Results 81 to 90 of about 89,320 (324)

Possibilities of the use of fast scan voltammetry in simultaneous determination of purines at carbon fiber ultramicroelectrodes

Journal of the Brazilian Chemical Society, 2000
Hypoxanthine, xanthine and uric acid are purines present in extracellular fluids that can be used as metabolic markers, in evaluation of meat conservation and other applications. Voltammetric studies were performed in order to investigate the possibility
Cavalheiro Éder T. G., El-Nour Kholoud A., Brajter-Toth Anna   +2 more
doaj  

Xanthine oxidoreductase: One enzyme for multiple physiological tasks.

Redox Biology, 2021
M. Bortolotti, L. Polito, M. Battelli, A. Bolognesi   +3 more
semanticscholar   +1 more source

N‐ to C‐Glycoside Rearrangement of Uridine 5′‐Phosphate in Two Enzymatic Steps for the Production of Pseudouridine 5′‐Phosphate

Biotechnology and Bioengineering, EarlyView.
The authors present a streamlined cascade reaction for one‐pot N‐C rearrangement of uridine‐5′‐phosphate (UMP) to pseudouridine‐5′‐phosphate (ΨMP; a key mRNA vaccine building block), in two enzymatic steps catalyzed by UMP nucleosidase (EC 3.2.2.10) and ΨMP C‐glycosidase (EC 4.2.1.70).
Martin Pfeiffer, Franziska Guld, Bernd Nidetzky   +2 more
wiley   +1 more source

Participation of reactive oxygen species in regulation of Са2+ - activated К + channels of erythrocytes

Бюллетень сибирской медицины, 2009
In this study, we investigated the effects of preincubation with the reactive oxygen species-generating system xanthine oxidase/xanthine on Ca2+-dependent potassium permeability of erythrocyte membrane. The increase of intracellular calcium concentration
O. A. Trubacheva, S. V. Kremeno, I. V. Petrova, A. V. Sitozhevsky, O. V. Gruzdeva, V. V. Ivanov, T. Ye. Suslova   +6 more
doaj   +1 more source

Mechanistic insights into xanthine oxidoreductase from development studies of candidate drugs to treat hyperuricemia and gout

JBIC Journal of Biological Inorganic Chemistry, 2014
Xanthine oxidoreductase (XOR), which is widely distributed from humans to bacteria, has a key role in purine catabolism, catalyzing two steps of sequential hydroxylation from hypoxanthine to xanthine and from xanthine to urate at its molybdenum cofactor (
T. Nishino, K. Okamoto
semanticscholar   +1 more source

Chemical Characterization of Alphitonia neocaledonica (Schltr.) Guillaumin Bark Extract and Its Anti‐Inflammatory Activities

Chemistry &Biodiversity, EarlyView.
Study of the anti‐inflammatory activities and chemical characterization of Alphitonia neocaledonica (Schltr.) Guillaumin bark extract. ABSTRACT Alphitonia neocaledonica (Schltr.) Guillaumin is a small forest tree endemic of New Caledonia traditionally used to treat rheumatic pain and dermatoses.
Karl Huet, Philippe Georgel, Mohammed Nour, Mohamed Haddad, Edouard Hnawia, Mariko Matsui   +5 more
wiley   +1 more source

Oxidative stress in the pathogenesis of type 1 diabetes: the role of adipocyte xanthine oxidase

Бюллетень сибирской медицины, 2018
Rationale. According to modern understanding, oxidative stress plays an essential role in the underlying mechanisms for the emergence of type 1 and type 2 diabetes and development of complications in these conditions.
V. V. Ivanov, E. V. Shakhristova, E. A. Stepovaya, N. V. Litvjakov, N. A. Perekucha, O. L. Nosareva, T. S. Fedorova, V. V. Novitsky   +7 more
doaj   +1 more source

Differential regulation of hypoxanthine and xanthine by obesity in a general population

Journal of Diabetes Investigation, 2020
Aims/Introduction Uric acid is synthesized by oxidation of hypoxanthine and xanthine using a catalyzing enzyme, xanthine oxidoreductase (XOR), which can be a source of reactive oxygen species.
Masato Furuhashi, Masayuki Koyama, Yukimura Higashiura, Takayo Murase, Takashi Nakamura, Megumi Matsumoto, Akiko Sakai, Hirofumi Ohnishi, Marenao Tanaka, Shigeyuki Saitoh, Norihito Moniwa, Kazuaki Shimamoto, Tetsuji Miura   +12 more
doaj   +1 more source

The Phenolic Content and Bioactivity Assessment of Rubus sanctus Schreber Species with Potential for Food and Ethnopharmacological Uses

Chemistry &Biodiversity, EarlyView.
ABSTRACT In this study, the phytochemical content and various biological activities of Rubus sanctus Schreber species, widely distributed in Turkiye and used in folk medicine, were determined. The ethanol extracts of the root and aerial parts of the species were prepared and their bioactive phytochemical composition was identified by liquid ...
Ismail Yener
wiley   +1 more source

A Review on Xanthine Oxidase-Based Electrochemical Biosensors: Food Safety and Quality Control Applications

Chemosensors
Electrochemical biosensors are integrated bio-receptor–transducer devices that convert specific biological interactions into measurable electrical signals.
Totka Dodevska
doaj   +1 more source