Results 151 to 160 of about 38,964 (184)

Xanthine oxidoreductase activity in human liver disease

The American Journal of Gastroenterology, 2002
The aim of this study was to investigate the level and the form of xanthine oxidoreductase (XOR) in severely diseased human livers, to ascertain whether the modifications of the enzyme activity reported in experimental pathology also occur in human liver disease.Total, dehydrogenase, and oxidase activities of XOR were measured in samples of human liver
STIRPE F, RAVAIOLI M, BATTELLI MG, MUSIANI S, GRAZI G   +4 more
openaire   +4 more sources

Enhanced expression and activity of xanthine oxidoreductase in failing heart

Journal of Molecular and Cellular Cardiology, 2000
The molecular basis for heart failure is unknown, but oxidative stress is associated with the pathogenesis of the disease. We tested the hypothesis that the activity of xanthine oxidoreductase (XOR), a free-radical generating enzyme, increases in hypertrophied and failing heart.
J. W. de, R. G. Schoemaker, R. d. Jonge, P. Bernocchi, E. Keijzer, R. Harrison, H. S. Sharma, CECONI, Claudio   +7 more
openaire   +5 more sources

[Inhibitors of xanthine oxidoreductase].

Nihon rinsho. Japanese journal of clinical medicine, 2008
Inhibitors of xanthine oxidoreductase decrease production of uric acid, thus they act as hypouricemic drugs. Allopurinol, a prototypical xanthine oxidoreductase inhibitor, has been widely prescribed for treatment of gout and hyperuricemia. However, severe side effects of allopurinol may occur in patients with renal insufficiency.
openaire   +1 more source

Xanthine Oxidoreductase in the Pathogenesis of Endothelial Dysfunction: An Update

Current Hypertension Reviews
Abstract:Xanthine oxidoreductase (XOR) is a rate-limiting enzyme in the formation of uric acid (UA) and is involved in the generation of reactive oxygen species (ROS). Overproduction of ROS has been linked to the pathogenesis of hypertension, atherosclerosis, and cardiovascular disease, with multiple studies over the last 30 years demonstrating that ...
Rajat Mudgal, Sanjiv Singh
openaire   +2 more sources

Xanthine oxidoreductase: dehydrogenase to oxidase conversion

Biochemical Society Transactions, 1997
M G, Ryan, A, Balendran, R, Harrison, A, Wolstenholme, G B, Bulkley   +4 more
openaire   +2 more sources

The xanthine oxidoreductase gene: structure and regulation

Biochemical Society Transactions, 1997
M, Terao, M, Kurosaki, S, Zanotta, E, Garattini   +3 more
openaire   +2 more sources

Xanthine Oxidoreductase Deficiency

2009
Deborah Bartholdi, Albert Schinzel, Deborah Bartholdi, Albert Schinzel, Deborah Bartholdi, Albert Schinzel, Deborah Bartholdi, Albert Schinzel, Anthony M. Marinaki, H. Anne Simmonds, Keiya Tada, Yoichi Matsubara, Mark Berneburg, Thomas Schwarz   +13 more
openaire   +1 more source

Xanthine Oxidoreductase

RCSB Protein Data Bank, 2009
openaire   +1 more source

HISTORY OF MILK XANTHINE OXIDOREDUCTASE

Biochemical Society Transactions, 1997
V. MASSEY, C. H. HARRIS
openaire   +1 more source

Human xanthine oxidoreductase: in search of a function

Biochemical Society Transactions, 1997
openaire   +2 more sources