Results 71 to 80 of about 2,696,015 (152)

WWOX Phosphorylation, Signaling, and Role in Neurodegeneration

Frontiers in Neuroscience, 2018
Homozygous null mutation of tumor suppressor WWOX/Wwox gene leads to severe neural diseases, metabolic disorders and early death in the newborns of humans, mice and rats.
Chan-Chuan Liu, Chan-Chuan Liu, Pei-Chuan Ho, I.-Ting Lee, Yu-An Chen, Chun-Hsien Chu, Chih-Chuan Teng, Sheng-Nan Wu, Chun-I. Sze, Chun-I. Sze, Ming-Fu Chiang, Nan-Shan Chang, Nan-Shan Chang, Nan-Shan Chang, Nan-Shan Chang   +14 more
doaj   +1 more source

Epidemiology of progressive intellectual and neurological deterioration in UK children

Developmental Medicine &Child Neurology, Volume 68, Issue 3, Page 418-428, March 2026.
This study of PIND in UK children was carried out via the British Paediatric Surveillance Unit from 1997 to 2024. It identified six cases of vCJD. 2367 children had other diagnoses explain their deterioration. There were 259 other diseases in the diagnosed group.
Christopher M. Verity, Polly J. Maunder, Anne Marie Winstone, Suvankar Pal   +3 more
wiley   +1 more source

The insider's perspective: The intracellular complosome and immune cell dynamics in cancer

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
Intracellular complement (complosome) shapes the tumour immune microenvironment. Complosome's role in cancer is underrecognised yet central to tumour immunity. C3/C5‐driven complosome signals rewire T‐cell activation, fate and metabolism. Complosome activity can promote pro‐tumour immune cell function.
Alexandra Bennion, Joanne Lysaght, Niamh Lynam‐Lennon   +2 more
wiley   +1 more source

WWOX protein expression varies among ovarian carcinoma histotypes and correlates with less favorable outcome

BMC Cancer, 2005
Background The putative tumor suppressor WWOX gene spans the common chromosomal fragile site 16D (FRA16D) at chromosome area 16q23.3-24.1. This region is a frequent target for loss of heterozygosity and chromosomal rearrangement in ovarian, breast ...
Liu Jinsong, Godwin Andrew K, Klein-Szanto Andres JP, Page Robert, Kil Hyunsuk, Abba Martín C, Ludes-Meyers John H, Rosen Daniel G, Nunez María I, Mills Gordon B, Aldaz C Marcelo   +10 more
doaj   +1 more source

Análise molecular do gene WWOX em leucoplasia bucal [PDF]

, 2008
Leucoplasia bucal é a lesão cancerizável mais comum da cavidade bucal com índice de transformação maligna variando de 1 a 18%. Atualmente, os principais parâmetros para predição de malignização em leucoplasias são as características clínicas associadas ...
Flavio Juliano Garcia Santos Pimenta
core  

Mean expression values of the WWOX gene in tumor and normal tissues.

, 2015
a Statistical analyses were performed using the Kruskal-Wallis testMean expression values of the WWOX gene in tumor and normal tissues.
Pelin Bulut (685421), Erkan Kilic (685423), Seda Ekizoglu (685420), Nur Buyru (685424), Emin Karaman (685422)   +4 more
core   +1 more source

Whole‐Exome Sequencing to Screen Personal Neoantigens With High Immunogenicity in Patients With Microsatellite Stability (MSS)–Advanced Colorectal Cancer

Human Mutation, Volume 2026, Issue 1, 2026.
To develop a personalized neoantigen therapy strategy for microsatellite stability (MSS)–advanced colorectal cancer (CRC), neoantigens from collected human CRC samples were screened, and the feasibility and effectiveness of these neoantigens in treating CRC were explored.
Dajiang Li, Wenjing Shen, Siyu Yang, Hongmei Liu, Xiao Tan, Xinrong He, Jingchao Hao, Xinqiang Yin, Finlay Macrae   +8 more
wiley   +1 more source

Comparative mapping and genomic annotation of the bovine oncosuppressor gene WWOX.

, 2009
WWOX (WW domain-containing oxidoreductase) is the gene mapping at FRA16D, HSA16q23.1, the second most active common fragile site in the human genome. In this study we characterized at a detailed molecular level WWOX in the bovine genome.
RUSSO V, BONFIGLIO, SILVIA, ROPERTO F, FERRETTI, LUCA, MALUSA', ARIANNA, Eggen A, Ferretti L., Manera, S., Boussaha M, Malusà A, Denis, Catherine, C., Eggen, Andre,, ROPERTO, FRANCO PEPPINO, Denis, Catherine,, Bonfiglio S, Bonfiglio, S., Perucatti A, Malusà, A., RUSSO, VALERIA, Ferretti, L., Perucatti, A., Di Meo, G.P., Russo, V., Denis C, Di Meo GP, Eggen, Andre, A., Manera S, Roperto, F., Boussaha, Mekki, S. Manera, A. Perucatti, L. Ferretti, M. Boussaha, S. Bonfiglio, C. Denis, A. Eggen, V. Russo, F. Roperto, A. Malusà, G.P. Di Meo   +39 more
core   +2 more sources

WWOX (WW domain containing oxidoreductase) [PDF]

, 2007
Review on WWOX (WW domain containing oxidoreductase), with data on DNA, on the protein encoded, and where the gene is ...
Druck, Teresa, Hagrass, Hoda, Huebner, Kay   +2 more
core  

PARTICLE triplexes cluster in the tumor suppressor WWOX and may extend throughout the human genome

Scientific Reports, 2017
The long non-coding RNA PARTICLE (Gene PARTICL- ‘Promoter of MAT2A-Antisense RadiaTion Induced Circulating LncRNA) partakes in triple helix (triplex) formation, is transiently elevated following low dose irradiation and regulates transcription of its ...
Valerie Bríd O’Leary, Jan Smida, Fabian Andreas Buske, Laura Garcia Carrascosa, Omid Azimzadeh, Doris Maugg, Sarah Hain, Soile Tapio, Wolfgang Heidenreich, James Kerr, Matt Trau, Saak Victor Ovsepian, Michael John Atkinson   +12 more
doaj   +1 more source