Results 111 to 120 of about 78,058 (260)

Insights on Regioselective Synthesis of Fused Thiazoles: Density Functional Theory Calculations, Local Reactivity Indices, and Molecular Electrostatic Potential Analysis

ChemistryOpen, EarlyView.
A regioselective synthesis of fused thiazoles was achieved via aza‐Michael cyclization of thiazolidinone derivatives with hydrazines or heteroaryl amines. Density functional theory, local reactivity indices, and molecular electrostatic potential mapping are used to explain selectivity.
Ghaferah H. Al‐Hazmi, Jehan Y. Al‐Humaidi, Sayed M. Riyadh, Mohamed S. M. Ahmed, Magdi E. A. Zaki, Awatif H. Alruwaili, Khaled A. Alanazi, Rajeh H. Almutairi, Sobhi M. Gomha   +8 more
wiley   +1 more source

Effect of ELF e.m. fields on metalloprotein redox-active sites

, 2007
The peculiarity of the distribution and geometry of metallic ions in enzymes pushed us to set the hypothesis that metallic ions in active-site act like tiny antennas able to pick up very feeble e.m. signals.
Badon, T., Barbaro, F., Bernardini, D., De Ninno, A., Ferrari, V., Gerardi, G., Prosdocimi, M.   +6 more
core  

The chemistry of xanthine oxidase. 9. An improved method of preparing the bovine milk enzyme [PDF]

, 1964
DA Gilbert, F. Bergel
openalex   +1 more source

Brain‐Targeted Multifunctional Liposomes Reprogram Microglia via Anti‐Inflammatory Signaling and Reactive Oxygen Species Scavenging to Treat Post‐Traumatic Neuroinflammation

Small Structures, EarlyView.
Excessive inflammatory microglial cells in traumatic brain injury (TBI) site is a major driver of postinjury chronic neuroinflammation. A nanointegrative strategy is reported that enables efficient remodeling of TBI‐residing microglial cell fate specification through cooperative inhibition of NF‐κB/MAPK/TLR4 signaling and reactive oxygen species ...
Xuan Wang, Zhiqi Hu, Youbo Zhao, Yang Fei, Menghuan Li, Min Su, Zhong Luo, Rong Hu   +7 more
wiley   +1 more source

Global Fluoride Toxicology Landscape: Bibliometric Approaches and Scientific Mapping

Environmental Toxicology, EarlyView.
ABSTRACT This study analyzed research trends in the 100 most‐cited articles on fluoride toxicology, a topic widely debated due to the toxic effects associated with levels deemed safe for human exposure. A bibliometric analysis was conducted using the Web of Science‐Core Collection, extracting data such as citation count, authors, keywords, journal ...
Maria Karolina Martins Ferreira, Deiweson Souza‐Monteiro, Priscila Cunha Nascimento, Luciana Eiró‐Quirino, Leonardo Oliveira Bittencourt, Fatemeh Vida Zohoori, Esperanza Angeles Martinez‐Mier, Marilia Afonso Rabelo Buzalaf, Rafael Rodrigues Lima   +8 more
wiley   +1 more source

Parang Romang (Boehmeria virgata (Frost.) Guill.): Correlation of Phytochemistry with Antioxidant and Xanthine Oxidase Inhibitory Activities

Hayati Journal of Biosciences
Secondary metabolites such as phenolic and flavonoid from the plant are essential in their activity, especially activities related to the prevention of oxidation and the inhibition of xanthine oxidase.
Muhammad Ikhlas Arsul, Irda Fidrianny, Muhamad Insanu   +2 more
doaj   +1 more source

Renal denervation attenuates hypertension and renal dysfunction in a model of cardiovascular and renal disease, which is associated with reduced NADPH and xanthine oxidase activity

Redox Biology, 2017
Oxidative stress is considered a central pathophysiological event in cardiovascular disease, including hypertension. Early age reduction in renal mass is associated with hypertension and oxidative stress in later life, which is aggravated by increased ...
Maria Peleli, Peter Flacker, Zhengbing Zhuge, Cristina Gomez, Craig E. Wheelock, A. Erik G. Persson, Mattias Carlstrom   +6 more
doaj   +1 more source

The molybdenum centre of native xanthine oxidase. Evidence for proton transfer from substrates to the centre and for existence of an anion-binding site [PDF]

, 1978
Steven Gutteridge, Stephen Tanner, Robert C. Bray   +2 more
openalex   +1 more source

Recent developments in the chemistry and enzyme inhibitory activity of fused thiazoles and thiadiazoles

Vietnam Journal of Chemistry, EarlyView.
Abstract The combination of cyclization reactions of thiadiazoles and benzothiazoles with Pd‐catalyzed cross‐coupling reactions provided a convenient synthesis of annulated, fluorinated and non‐fluorinated heterocycles, such as 1,3,4‐thiadiazolo[3,2‐a]pyrimidin‐5‐ones, benzothiazolo[3,2‐a]pyridimidin‐4‐ones, benzothiazolo[2,3‐b]quinazolin‐12‐ones and ...
Peter Langer
wiley   +1 more source

Amino Acid Patterns that Determine Antihyperuricemic Activity of Peptides: Identification and Predictive Analysis

Техника и технология пищевых производств
Peptides offer a promising analogue to synthetic drugs in treating hyperuricemia. This article introduces reliable amino acid patterns that cause the inhibitory xanthine oxidase (CSR) activity of peptides.
Anastasia V. Smirnova, Sergey L. Tikhonov   +1 more
doaj   +1 more source