Association of Xanthine Oxidase and Neutrophil Activation Marker Elastase in Preeclampsia: A Case-control Study [PDF]
Introduction: Preeclampsia is an obstetric emergency for both mother and the foetus with unknown aetiology. Delivery is the only effective way in the prompt management.
Ramya Rajshekar +4 more
doaj +2 more sources
Influence of xanthine oxidase inhibitors on all-cause mortality in adults: a systematic review and meta-analysis. [PDF]
Nowak MM +3 more
europepmc +3 more sources
Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase-catalyzed xanthine and 6-mercaptopurine oxidation. [PDF]
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Bencsik T +6 more
europepmc +2 more sources
INTRODUCTION: Gout affects about 5% of men and 1% of women, with up to 80% of people experiencing a recurrent attack within 3 years. METHODS AND OUTCOMES:We conducted a systematic review and aimed to answer the following clinical questions: What are the
Underwood, Martin
core +3 more sources
Oxidative stress in the pathogenesis of type 1 diabetes: the role of adipocyte xanthine oxidase
Rationale. According to modern understanding, oxidative stress plays an essential role in the underlying mechanisms for the emergence of type 1 and type 2 diabetes and development of complications in these conditions.
V. V. Ivanov +7 more
doaj +1 more source
Comparison of Xanthine Oxidase Inhibitory Effect of Swertia chirayita and Febuxostat in Vitro
Introduction:Plasma uric acid ? 6.5 to 7.0 mg/dl increases the incidence of gout, hypertension, diabetes mellitus type 2, stroke and heart failure. Low purine diet, use of xanthine oxidase inhibitors allopurinol and febuxostat; or uricosuric agent’s ...
Qura-Tul-Ain +5 more
doaj +1 more source
The role of urate and xanthine oxidase in vascular oxidative stress:Future directions [PDF]
Vascular oxidative stress has been shown to be a potent factor in the pathophysiology of endothelial dysfunction. Despite current optimal evidence-based therapy, mortality from various cardiovascular disorders remains high.
George, Jacob, Struthers, Allan
core +5 more sources
Biochemistry Changes That Occur after Death: Potential Markers for Determining Post-Mortem Interval [PDF]
Death is likely to result in very extensive biochemical changes in all body tissues due to lack of circulating oxygen, altered enzymatic reactions, cellular degradation, and cessation of anabolic production of metabolites.
Donaldson, Andrea
core +1 more source
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan +19 more
wiley +1 more source
Quantification of Uric Acid or Xanthine in Plant Samples
We developed this protocol to assay and quantify the content of uric acid or xanthine in various tissues of Arabidopsis thaliana mutant lines with defective urate oxidase or xanthine dehydrogenase1 and in their complementation and suppressor lines (Hauck
Oliver Hauck, Claus-Peter Witte
doaj +1 more source

