Metabolic Impact of XOR Inhibitors Use and Discontinuation
Xanthine oxidoreductase (XOR) is the only enzyme responsible for uric acid production and is essential for preventing gout. While XOR inhibitors effectively reduce serum urate levels, they also influence purine salvage and de novo pathways, as well as ...
Mai Sekine, Kimiyoshi Ichida
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Uric Acid as a Redox Switch in Gout: Linking Xanthine Oxidoreductase-Derived ROS, NLRP3 Inflammasome Activation and Emerging Ferroptotic Mechanisms. [PDF]
Petrov PP +4 more
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Therapeutic Strategies for Hyperuricemia: From Small-Molecule Inhibitors to RNA Therapeutics. [PDF]
Yu X, Zhang M, Huang Y.
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Implication of xanthine oxidoreductase in oxidative stress-related chronic diseases. [PDF]
Nelson KL, Voruganti VS.
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Increased Xanthine Oxidoreductase Activity in Patients With Systemic Sclerosis-Associated Pulmonary Arterial Hypertension. [PDF]
Coursen JC +8 more
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Beyond Urease: New Potential Enzymatic Targets in <i>Helicobacter pylori</i>. [PDF]
Camini AM +6 more
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Mechanism of xanthine oxidase in flap ischemia-reperfusion injury and advances in targeted therapy: a mini review. [PDF]
Jia W, Wei X, Gong X.
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Colon-Specific Delivery of Febuxostat via an Amino Acid Conjugate Enhances Anti-Colitis Efficacy and Limits Systemic Exposure. [PDF]
Kim S, Ju S, Jung Y.
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