Results 1 to 10 of about 78,058 (260)

Screening medicinal plant extracts for xanthine oxidase inhibitory activity

open access: diamondТонкие химические технологии, 2022
Objectives. The study aimed to test the ethanol extracts of ten medicinal plants for xanthine oxidase inhibitory activity.Methods. The degree of xanthine oxidase inhibitory activity was determined by measuring the absorbance spectrophotometrically at 290
A. C. Ha, Ch. D.P. Nguyen, T. M. Le
doaj   +3 more sources

Chemical Comparison and Identification of Xanthine Oxidase Inhibitors of Dioscoreae Hypoglaucae Rhizoma and Dioscoreae Spongiosae Rhizoma by Chemometric Analysis and Spectrum–Effect Relationship [PDF]

open access: goldMolecules, 2023
Dioscoreae hypoglaucae Rhizoma (DH) and Dioscoreae spongiosae Rhizoma (DS) are two similar Chinese herbal medicines derived from the Dioscorea family. DH and DS have been used as medicines in China and other Asian countries for a long time, but study on ...
Guo Rui   +6 more
doaj   +2 more sources

Characterization of xanthine oxidase inhibitory activities of phenols from pickled radish with molecular simulation

open access: yesFood Chemistry: X, 2022
Pickled radish is a general source of natural bioactive compounds that include phenols. Here, we used molecular docking, fluorescence quenching, circular dichroism spectroscopy and molecular dynamics simulations to identify potential inhibitors against ...
Xiaoze Liu   +7 more
doaj   +1 more source

Implication of changes in xanthine oxidase activity following hemodialysis

open access: yesBMC Nephrology, 2023
Background Xanthine oxidase activity has a key role in the development of oxidative stress and progression of cardiovascular diseases. However, the change of xanthine oxidase activity following hemodialysis and its prognostic impact remain uncertain ...
Hayato Fujioka   +5 more
doaj   +1 more source

Xanthine oxidase inhibitory activity of Arcangelisia flava

open access: yesActa Biochimica Indonesiana, 2022
Background: Hyperuricemia is characterized by elevated levels of uric acid in the blood, produced from its precursor's xanthine and hypoxanthine via xanthine oxidase.
Fatmawati   +5 more
doaj   +1 more source

Inhibitory effects of xanthine oxidase inhibitor, topiroxostat, on development of neuropathy in db/db mice

open access: yesNeurobiology of Disease, 2021
Inflammation and oxidative stress contribute to the pathophysiology of diabetic neuropathy. According to recent evidence, the modulation of macrophage polarization in peripheral nerves represents a potential therapeutic target for diabetic neuropathy ...
Kazuhisa Takahashi   +9 more
doaj   +1 more source

Effect of oxidative stress on the activity of human osteoblastic MG63 cells

open access: yes口腔疾病防治, 2017
Objective To investigate the morphology and proliferation viability in oxidative stress induced damage in human MG63 cells. Methods The MG63 cells were treated with superoxide anion (O2.⁃) produced by different con⁃ centrations of xanthine/xanthine ...
WANG Qiong
doaj   +1 more source

Role of urate, xanthine oxidase and the effects of allopurinol in vascular oxidative stress [PDF]

open access: yes, 2009
Oxidative stress plays an important role in the progression of vascular endothelial dysfunction. The two major systems generating vascular oxidative stress are the NADPH oxidase and the xanthine oxidase pathways. Allopurinol, a xanthine oxidase inhibitor,
George, Jacob, Struthers, Allan D.
core   +4 more sources

Determination of serum adenosine deaminase and xanthine oxidase levels in patients with crimean-congo hemorrhagic fever

open access: yesClinics, 2010
OBJECTIVE: Crimean-Congo hemorrhagic fever is an acute viral hemorrhagic fever with a high mortality rate. Despite increasing knowledge about hemorrhagic fever viruses, little is known about the pathogenesis of Crimean-Congo hemorrhagic fever.
V. Kenan Celik   +5 more
doaj   +1 more source

Xanthine oxidase inhibitors are associated with reduced risk of cardiovascular disease

open access: yesScientific Reports, 2021
As previous studies have reported finding an association between hyperuricemia and the development of cardiovascular and chronic kidney disease, hyperuricemia is thought to be an independent risk factor for hypertension and diabetic mellitus. However, we
Hirotaka Saito   +10 more
doaj   +1 more source

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