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Critical Roles of a Dendritic Cell Subset Expressing a Chemokine Receptor, XCR1
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XCL1 and XCR1 in the immune system
Microbes and Infection, 2012XCL1, a C class chemokine also known as lymphotactin, is produced by T, NK, and NKT cells during infectious and inflammatory responses, whereas XCR1, the receptor of XCL1, is expressed by a dendritic cell subpopulation. The XCL1-XCR1 axis plays an important role in dendritic-cell-mediated cytotoxic immune response.
Yousuke Takahama
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Functional expression of the chemokine receptor XCR1 on oral epithelial cells
Journal of Pathology, 2010AbstractChemokines are chemoattractant cytokines which act on specific receptors and play an important role in leukocyte migration as well as physiological and pathological processes. We investigated the role of the chemokine receptor XCR1 and its ligand lymphotactin (Lptn/XCL1) in the regulation of oral epithelial cell behaviour.
Simon A Whawell, Craig Murdoch
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Conservation of a chemokine system, XCR1 and its ligand, XCL1, between human and mice
Biochemical and Biophysical Research Communications, 2010Understanding dendritic cell (DC) subset functions should lead to the development of novel types of vaccine. Here we characterized expression of XC chemokine receptor 1 (XCR1) and its ligand, XCL1. Murine XCR1 was the only chemokine receptor selectively expressed in CD8alpha(+) conventional DCs.
Katsuaki Hoshino, Tsuneyasu Kaisho
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The Journal of Immunology, 2021
Abstract West Nile Virus (WNV) is a leading cause of mosquito-borne neuroinvasive disease in the US. Following infection, WNV can cause neuronal injury and disease. Previous studies have shown that the proper activation of virus-specific T cells results in protection from WNV infection and any associated disease.
Douglas M Durrant +2 more
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Abstract West Nile Virus (WNV) is a leading cause of mosquito-borne neuroinvasive disease in the US. Following infection, WNV can cause neuronal injury and disease. Previous studies have shown that the proper activation of virus-specific T cells results in protection from WNV infection and any associated disease.
Douglas M Durrant +2 more
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Magnetic properties of Co2-xCr1+xAl (x=0,0.4)
AIP Conference Proceedings, 2020Co2-xCr1+xAl for x=0 and 0.4 (x=0.4 means 20% of Co atoms of Co2CrAl have been replaced by Cr atoms) have been prepared in tri-arc melting furnace. XRD pattern with Reitveld refinement analysis of both samples indicate Heusler alloy like L21 structure with B2 disorder. It is revealed by Magnetization measurement that both compounds show paramagnetic to
Amrita Datta +2 more
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XCR1+ Conventional Dendritic Cell Dynamics and Modulation in Liver Ischemia-Reperfusion Injury
American Journal of TransplantationT.B. Ngo +6 more
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