Decreased N-TAF1 expression in X-linked dystonia-parkinsonism patient-specific neural stem cells
Disease Models & Mechanisms, 2016 X-linked dystonia-parkinsonism (XDP) is a hereditary neurodegenerative disorder involving a progressive loss of striatal medium spiny neurons. The mechanisms underlying neurodegeneration are not known, in part because there have been few cellular models ...
Naoto Ito +12 more
doaj +1 more source
Modeling X-Linked Dystonia Parkinsonism (XDP) in Patient-Derived Medium Spiny Neurons
, 2023 X-linked dystonia-parkinsonism (XDP) is an adult-onset neurodegenerative disorder that results in the loss of striatal medium spiny neurons (MSNs). XDP is an X-linked disorder caused by disease-specific mutations around the TAF1 gene.
Aryal, Shivani
core +1 more source
X-Linked Dystonia Parkinsonism: Clinical Phenotype, Genetics and Therapeutics [PDF]
Journal of Movement Disorders, 2010 The clinical phenotype of X-Linked Dystonia Parkinsonism (XDP) is typically one that involves a Filipino adult male whose ancestry is mostly traced in the Philippine island of Panay.
Raymond L. Rosales
doaj +1 more source
Detection of Denial of Service Attack in Cloud Based Kubernetes Using eBPF
Applied Sciences, 2023 Kubernetes is an orchestration tool that runs and manages container-based workloads. It works as a collection of different virtual or physical servers that support multiple storage capacities, provide network functionalities, and keep all containerized ...
Amin Sadiq +5 more
doaj +1 more source
Український журнал військової медицини, 2023 Мета. Обґрунтування вибору носія для субстанції калини звичайної плодів екстракту рідкого (КЗПЕР) у складі розроблюваних таблеток під умовною назвою «Вібурнікор» мембраностабілізувальної та кардіопротекторної. Матеріали та методи.
A. O. Yaroshenko, O. S. Shpychak
doaj +1 more source
Proteomic analysis of X-linked dystonia parkinsonism disease striatal neurons reveals altered RNA metabolism and splicing. [PDF]
Neurobiol DisSummary: X-linked dystonia-parkinsonism (XDP) is a rare neurodegenerative disease endemic to the Philippines. The genetic cause for XDP is an insertion of a SINE-VNTR-Alu (SVA)-type retrotransposon within intron 32 of TATA-binding protein associated ...
Tshilenge KT +11 more
europepmc +2 more sources
Cost-Analysis of the Different Treatment Modalities in X-Linked Dystonia–Parkinsonism
Frontiers in Neurology, 2019 Background: X-linked dystonia-parkinsonism (XDP) is a debilitating disease endemic in the Philippines. Several oral medications as well as botulinum toxin A (BoNT-A) injection and deep brain stimulation (DBS) surgery appear to be the cornerstone of ...
Ranhel C. De Roxas +2 more
doaj +1 more source
Validation of a Questionnaire for Distinguishing X-Linked Dystonia Parkinsonism From Its Mimics
Frontiers in Neurology, 2018 Objectives: X-linked dystonia parkinsonism (XDP) is a neurodegenerative movement disorder endemic to the island of Panay in the Philippines. We undertook a population-based prevalence study to enumerate all cases of XDP in Panay.
Jose Danilo B. Diestro +3 more
doaj +1 more source
Increased insula-putamen connectivity in X-linked dystonia-parkinsonism
NeuroImage: Clinical, 2018 Preliminary evidence from postmortem studies of X-linked dystonia-parkinsonism (XDP) suggests tissue loss may occur first and/or most severely in the striatal striosome compartment, followed later by cell loss in the matrix compartment.
Anne J. Blood +9 more
doaj +1 more source
Extended Berkeley Packet Filter: An Application Perspective
IEEE Access, 2022 The extended Berkeley Packet Filter (eBPF) is a lightweight and fast 64-bit RISC-like virtual machine (VM) inside the Linux kernel. eBPF has emerged as the most promising and de facto standard of executing untrusted, user-defined specialized code at run ...
Husain Sharaf +2 more
doaj +1 more source