Results 41 to 50 of about 3,980 (196)

Laser-induced damage in XDP materials

Electronics Letters, 1971
Pulsed-laser damage in XDP electro-optic crystals, occurring at energy densities ≤ 2J/cm2, has been related to the presence of micrometer-sized inclusions. For material free of these inclusions damage occurs by self-focusing mechanisms at power densities of approximately 20GW/cm2.
T.M. Christmas, J.M. Ley
openaire   +1 more source

Extended Berkeley Packet Filter: An Application Perspective

IEEE Access, 2022
The extended Berkeley Packet Filter (eBPF) is a lightweight and fast 64-bit RISC-like virtual machine (VM) inside the Linux kernel. eBPF has emerged as the most promising and de facto standard of executing untrusted, user-defined specialized code at run ...
Husain Sharaf, Imtiaz Ahmad, Tassos Dimitriou   +2 more
doaj   +1 more source

A scalable workflow for sensitive detection and genomic profiling of tumour cells in lymph nodes from FFPE tissue

The Journal of Pathology, EarlyView.
Abstract Accurate detection of lymph node (LN) metastases is critical for prognosis and surgical decision‐making in head and neck squamous cell carcinoma (HNSCC) and other epithelial cancers. Standard histopathology examines only a small fraction of LN tissue, limiting sensitivity for micrometastases and isolated tumour cells.
Tristan Bergmann, Marianne Hölbling, Monica Sudarsanam, Christiane Driemel, Maximilian E Daniels, Joanna Swierz, Sandra Jaschinski, Maximilian Seidl, Norbert R Kübler, Wolfram T Knoefel, Rui PL Neves, Karl C Sproll, Nikolas H Stoecklein   +12 more
wiley   +1 more source

SVA insertion in X-linked Dystonia Parkinsonism alters histone H3 acetylation associated with TAF1 gene.

PLoS ONE, 2020
X-linked Dystonia-Parkinsonism (XDP) is a neurodegenerative disease linked to an insertion of a SINE-VNTR-Alu (SVA)-type retrotransposon within an intron of TAF1.
Tiziana Petrozziello, Amanda M Dios, Kaly A Mueller, Christine A Vaine, William T Hendriks, Kelly E Glajch, Alexandra N Mills, Kotchaphorn Mangkalaphiban, Ellen B Penney, Naoto Ito, Cara Fernandez-Cerado, Gierold Paul A Legarda, M Salvie Velasco-Andrada, Patrick J Acuña, Mark A Ang, Edwin L Muñoz, Cid Czarina E Diesta, Regina Macalintal-Canlas, Geraldine Acuña, Nutan Sharma, Laurie J Ozelius, D Cristopher Bragg, Ghazaleh Sadri-Vakili   +22 more
doaj   +1 more source

Fast Packet Processing with eBPF and XDP

ACM Computing Surveys, 2020
Extended Berkeley Packet Filter (eBPF) is an instruction set and an execution environment inside the Linux kernel. It enables modification, interaction, and kernel programmability at runtime. eBPF can be used to program the eXpress Data Path (XDP), a kernel network layer that processes packets closer to the NIC for fast packet processing.
Marcos Augusto M. Vieira, Matheus S. Castanho, Racyus D. G. Pacífico, Elerson Rubens da Silva Santos, Eduardo P. M. Câmara Júnior, Luiz Filipe M. Vieira   +5 more
openaire   +1 more source

Derivation of Mouse Dome‐Shaped Trophoblast Stem Cells With Low Heterogeneity From Blastocysts

Cell Proliferation, EarlyView.
Here, Liu et al. report the generation of mouse dome‐shaped trophoblast stem cells (dTSCs) with low heterogeneity and autonomous differentiation potential. dTSCs robustly generate all trophoblast lineages in vitro and contribute to the placenta in vivo, providing a refined model for studying trophoblast development and related disorders.
Minli Liu, Shaofang Ren, Xinyu Xia, Guanlin Lu, Haojie Yang, Yi Zheng, Jiexiang Zhao, Xiao‐Yang Zhao, Mei Wang   +8 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, Volume 20, Issue 11, Page 2611-2623, November 2026.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

CCL5 and GLUT1 define leader cells in collective invasion of colorectal cancer

The Journal of Pathology, Volume 270, Issue 3, Page 288-302, November 2026.
Abstract Invasion and metastasis in multiple solid tumors are promoted by collective invasion which is organized by leader and follower cells. Yet in colorectal cancer (CRC), biomarkers and mechanisms that specify leader cells remain undefined. Here we identify biomarkers of leader cells and elucidate how they drive CRC collective invasion and ...
Zhaowen Zhang, Jiaying Tan, Zhicheng Zeng, Xiaohui Zhu, Liyao Mai, Yao Yin, Yuting Huang, Wei Kang, Honghui Jiang, Shaowan Xu, Yanqing Ding, Xinghua Pan, Feifei Wang, Li Liang   +13 more
wiley   +1 more source

Model Control and Digital Implementation of the Three Phase Interleaved Parallel Bidirectional Buck–Boost Converter for New Energy Electric Vehicles

Energies, 2022
In recent years, the imminent environmental problems and increasing attention to the global energy crisis have prompted the need for new opportunities and technologies to meet higher demands for clean and sustainable energy systems.
Chi Zhang, Binyue Xu, Jasronita Jasni, Mohd Amran Mohd Radzi, Norhafiz Azis, Qi Zhang   +5 more
doaj   +1 more source

ATL2 Recruits TRAK1 to Promote Mitochondrial Transport at ER–Mitochondria Contact Sites

Advanced Science, Volume 13, Issue 60, 28 October 2026.
ABSTRACT Mitochondrial transport and distribution are crucial for cellular homeostasis, yet whether and how they are regulated by endoplasmic reticulum (ER)–mitochondria contact sites remains unclear. Here, we demonstrate that the ER protein atlastin‐2 (ATL2) orchestrates mitochondrial transport and distribution by promoting assembly of the transport ...
Yiru Cheng, Peiyuan Chai, Xiayuhe Pei, Yiwen Chen, Xiaoshuai Huang, Bei Liu, Yiqian Wu, Junlin Teng, Pengli Zheng, Jianguo Chen   +9 more
wiley   +1 more source