Results 41 to 50 of about 79,386 (326)

Alcool e radicais livres de oxigénio.

Acta Médica Portuguesa, 1993
Oxygen free radicals may be generated during ethanol metabolization by cytochrome P450, or due to the formation of xanthine oxidase by ethanol effect on xanthine dehydrogenase.
M L Mira, C F Manso
doaj   +1 more source

Literature-based discovery of diabetes- and ROS-related targets [PDF]

, 2010
Background Reactive oxygen species (ROS) are known mediators of cellular damage in multiple diseases including diabetic complications. Despite its importance, no comprehensive database is currently available for the genes associated with ROS.
A Erol, A Fontayne, A Iaccio, Adam D Schuyler, AG Reaume, AM Vincent, AM Vincent, AM Vincent, AM Vincent, American-Diabetes-Association, BJ Turner, C Figueroa-Romero, C Plake, D Rebholz-Schuhmann, David J States, E Schwedhelm, EH Sarsour, EL Feldman, EM Olofsson, Eva L Feldman, F Folli, FA Hakim, FR DeRubertis, H Ilieva, H V Jagadish, HB Lee, I Vastrik, J Hur, JL Edwards, JM Jimenez-Andrade, JS Pan, Junguk Hur, JW Russell, KA Sullivan, Kelli A Sullivan, KK Ohlemiller, L Hirschman, M Ashburner, M Brownlee, M Fukuda, M Fukuda, M Kanehisa, M Kawase, Manjusha Pande, N Kameyama, PJ Shaw, RA Fisher, S Cetinkalp, S Ghosh, T Matsunami, VI Perez, Y Aliciguzel, Y Benjamini, Yu Hong, Z Bagi   +54 more
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Uji Penghambatan Xantin Oksidase Secara In Vitro Ekstrak Kulit Rambutan

Pharmaceutical Sciences and Research, 2016
Hyperuricemia is a condition that uric acid levels increased and cause accumulated uric acid crystals in the tissues. Xanthine oxidase is an enzyme which catalyze the oxidation of hypoxanthine into xanthine and into uric acid.
Nurul Eka Putri, Rissyelly, Marista Gilang Mauldina   +2 more
doaj   +1 more source

Lipid peroxidation is a nonparenchymal cell event with reperfusion after prolonged liver ischemia [PDF]

, 1990
A proposed mechanism for irreversible ischemic liver damage has been peroxidation of membrane phospholipids by free radicals. However, the hepatocyte is laden with enzymes which are antioxidants and, therefore, ought to be relatively resistant to ...
Makowka, L, Rao, PN, Starzl, TE, Walsh, TR   +3 more
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Chemical Evidence for Potent Xanthine Oxidase Inhibitory Activity of Ethyl Acetate Extract of Citrus aurantium L. Dried Immature Fruits

Molecules, 2016
Xanthine oxidase is a key enzyme which can catalyze hypoxanthine and xanthine to uric acid causing hyperuricemia in humans. Xanthine oxidase inhibitory activities of 24 organic extracts of four species belonging to Citrus genus of the family Rutaceae ...
Kun Liu, Wei Wang, Bing-Hua Guo, Hua Gao, Yang Liu, Xiao-Hong Liu, Hui-Li Yao, Kun Cheng   +7 more
doaj   +1 more source

7-Keto-Cholesterol and Cholestan-3beta, 5alpha, 6beta-Triol Induce Eryptosis through Distinct Pathways Leading to NADPH Oxidase and Nitric Oxide Synthase Activation [PDF]

, 2019
BACKGROUND/AIMS: We showed that patho-physiological concentrations of either 7-keto-cholesterol (7-KC), or cholestane-3beta, 5alpha, 6beta-triol (TRIOL) caused the eryptotic death of human red blood cells (RBC), strictly dependent on the early production
Allegra M., Attanzio A., Cilla A., Frazzitta A., Livrea M. A., Tesoriere L.   +5 more
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In vitro investigation of xanthine oxidase inhibitory and antioxidant activities of 3,4,5-trihydroxycinnamic acid [PDF]

Journal of HerbMed Pharmacology
Introduction: Xanthine oxidase inhibitors with strong antioxidant activity are promising candidates for the treatment of gout and reactive oxygen species (ROS)-related disorders.
Taweesak Dhammaraj, Phoobet Kotseekieo, Tunnathon Chotikarn, Narumol Phosrithong, Wattanakarn Praison, Tossapol Prasomsub, Panupong Lumthong, Warangrat Supaporn, Bunleu Sungthong, Chawannuch Mudjupa, Pawitra Pulbutr   +10 more
doaj   +1 more source

Effect of ischemia on the canine large bowel: A comparison with the small intestine [PDF]

, 1996
Mucosal injury caused by ischemia and reperfusion has been well documented with the small intestine, but little is known about the colon. In the present study, the effect of warm and cold ischemia on the canine colon was studied and compared to that on ...
Ikoma, A, Nakamura, K, Starzl, TE, Takeyoshi, I, Todo, S, Zhang, S, Zhu, Y   +6 more
core   +1 more source

The mechanism and significance of the conversion of xanthine dehydrogenase to xanthine oxidase in mammalian secretory gland cells

Redox Biology, 2023
The conversion of xanthine dehydrogenase (XDH) to xanthine oxidase (XO) occurs only in mammalian species. In fresh bovine milk, the enzyme exists predominantly as the oxidase form, in contrast to various normal organs where it is found primarily as the ...
Teruo Kusano, Tomoko Nishino, Ken Okamoto, Russ Hille, Takeshi Nishino   +4 more
doaj   +1 more source

Effects of industrial heat treatments on the kinetics of inactivation of antimicrobial bovine milk xanthine oxidase. [PDF]

, 2019
Milk is a source of antimicrobial systems such as xanthine oxidoreductase, which has been proposed to modulate the oral and gut microbiota of infants.
de Moura Bell, Juliana MLN, German, J Bruce, Ozturk, Gulustan   +2 more
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