Results 71 to 80 of about 299,059 (319)

Effects of industrial heat treatments on the kinetics of inactivation of antimicrobial bovine milk xanthine oxidase. [PDF]

open access: yes, 2019
Milk is a source of antimicrobial systems such as xanthine oxidoreductase, which has been proposed to modulate the oral and gut microbiota of infants.
de Moura Bell, Juliana MLN   +2 more
core  

Seizure activity results in calcium- and mitochondria-independent ROS production via NADPH and xanthine oxidase activation

open access: yesCell Death and Disease, 2014
Seizure activity has been proposed to result in the generation of reactive oxygen species (ROS), which then contribute to seizure-induced neuronal damage and eventually cell death.
S. Kovac   +4 more
semanticscholar   +1 more source

Communications Among Neurocytes in Parkinson's Disease Regulated by Differential Metabolism and Blood‐Brain Barrier Traversing of Chiral Gold Cluster‐MOF Integrated Nanoparticles

open access: yesAdvanced Science, EarlyView.
This study have loaded chiral gold nanoclusters onto the inner and outer surfaces of ZIF and uncovers the biodistribution, metabolic variances, and therapeutic mechanism of chiral nanoparticles, providing deep insights into the nanobiological effects of chiral anti‐inflammatory nanomedicines in PD therapy for future clinical transformation.
Junyang Chen   +7 more
wiley   +1 more source

PENGHAMBATAN AKTIVITAS XANTHINE OXIDASE OLEH EKSTRAK ETANOL SARANG SEMUT (Myrmecodia tuberosa (non Jack) Bl.) SECARA IN VITRO

open access: yesPharmaciana, 2014
Uric acid is the end product of purine metabolism that can settle in the joints and form small crystals, causing inflammation known as gout. Gout is a disease caused by high levels of uric acid in the blood (hyperuricemia).
Ernawati Ernawati, Hari Susanti
doaj   +1 more source

Xanthine Oxidase Inhibitory Activity and Chemical Composition of Pistacia chinensis Leaf Essential Oil

open access: yesPharmaceutics, 2022
Gout is a common metabolic disease caused by abnormal purine metabolism that promotes the formation and deposition of monosodium urate crystals within joints that causes acute arthritis and can seriously affect the daily life of patients.
Chi-Ya Huang   +3 more
doaj   +1 more source

The Iron‐Sulfur Cluster of Bacterioferritin‐Associated Ferredoxin (Bfd): A ‘Biological Fuse’ that Prevents Oxidative Damage to Cells?

open access: yesAngewandte Chemie International Edition, Accepted Article.
Iron is in an essential micronutrient in living systems. However, it is also potentially toxic and so the concentration of chelatable iron within cells is tightly regulated to prevent catalytic formation of harmful reactive oxygen species (ROS). Ferritins play a key role in iron homeostasis by storing excess iron as an insoluble ferric mineral within ...
Justin M. Bradley   +4 more
wiley   +1 more source

In silico design and synthesis of hesperitin derivatives as new xanthine oxidase inhibitors

open access: yesBMC Chemistry, 2019
Background Hesperitin, a naturally occurring flavonoid was hybridized with phenolic acids to evaluate its potential to inhibit the activity of xanthine oxidase (XO), a key enzyme which catalyses xanthine to uric acid which is found to be associated with ...
Neelam Malik   +2 more
doaj   +1 more source

Anthocyanin Identification of Methanol-HCl Extract Active Fraction in Rosella (Hibiscus Sabdariffa. L) and Its Potential as Xanthine Oxidase Inhibitor [PDF]

open access: yes, 2014
The active fraction of methanol-HCl extract of Roselle flower (Hibiscus sabdariffa. L) has been identified and its inhibitor xanthine oxidase potential tested. The aim of this study was to compare the inhibitory activity of xanthine oxidase from methanol-
Anam, K. (Khairul)   +2 more
core  

Xanthine oxidase/hydrogen peroxide generates sulfur trioxide anion radical (SO.−3) from sulfite (SO2−3) [PDF]

open access: yes
In the presence of hydrogen peroxide (H2O2), xanthine oxidase has been found to catalyze sulfur trioxide anion radical (SO.−3) formation from sulfite anion (SO2−3).
Dalal, N.S., Shi, Xianglin, Sun, Xiaoya
core   +1 more source

Allopurinol use yields potentially beneficial effects on inflammatory indices in those with recent ischemic stroke: a randomized, double-blind, placebo-controlled trial [PDF]

open access: yes, 2008
<p><b>Background and Purpose</b>: Elevated serum uric acid level is associated with poor outcome and increased risk of recurrent events after stroke.
Dawson, J.   +6 more
core   +1 more source

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