RSC Advances, 2019 The molecular property–affinity relationships of dietary flavonoids binding to xanthine oxidase were investigated in vitro by comparing the binding constants obtained from a fluorescence-quenching method. The inhibitions of dietary flavonoids on xanthine
Mengmeng Yuan +6 more
semanticscholar +1 more source
Optimization of extraction conditions of phytochemical compounds and anti-gout activity of euphorbia hirta l. (Ara Tanah) using response surface methodology and Liquid Chromatography-Mass Spectrometry (LC-MS) analysis [PDF]
, 2019 Gout is a common disease affected most of the people due to the elevation of uric acid in the blood. Flavonoid and phenolic compounds are reported to exert the anti-gout activity of medicinal plants. Hence, this study aimed at optimizing the extraction
Abdullah, Norazlin +4 more
core +1 more source
Reduction of leukocyte microvascular adherence and preservation of blood-brain barrier function by superoxide-lowering therapies in a piglet model of neonatal asphyxia [PDF]
, 2019 Background: Asphyxia is the most common cause of brain damage in newborns. Substantial evidence indicates that leukocyte recruitment in the cerebral vasculature during asphyxia contributes to this damage. We tested the hypothesis that superoxide radical (
Aarti R. Shah +9 more
core +2 more sources
Shipin gongye ke-ji, 2023 Objective: To optimize the extraction process of Ilex latifolia Thunb. polysaccharide and analyze its inhibitory activity of xanthine oxidase. Methods: A response surface optimization ultrasound-assisted method was used to study the effects of material ...
Zhongying LU, Mengqin ZHANG, Xiang CHEN
doaj +1 more source
Biochemistry Changes That Occur after Death: Potential Markers for Determining Post-Mortem Interval [PDF]
, 2013 Death is likely to result in very extensive biochemical changes in all body tissues due to lack of circulating oxygen, altered enzymatic reactions, cellular degradation, and cessation of anabolic production of metabolites.
Donaldson, Andrea
core +1 more source
Quantification of Uric Acid or Xanthine in Plant Samples
Bio-Protocol, 2015 We developed this protocol to assay and quantify the content of uric acid or xanthine in various tissues of Arabidopsis thaliana mutant lines with defective urate oxidase or xanthine dehydrogenase1 and in their complementation and suppressor lines (Hauck
Oliver Hauck, Claus-Peter Witte
doaj +1 more source
CAQ Corner: Basic concepts of transplant immunology
, 2022 Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
Pharmacology and clinical drug candidates in redox medicine [PDF]
, 2015 SIGNIFICANCE Oxidative stress is suggested to be a disease mechanism common to a wide range of disorders affecting human health. However, so far, the pharmacotherapeutic exploitation of this, for example, based on chemical scavenging of pro-oxidant ...
Casas, Ana I +11 more
core +2 more sources
Exercise Training Ameliorates Renal Oxidative Stress in Rats with Chronic Renal Failure
Metabolites, 2022 In patients with chronic kidney disease, exercise training with moderate intensity protects renal function and improves mortality. However, the mechanisms of the renal protective effects of exercise training in chronic kidney disease have not been ...
Seiko Yamakoshi +4 more
doaj +1 more source
Crucial involvement of xanthine oxidase in the intracellular signalling networks associated with human myeloid cell function [PDF]
, 2014 Xanthine oxidase (XOD) is an enzyme which plays a central role in purine catabolism by converting hypoxanthine into xanthine and then further into uric acid.
Abooali, Maryam +5 more
core +1 more source