Results 11 to 20 of about 78,058 (260)

Association of Xanthine Oxidase and Neutrophil Activation Marker Elastase in Preeclampsia: A Case-control Study [PDF]

open access: goldJournal of Clinical and Diagnostic Research, 2021
Introduction: Preeclampsia is an obstetric emergency for both mother and the foetus with unknown aetiology. Delivery is the only effective way in the prompt management.
Ramya Rajshekar   +4 more
doaj   +2 more sources

Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase-catalyzed xanthine and 6-mercaptopurine oxidation. [PDF]

open access: yesJ Sci Food Agric
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Bencsik T   +6 more
europepmc   +2 more sources

Gout [PDF]

open access: yes, 2008
INTRODUCTION: Gout affects about 5% of men and 1% of women, with up to 80% of people experiencing a recurrent attack within 3 years. METHODS AND OUTCOMES:We conducted a systematic review and aimed to answer the following clinical questions: What are the
Underwood, Martin
core   +3 more sources

Oxidative stress in the pathogenesis of type 1 diabetes: the role of adipocyte xanthine oxidase

open access: yesБюллетень сибирской медицины, 2018
Rationale. According to modern understanding, oxidative stress plays an essential role in the underlying mechanisms for the emergence of type 1 and type 2 diabetes and development of complications in these conditions.
V. V. Ivanov   +7 more
doaj   +1 more source

Comparison of Xanthine Oxidase Inhibitory Effect of Swertia chirayita and Febuxostat in Vitro

open access: yesProceedings, 2021
Introduction:Plasma uric acid ? 6.5 to 7.0 mg/dl increases the incidence of gout, hypertension, diabetes mellitus type 2, stroke and heart failure. Low purine diet, use of xanthine oxidase inhibitors allopurinol and febuxostat; or uricosuric agent’s ...
Qura-Tul-Ain   +5 more
doaj   +1 more source

The role of urate and xanthine oxidase in vascular oxidative stress:Future directions [PDF]

open access: yes, 2009
Vascular oxidative stress has been shown to be a potent factor in the pathophysiology of endothelial dysfunction. Despite current optimal evidence-based therapy, mortality from various cardiovascular disorders remains high.
George, Jacob, Struthers, Allan
core   +5 more sources

Biochemistry Changes That Occur after Death: Potential Markers for Determining Post-Mortem Interval [PDF]

open access: yes, 2013
Death is likely to result in very extensive biochemical changes in all body tissues due to lack of circulating oxygen, altered enzymatic reactions, cellular degradation, and cessation of anabolic production of metabolites.
Donaldson, Andrea
core   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

open access: yesHepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan   +19 more
wiley   +1 more source

Quantification of Uric Acid or Xanthine in Plant Samples

open access: yesBio-Protocol, 2015
We developed this protocol to assay and quantify the content of uric acid or xanthine in various tissues of Arabidopsis thaliana mutant lines with defective urate oxidase or xanthine dehydrogenase1 and in their complementation and suppressor lines (Hauck
Oliver Hauck, Claus-Peter Witte
doaj   +1 more source

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