Results 111 to 120 of about 79,386 (326)

The Sooner, the Better: Neuroprotective Strategies in Fetuses With Congenital Heart Disease

Prenatal Diagnosis, EarlyView.
ABSTRACT Congenital heart disease (CHD) is the most frequent congenital malformation at birth and is associated with neurodevelopmental impairments. Alterations in cardiovascular physiology can lead to reduced cerebral blood perfusion and oxygenation, which negatively affects brain growth and maturation.
Maaike Nijman, Mirthe E. M. van der Meijden, Johannes M. P. J. Breur, Raymond Stegeman, Nicolaas J. G. Jansen, Mireille N. Bekker, Manon J. N. L. Benders, Nathalie H. P. Claessens   +7 more
wiley   +1 more source

Increased Adenine Nucleotide Degradation in Skeletal Muscle Atrophy [PDF]

, 2019
Adenine nucleotides (AdNs: ATP, ADP, AMP) are essential biological compounds that facilitate many necessary cellular processes by providing chemical energy, mediating intracellular signaling, and regulating protein metabolism and solubilization.
Brault, Jeffrey J., Hafen, Paul S., Miller, Spencer G.   +2 more
core   +1 more source

Hydrogel Microneedle Array‐Based Transdermal Dressing System for Multiplexed Assessment and Intelligent Therapy of Chronic Wounds

Small, EarlyView.
This work develops a theranostic wound microneedle dressing integrates a therapeutic MXene‐infused hydrogel with a high‐conductive sensor array enabled by a novel laser‐scribing technique. The platform actively promotes wound healing and provides antibacterial action while continuously monitoring seven key biomarkers.
Md Sharifuzzaman, Gauri Hasabnis, Sheikh Ahmed Abu Saleh, Leonard Siebert, Jan‐Bernd Hövener, Gregor Maschkowitz, Zeynep Altintas   +6 more
wiley   +1 more source

Gas chromatographic-mass spectrometric (GC-MS) analysis and virtual screening of ripped fruit of Dialium guineense for potential inhibitors of integrase, cycloxygenase-1, and xanthine oxidase [PDF]

, 2022
Patrick Maduabuchi Aja, Peter Chinedu Agu, Boniface Anthony Ale, J.N. Awoke, Hilary Akobi Ogwoni, Muhammad Akram, E. U. Ekpono, I. O. Igwenyi, Patience N. Ogbu, Okechukwu Paul-Chima Ugwu, Josiah Esoghene Ifie, Sandra Ifie Etumah, Emmanuel Adegboyega Aboyomi, Muhammad Daniyal, Emmanuel Maduabuchi Ezeh, Onyedika Gabriel Ani   +15 more
openalex   +1 more source

Nanomaterial‐Based Inkjet Printing for Electrochemical Sensing

Small, EarlyView.
Inkjet printing provides a digitally controlled, versatile, and highly reproducible method for fabricating and functionalizing sensing devices. This Perspective highlights how homogeneous, material‐efficient deposition enables precise patterning of functional inks and scalable integration of sensors for chemical and biological detection. The discussion
David Panáček, Massimo Urban, Alessandro Silvestri, Ivan Dědek, Martin‐Alex Nalepa, Arben Merkoçi, Maurizio Prato, Michal Otyepka   +7 more
wiley   +1 more source

Superoxide Radical Dismutation as New Therapeutic Strategy in Parkinson’s Disease [PDF]

, 2017
open4siAging is the biggest risk factor for developing many neurodegenerative disorders, including idiopathic Parkinson's disease (PD). PD is still an incurable disorder and the available medications are mainly directed to the treatment of symptoms in ...

core   +1 more source

Global Fluoride Toxicology Landscape: Bibliometric Approaches and Scientific Mapping

Environmental Toxicology, EarlyView.
ABSTRACT This study analyzed research trends in the 100 most‐cited articles on fluoride toxicology, a topic widely debated due to the toxic effects associated with levels deemed safe for human exposure. A bibliometric analysis was conducted using the Web of Science‐Core Collection, extracting data such as citation count, authors, keywords, journal ...
Maria Karolina Martins Ferreira, Deiweson Souza‐Monteiro, Priscila Cunha Nascimento, Luciana Eiró‐Quirino, Leonardo Oliveira Bittencourt, Fatemeh Vida Zohoori, Esperanza Angeles Martinez‐Mier, Marilia Afonso Rabelo Buzalaf, Rafael Rodrigues Lima   +8 more
wiley   +1 more source

Potential role of NADPH-oxidase in early steps of lead-induced oxidative burst in Vicia faba roots [PDF]

, 2008
The mechanism of oxidative burst induced by lead in Vicia faba excised roots was investigated by luminol-dependent chemiluminescence. Results showed that lead triggered a rapid and dose-dependent increase in chemiluminescence production.
Cecchi, Marie, Guiresse, Agnès Maritchù, Perchet, Geoffrey-Thibault, Pinelli, Eric, Pourrut, Bertrand, Silvestre, Jérôme   +5 more
core   +3 more sources

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Update on diagnosis, nonpharmacological treatment and prevention of Equine Gastric Ulcer Syndrome (EGUS)

Equine Veterinary Education, EarlyView.
Summary The term Equine Gastric Ulcer Syndrome (EGUS) has been used since 1999. As there are important differences, the terms Equine Squamous Gastric Disease (ESGD) and Equine Glandular Gastric Disease (EGGD) were introduced in 2015. Risk factors like dietary management, training regimens and drug side effects, as described for NSAIDs, predispose ...
R. Lensing, A. K. Barton
wiley   +1 more source