Results 81 to 90 of about 689,556 (183)

The role of conjunctival epithelial cell xanthine oxidoreductase/xanthine oxidase in oxidative reactions on the ocular surface of dry eye patients with sjögren`s syndrome [PDF]

, 2007
Previous papers examined lipid peroxidase levels and myeloperoxidase activity as products of oxidative and inflammatory reactions in the tear fluid of patients suffering from dry eye.
Ardan, T., Simonová, Z., Jirsova, K., Malec, J., Dotrelová, D., Jechová, G., Brunová, B., Cejka, C., Cejkova, J., Filipec, M.   +9 more
core  

Mechanism of Urinary Bladder Carcinogenesis Induced by a Xanthine Oxidoreductase Inhibitor, in Rats

, 2013
None
Naoki Naoki Ashizawa, Takeo Shimo
openaire   +3 more sources

Targeting Liver Xor by GalNAc-siRNA Is an Effective Strategy for Hyperuricemia Therapy

Pharmaceutics
Hyperuricemia, i.e., increased plasma uric acid concentration, is a common problem in clinical practice, leading to gout or nephrolithiasis, and is associated with other disorders, such as metabolic syndrome, cardiovascular disease, and chronic renal ...
Huiyan Sun, Xinxia Wang, Yongqiang Li, Yingzhi Shen, Lin Zhang, Yingjie Xu, Junling Liu, Xuemei Fan   +7 more
doaj   +1 more source

Possible Use of Non-purine Selective Xanthine Oxidoreductase Inhibitors for Prevention of Exercise-induced Acute Kidney Injury Associated with Renal Hypouricemia. [PDF]

Intern Med, 2023
Aizawa C, Okabe M, Takahashi D, Sagasaki M, Watanabe M, Fujimoto T, Yoshioka Y, Katsuma A, Kimura A, Miyamoto D, Sato N, Okamoto K, Ichida K, Miyazaki Y, Yokoo T.   +14 more
europepmc   +1 more source

The mechanisms of hyperuricaemia and gout, and its treatment with xanthine oxidoreductase inhibitors.

, 2016
Hyperuricaemia (serum urate (SU) concentrations ≥ 0.42 mmol/L) is the most important risk factor for gout, a common form of inflammatory arthritis. First choice treatment for gout is the xanthine oxidoreductase (XOR) inhibitor, allopurinol. Febuxostat recently became the second member of this class.
openaire   +2 more sources

Xanthine Oxidoreductase Inhibitors Suppress the Onset of Exercise-Induced AKI in High HPRT Activity Urat1-Uox Double Knockout Mice. [PDF]

J Am Soc Nephrol, 2022
Hosoya T, Uchida S, Shibata S, Tomioka NH, Matsumoto K, Hosoyamada M.   +5 more
europepmc   +1 more source

Chemical structure of xanthine and the 10 compounds studied as potential xanthine crystallization inhibitors.

, 2018
Chemical structure of xanthine and the 10 compounds studied as potential xanthine crystallization inhibitors.
Adrian Rodriguez (647760), Felix Grases (5661043), Antonia Costa-Bauza (647761), Joan Roig (5698088)   +3 more
core   +1 more source

Quantitative in situ analysis of xanthine oxidoreductase activity in rat liver. [PDF]

, 1995
The tetrazolium salt method previously developed for the detection of xanthine oxidoreductase activity in unfixed cryostat sections has been validated for quantitative purposes.
K S Bosch, W M Frederiks, A Kooij
core   +1 more source

The role of xanthine oxidoreductase and uric acid in metabolic syndrome [PDF]

, 2018
Xanthine oxidoreductase (XOR) could contribute to the pathogenesis of metabolic syndrome through the oxidative stress and the inflammatory response induced by XOR-derived reactive oxygen species and uric acid.
Bolognesi, Andrea, Letizia Polito, Polito, Letizia, Andrea Bolognesi, Battelli, Maria Giulia, Massimo Bortolotti, Bortolotti, Massimo, Maria Giulia Battelli   +7 more
core   +1 more source

Metabolic syndrome and cancer risk: The role of xanthine oxidoreductase [PDF]

, 2019
Obesity and related pathologies such as diabetes and metabolic syndrome are associated with chronic inflammation and cancer. The serum level of xanthine oxidoreductase (XOR) is correlated to obesity-associated metabolic disorders.
Letizia Polito, Bolognesi, Andrea, Polito, Letizia, Andrea Bolognesi, Battelli, Maria Giulia, Massimo Bortolotti, Bortolotti, Massimo, Maria Giulia Battelli   +7 more
core   +1 more source