Results 71 to 80 of about 299,059 (319)
Effects of industrial heat treatments on the kinetics of inactivation of antimicrobial bovine milk xanthine oxidase. [PDF]
Milk is a source of antimicrobial systems such as xanthine oxidoreductase, which has been proposed to modulate the oral and gut microbiota of infants.
de Moura Bell, Juliana MLN+2 more
core
Seizure activity has been proposed to result in the generation of reactive oxygen species (ROS), which then contribute to seizure-induced neuronal damage and eventually cell death.
S. Kovac+4 more
semanticscholar +1 more source
This study have loaded chiral gold nanoclusters onto the inner and outer surfaces of ZIF and uncovers the biodistribution, metabolic variances, and therapeutic mechanism of chiral nanoparticles, providing deep insights into the nanobiological effects of chiral anti‐inflammatory nanomedicines in PD therapy for future clinical transformation.
Junyang Chen+7 more
wiley +1 more source
Uric acid is the end product of purine metabolism that can settle in the joints and form small crystals, causing inflammation known as gout. Gout is a disease caused by high levels of uric acid in the blood (hyperuricemia).
Ernawati Ernawati, Hari Susanti
doaj +1 more source
Gout is a common metabolic disease caused by abnormal purine metabolism that promotes the formation and deposition of monosodium urate crystals within joints that causes acute arthritis and can seriously affect the daily life of patients.
Chi-Ya Huang+3 more
doaj +1 more source
Iron is in an essential micronutrient in living systems. However, it is also potentially toxic and so the concentration of chelatable iron within cells is tightly regulated to prevent catalytic formation of harmful reactive oxygen species (ROS). Ferritins play a key role in iron homeostasis by storing excess iron as an insoluble ferric mineral within ...
Justin M. Bradley+4 more
wiley +1 more source
In silico design and synthesis of hesperitin derivatives as new xanthine oxidase inhibitors
Background Hesperitin, a naturally occurring flavonoid was hybridized with phenolic acids to evaluate its potential to inhibit the activity of xanthine oxidase (XO), a key enzyme which catalyses xanthine to uric acid which is found to be associated with ...
Neelam Malik+2 more
doaj +1 more source
Anthocyanin Identification of Methanol-HCl Extract Active Fraction in Rosella (Hibiscus Sabdariffa. L) and Its Potential as Xanthine Oxidase Inhibitor [PDF]
The active fraction of methanol-HCl extract of Roselle flower (Hibiscus sabdariffa. L) has been identified and its inhibitor xanthine oxidase potential tested. The aim of this study was to compare the inhibitory activity of xanthine oxidase from methanol-
Anam, K. (Khairul)+2 more
core
Xanthine oxidase/hydrogen peroxide generates sulfur trioxide anion radical (SO.−3) from sulfite (SO2−3) [PDF]
In the presence of hydrogen peroxide (H2O2), xanthine oxidase has been found to catalyze sulfur trioxide anion radical (SO.−3) formation from sulfite anion (SO2−3).
Dalal, N.S., Shi, Xianglin, Sun, Xiaoya
core +1 more source
Allopurinol use yields potentially beneficial effects on inflammatory indices in those with recent ischemic stroke: a randomized, double-blind, placebo-controlled trial [PDF]
<p><b>Background and Purpose</b>: Elevated serum uric acid level is associated with poor outcome and increased risk of recurrent events after stroke.
Dawson, J.+6 more
core +1 more source