The species distribution of xanthine oxidase [PDF]
Biochemical Journal, 1965 1. The distribution of xanthine oxidase in blood and tissues of various animals was studied by means of a radioactive assay capable of detecting 10(-7) unit of enzyme. The method was shown to be applicable to tissues with a high uricase content. 2. Of 16 mammalian species examined, six had low concentrations of xanthine oxidase in the serum. In six non-
T. H. Chaglassian, U. A. S. Al-Khalidi
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Novel perspectives in redox biology and pathophysiology of failing myocytes: modulation of the intramyocardial redox milieu for therapeutic interventions - A review article from the Working Group of Cardiac Cell Biology, Italian Society of Cardiology [PDF]
, 2016 The prevalence of heart failure (HF) is still increasing worldwide, with enormous human, social, and economic costs, in spite of huge efforts in understanding pathogeneticmechanisms and in developing effective therapies that have transformed this ...
Angelini, Annalisa +8 more
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Бюллетень сибирской медицины, 2009 In this study, we investigated the effects of preincubation with the reactive oxygen species-generating system xanthine oxidase/xanthine on Ca2+-dependent potassium permeability of erythrocyte membrane. The increase of intracellular calcium concentration
O. A. Trubacheva +6 more
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Optimization of extraction conditions of phytochemical compounds and anti-gout activity of euphorbia hirta l. (Ara Tanah) using response surface methodology and Liquid Chromatography-Mass Spectrometry (LC-MS) analysis [PDF]
, 2019 Gout is a common disease affected most of the people due to the elevation of uric acid in the blood. Flavonoid and phenolic compounds are reported to exert the anti-gout activity of medicinal plants. Hence, this study aimed at optimizing the extraction
Abdullah, Norazlin +4 more
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Screening of methanol extracts of sixty plants from Kerman for their potential xanthine oxidase inhibitory activity [PDF]
Journal of HerbMed Pharmacology, 2017 Introduction: Gout is a chronic metabolic disease in which xanthine oxidase plays a crucial role. Many natural compounds such as various flavonoids have been reported to have inhibitory effect on xanthine oxidase.
Ahmad Gholamhoseinian +2 more
doaj
Alcool e radicais livres de oxigénio.
Acta Médica Portuguesa, 1993 Oxygen free radicals may be generated during ethanol metabolization by cytochrome P450, or due to the formation of xanthine oxidase by ethanol effect on xanthine dehydrogenase.
M L Mira, C F Manso
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Biology, 2023 Hyperuricemia, an abnormally high level of blood uric acid, is a major risk factor for gout. Although xanthine oxidase inhibitors were clinically used to lower blood uric acid level, the concerned side effects restricted their utilization. In this study,
Kuo-Ching Huang +8 more
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Pharmacology and clinical drug candidates in redox medicine [PDF]
, 2015 SIGNIFICANCE Oxidative stress is suggested to be a disease mechanism common to a wide range of disorders affecting human health. However, so far, the pharmacotherapeutic exploitation of this, for example, based on chemical scavenging of pro-oxidant ...
Casas, Ana I +11 more
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, 2017 The present study aims to improve the biological activities of luteolin by complexation with manganese(II). UV-visible spectroscopy, infrared spectroscopy, thermogravimetric analysis and elemental analysis were adopted to assess the relevant interaction ...
Hao Dong +5 more
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Uji Penghambatan Xantin Oksidase Secara In Vitro Ekstrak Kulit Rambutan
Pharmaceutical Sciences and Research, 2016 Hyperuricemia is a condition that uric acid levels increased and cause accumulated uric acid crystals in the tissues. Xanthine oxidase is an enzyme which catalyze the oxidation of hypoxanthine into xanthine and into uric acid.
Nurul Eka Putri +2 more
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