Results 21 to 30 of about 3,980 (196)

Regional and Compartmental Changes Drive Progressive Patterns of Striatal Degeneration in X-Linked Dystonia Parkinsonism. [PDF]

Ann Neurol
Objective Initially described in 1976, X‐linked dystonia parkinsonism (XDP) is a neurodegenerative disease that can be characterized by the presentation of dystonia and parkinsonism symptoms. Although this disease bears some resemblance to other neurodegenerative diseases in terms of symptomatology, the pathological signature of XDP is still unclear ...
Tan AYS, Thai NSSS, Arasaratnam CJ, Han SA, Penney EB, Acuña-Sunshine G, Diesta CCE, Ang MC, Muñoz E, Fernandez-Cerado C, Cleofas V, Legarda GP, Velasco S, Sy MA, Turner CP, Dragunow M, Curtis MA, Graybiel AM, Faull RLM, Singh-Bains MK.   +19 more
europepmc   +2 more sources

Enhance the multipath connection using AF XDP sockets

2024 International Conference on Information Networking (ICOIN)
7883Multipath is a technique that utilizes multiple links to establish an abstracted, unified connection for upper-level applications. This type of connection offers distinct advantages regarding overall bandwidth and reliability compared to regular ...
Ba Que Le, Mathias Santos de Brito, Elena-Ramona Modroiu, Marius Corici, Thomas Magedanz   +4 more
openaire   +2 more sources

Neuroimaging and neuropathology studies of X-linked dystonia parkinsonism

Neurobiology of Disease, 2021
X-linked Dystonia Parkinsonism (XDP) is a recessive, genetically inherited neurodegenerative disorder endemic to Panay Island in the Philippines. Clinical symptoms include the initial appearance of dystonia, followed by parkinsonian traits after 10–15 ...
Christine J. Arasaratnam, Malvindar K. Singh-Bains, Henry J. Waldvogel, Richard L.M. Faull   +3 more
doaj   +1 more source

A Cross-Cultural Validation of the Filipino and Hiligaynon Versions of the Parts IIIB (Non-Motor Features) and IV (Activities of Daily Living) of the X-Linked Dystonia-Parkinsonism– MDSP Rating Scale

Clinical Parkinsonism & Related Disorders, 2021
Introduction: X-linked dystonia-parkinsonism (XDP) is a progressive movement disorder which also encompasses non-motor features and alterations in activities of daily living.
Richelle Ann S. Santiano, Raymond L. Rosales   +1 more
doaj   +1 more source

Plasma levels of leucocyte elastase-generated cross linked fibrin degradation products (E-XDP) are elevated in chronic venous disease.

PLoS ONE, 2021
Patients with chronic venous disease (CVD) have elevated levels of leucocyte elastase (LE) released from the activation of leucocytes. In acute deep venous thrombosis (DVT), LE can degrade fibrin from the thrombus resulting in cross-linked fibrin ...
Helen Sinabulya, Angela Silveira, Lena Blomgren, Joy Roy   +3 more
doaj   +1 more source

Neuroinflammation and histone H3 citrullination are increased in X-linked Dystonia Parkinsonism post-mortem prefrontal cortex

Neurobiology of Disease, 2020
Neuroinflammation plays a pathogenic role in neurodegenerative diseases and recent findings suggest that it may also be involved in X-linked Dystonia-Parkinsonism (XDP) pathogenesis.
Tiziana Petrozziello, Alexandra N. Mills, Christine A. Vaine, Ellen B. Penney, Cara Fernandez-Cerado, Gierold Paul A. Legarda, M. Salvie Velasco-Andrada, Patrick J. Acuña, Mark A. Ang, Edwin L. Muñoz, Cid Czarina E. Diesta, Regina Macalintal-Canlas, Geraldine Acuña-Sunshine, Laurie J. Ozelius, Nutan Sharma, D. Cristopher Bragg, Ghazaleh Sadri-Vakili   +16 more
doaj   +1 more source

Tissue-specific and repeat length-dependent somatic instability of the X-linked dystonia parkinsonism-associated CCCTCT repeat

Acta Neuropathologica Communications, 2022
X-linked dystonia-parkinsonism (XDP) is a progressive adult-onset neurodegenerative disorder caused by insertion of a SINE-VNTR-Alu (SVA) retrotransposon in the TAF1 gene.
Lindsey N. Campion, Alan Meijia Maza, Rachita Yadav, Ellen B. Penney, Micaela G. Murcar, Kevin Correia, Tammy Gillis, Cara Fernandez-Cerado, M. Salvie Velasco-Andrada, G. Paul Legarda, Niecy G. Ganza-Bautista, J. Benedict B. Lagarde, Patrick J. Acuña, Trisha Multhaupt-Buell, Gabrielle Aldykiewicz, Melanie L. Supnet, Jan K. De Guzman, Criscely Go, Nutan Sharma, Edwin L. Munoz, Mark C. Ang, Cid Czarina E. Diesta, D. Cristopher Bragg, Laurie J. Ozelius, Vanessa C. Wheeler   +24 more
doaj   +1 more source

Modeling X-Linked Dystonia Parkinsonism (XDP) in Patient-Derived Medium Spiny Neurons

, 2023
X-linked dystonia-parkinsonism (XDP) is an adult-onset neurodegenerative disorder that results in the loss of striatal medium spiny neurons (MSNs). XDP is an X-linked disorder caused by disease-specific mutations around the TAF1 gene.
Aryal, Shivani
core   +1 more source

Analysis of Linux OS security tools for packet filtering and processing

Mokslas: Lietuvos Ateitis, 2021
Open-source software and its components are widely used in various products, solutions, and applications, even in closed-source. Majority of them are made on Linux or Unix based systems. Netfilter framework is one of the examples.
Dmitrij Melkov, Šarūnas Paulikas
doaj   +1 more source

X-linked Dystonia-Parkinsonism patient cells exhibit altered signaling via nuclear factor-kappa B

Neurobiology of Disease, 2017
X-linked Dystonia-Parkinsonism (XDP) is a progressive neurodegenerative disease involving the loss of medium spiny neurons within the striatum. An XDP-specific haplotype has been identified, consisting of seven sequence variants which cluster around the ...
Christine A. Vaine, David Shin, Christina Liu, William T. Hendriks, Jyotsna Dhakal, Kyle Shin, Nutan Sharma, D. Cristopher Bragg   +7 more
doaj   +1 more source