Results 1 to 10 of about 79,386 (326)
Role of urate, xanthine oxidase and the effects of allopurinol in vascular oxidative stress [PDF]
, 2009 Oxidative stress plays an important role in the progression of vascular endothelial dysfunction. The two major systems generating vascular oxidative stress are the NADPH oxidase and the xanthine oxidase pathways. Allopurinol, a xanthine oxidase inhibitor,
George, Jacob, Struthers, Allan D.
core +6 more sources
Screening medicinal plant extracts for xanthine oxidase inhibitory activity
Тонкие химические технологии, 2022 Objectives. The study aimed to test the ethanol extracts of ten medicinal plants for xanthine oxidase inhibitory activity.Methods. The degree of xanthine oxidase inhibitory activity was determined by measuring the absorbance spectrophotometrically at 290
A. C. Ha, Ch. D.P. Nguyen, T. M. Le
doaj +3 more sources
Mechanism of xanthine oxidase in flap ischemia-reperfusion injury and advances in targeted therapy: a mini review [PDF]
Frontiers in PhysiologyIschemia-reperfusion injury in flaps refers to a cascade of pathophysiological reactions that aggravate tissue damage or even cause necrosis. During the period of ischemia followed by restored blood reperfusion, a burst of reactive oxygen species is ...
Weidong Jia, Xin Wei, Xu Gong
doaj +2 more sources
Xanthine Oxidase-A Personal History. [PDF]
Molecules, 2023 A personal perspective is provided regarding the work in several laboratories, including the author’s, that has established the reaction mechanism of xanthine oxidase and related enzymes.
Hille R.
europepmc +6 more sources
Food Chemistry: X, 2022 Pickled radish is a general source of natural bioactive compounds that include phenols. Here, we used molecular docking, fluorescence quenching, circular dichroism spectroscopy and molecular dynamics simulations to identify potential inhibitors against ...
Xiaoze Liu +7 more
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Implication of changes in xanthine oxidase activity following hemodialysis
BMC Nephrology, 2023 Background Xanthine oxidase activity has a key role in the development of oxidative stress and progression of cardiovascular diseases. However, the change of xanthine oxidase activity following hemodialysis and its prognostic impact remain uncertain ...
Hayato Fujioka +5 more
doaj +1 more source
Xanthine oxidase inhibitory activity of Arcangelisia flava
Acta Biochimica Indonesiana, 2022 Background: Hyperuricemia is characterized by elevated levels of uric acid in the blood, produced from its precursor's xanthine and hypoxanthine via xanthine oxidase.
Fatmawati +5 more
doaj +1 more source
Guideline adherence of xanthine oxidase inhibitor utilization to treat gout in primary care [PDF]
J Manag Care Spec PharmClaus L, Auten M, Saseen J, Billups S.
europepmc +3 more sources
Neurobiology of Disease, 2021 Inflammation and oxidative stress contribute to the pathophysiology of diabetic neuropathy. According to recent evidence, the modulation of macrophage polarization in peripheral nerves represents a potential therapeutic target for diabetic neuropathy ...
Kazuhisa Takahashi +9 more
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