Results 61 to 70 of about 38,964 (184)

The role of conjunctival epithelial cell xanthine oxidoreductase/xanthine oxidase in oxidative reactions on the ocular surface of dry eye patients with sjögren`s syndrome [PDF]

, 2007
Previous papers examined lipid peroxidase levels and myeloperoxidase activity as products of oxidative and inflammatory reactions in the tear fluid of patients suffering from dry eye.
Ardan, T., Simonová, Z., Jirsova, K., Malec, J., Dotrelová, D., Jechová, G., Brunová, B., Cejka, C., Cejkova, J., Filipec, M.   +9 more
core  

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

Targeted Mutagenesis Reveals Noncanonical Genetic Requirements for Carbon Monoxide Oxidation

Environmental Microbiology, Volume 28, Issue 11, November 2026.
Using targeted mutagenesis, this study shows that form II CODH does not contribute to CO oxidation in the model carboxydovore Paraburkholderia terrae COX and reveals that canonical maturation pathways are not universally conserved. These findings refine genome‐based predictions of microbial metabolism and improve understanding of metalloenzyme assembly
R. A. Dawson, M. Hernández
wiley   +1 more source

Uric Acid and Xanthine Oxidoreductase in Wound Healing

Current Rheumatology Reports, 2013
Chronic wounds are an important health problem because they are difficult to heal and treatment is often complicated, lengthy and expensive. For a majority of sufferers the most common outcomes are long-term immobility, infection and prolonged hospitalisation.
Fernandez, Melissa, Upton, Zee, Shooter, Gary   +2 more
openaire   +3 more sources

Localization of xanthine oxidoreductase activity using the tissue protectant polyvinyl alcohol and final electron acceptor Tetranitro BT.

, 1991
We have detected xanthine oxidoreductase activity in unfixed cryostat sections of rat and chicken liver, rat duodenum, and bovine mammary gland using the tissue protectant polyvinyl alcohol, the electron carrier 1-methoxyphenazine methosulfate, the ...
R Gossrau, W M Frederiks, A Kooij, C J Van Noorden   +3 more
core   +1 more source

Targeting Liver Xor by GalNAc-siRNA Is an Effective Strategy for Hyperuricemia Therapy

Pharmaceutics
Hyperuricemia, i.e., increased plasma uric acid concentration, is a common problem in clinical practice, leading to gout or nephrolithiasis, and is associated with other disorders, such as metabolic syndrome, cardiovascular disease, and chronic renal ...
Huiyan Sun, Xinxia Wang, Yongqiang Li, Yingzhi Shen, Lin Zhang, Yingjie Xu, Junling Liu, Xuemei Fan   +7 more
doaj   +1 more source

Metabolomics analysis elucidates unique influences on purine / pyrimidine metabolism by xanthine oxidoreductase inhibitors in a rat model of renal ischemia-reperfusion injury

Molecular Medicine, 2019
Background Clinically applied as anti-gout drugs, xanthine oxidoreductase (XOR) inhibitors, especially the potent, selective, non-purine-analog XOR inhibitors febuxostat and topiroxostat, exert organ-protective effects.
Takashi Tani, Ken Okamoto, Megumi Fujiwara, Akira Katayama, Shuichi Tsuruoka   +4 more
doaj   +1 more source

Vaccinium virgatum Aiton Leaves Extract Suppressed Lipid Accumulation and Uric Acid Production in 3T3-L1 Adipocytes

Plants, 2021
Blueberry (Vaccinium virgatum Aiton; Kinisato 35 Gou) leaves have recently attracted increasing attention as a useful material for the prevention of lifestyle diseases.
Masao Yamasaki, Yusei Kiue, Kento Fujii, Moe Sushida, Yumi Yamasaki, Kazuhiro Sugamoto, Yosuke Suzuki, Yasuko Koga, Hisato Kunitake, Hisahiro Kai, Kenjiro Ogawa, Kazuo Nishiyama, Yo Goto, Takayuki Nakayama   +13 more
doaj   +1 more source

Ultra‐Weak Photon Emission as a By‐Product of Mitochondrial Oxidative Metabolism: Mechanisms, Limits, and Implications

Nanophotonics, Volume 15, Issue 20, 27 October 2026.
Mitochondrial oxidative metabolism generates ROS. Downstream chemiexcitation triplet carbonyls, singlet oxygen; produces ultra‐weak photon emission (UPE). Energetic bounds restrict well‐coupled respiration to extremely weak, red/NIR‐biased emission. Stronger visible UPE indicates elevated oxidative flux, linking measured photon counts to redox state ...
Samuel Crowther, Alice Attenborough, Frank Vollmer   +2 more
wiley   +1 more source

The role of urate and xanthine oxidase in vascular oxidative stress:Future directions [PDF]

, 2009
Vascular oxidative stress has been shown to be a potent factor in the pathophysiology of endothelial dysfunction. Despite current optimal evidence-based therapy, mortality from various cardiovascular disorders remains high.
Allan Struthers, Jacob George, George, Jacob, Struthers, Allan   +3 more
core   +1 more source