C., Else, M., Walker, Brian A.   +35 more
core   +1 more source

Wwox-KO BK5-Cre transgenic mice model gene expression profile study.

, 2012
(A) Heatmap of the differentially expressed genes between Wwox WT vs.
Xinsheng Gao (167498), C. Marcelo Aldaz (167521), Fernando Benavides (29259), Martin C. Abba (167514), Brent W. Ferguson (167494), Jaeho Lee (167509), Hyunsuk Kil (167504)   +6 more
core   +1 more source

The WWOX gene in brain development and pathology. [PDF]

Exp Biol Med (Maywood), 2020
Kośla K, Kałuzińska Ż, Bednarek AK.
europepmc   +1 more source

Tumor suppressive functions of WWOX.

, 2016
WWOX interacts with signaling molecules in the cytoplasm and prevents their entry to the nucleus to modulate their tumorigenic pathways. Upon stress such as ionizing radiation (IR), ultraviolet radiation (UV), or maybe even neuronal injury, WWOX enters ...
Thomas G. Hofmann (196333), Idit Hazan (233559), Rami I. Aqeilan (480672)   +2 more
core   +1 more source

Genome-wide identification and functional validation of the WW domain containing oxidoreductase gene associated with sleep duration

Scientific Reports
Individual differences in sleep duration have been reported, and genetic components of sleep duration have been identified showing various heritability.
Soriul Kim, So Who Kang, Song E. Kim, Hyeon Jin Kim, Sol Ah Kim, Yae Won Lee, Eun Young Kim, Chol Shin, Hyang Woon Lee   +8 more
doaj   +1 more source

Data_Sheet_2_The WWOX Gene Influences Cellular Pathways in the Neuronal Differentiation of Human Neural Progenitor Cells.PDF

, 2019
The brain is the most functionally organized structure of all organs. It manages behavior, perception and higher cognitive functions. The WWOX gene is non-classical tumor suppressor gene, which has been shown to have an impact on proliferation, apoptosis
Katarzyna Kośla (6688535), Magdalena Orzechowska (4640353), Andrzej K. Bednarek (4640356), Elżbieta Płuciennik (6688541), Ewa Styczeń-Binkowska (7329143), Magdalena Nowakowska (3549914)   +5 more
core   +1 more source