Results 31 to 40 of about 3,980 (196)

Decreased N-TAF1 expression in X-linked dystonia-parkinsonism patient-specific neural stem cells

open access: yesDisease Models & Mechanisms, 2016
X-linked dystonia-parkinsonism (XDP) is a hereditary neurodegenerative disorder involving a progressive loss of striatal medium spiny neurons. The mechanisms underlying neurodegeneration are not known, in part because there have been few cellular models ...
Naoto Ito   +12 more
doaj   +1 more source

X-Linked Dystonia Parkinsonism: Clinical Phenotype, Genetics and Therapeutics [PDF]

open access: yesJournal of Movement Disorders, 2010
The clinical phenotype of X-Linked Dystonia Parkinsonism (XDP) is typically one that involves a Filipino adult male whose ancestry is mostly traced in the Philippine island of Panay.
Raymond L. Rosales
doaj   +1 more source

Detection of Denial of Service Attack in Cloud Based Kubernetes Using eBPF

open access: yesApplied Sciences, 2023
Kubernetes is an orchestration tool that runs and manages container-based workloads. It works as a collection of different virtual or physical servers that support multiple storage capacities, provide network functionalities, and keep all containerized ...
Amin Sadiq   +5 more
doaj   +1 more source

Transcranial magnetic resonance-guided focused ultrasound pallidothalamic tractotomy for patients with X-linked dystonia-parkinsonism: a study protocol

open access: yesBMC Neurology, 2023
Transcranial magnetic resonance-guided focused ultrasound (MRgFUS) is a noninvasive method for controlling tremor and has recently been used in patients with X-linked dystonia-parkinsonism (XDP).
Roland Dominic G. Jamora   +5 more
doaj   +1 more source

Design and implementation of an XDP-based framework for application-layer real-time packet scheduling

open access: yes, 2023
Die rasante Entwicklung von Netzwerktechnologien und Anwendungen hat zu immer höheren Anforderungen an Netzwerkleistung und -effizienz geführt. Der Linux eXpress Data Path (XDP) hat sich als eine leistungsstarke und flexible Technologie zur Verbesserung ...
Hafner, Marcel
core   +1 more source

Обґрунтування вибору носія для субстанції калини звичайної плодів екстракту рідкого у складі таблеток «Вібурнікор»

open access: yesУкраїнський журнал військової медицини, 2023
Мета. Обґрунтування вибору носія для субстанції калини звичайної плодів екстракту рідкого (КЗПЕР) у складі розроблюваних таблеток під умовною назвою «Вібурнікор» мембраностабілізувальної та кардіопротекторної. Матеріали та методи.
A. O. Yaroshenko, O. S. Shpychak
doaj   +1 more source

Cost-Analysis of the Different Treatment Modalities in X-Linked Dystonia–Parkinsonism

open access: yesFrontiers in Neurology, 2019
Background: X-linked dystonia-parkinsonism (XDP) is a debilitating disease endemic in the Philippines. Several oral medications as well as botulinum toxin A (BoNT-A) injection and deep brain stimulation (DBS) surgery appear to be the cornerstone of ...
Ranhel C. De Roxas   +2 more
doaj   +1 more source

Validation of a Questionnaire for Distinguishing X-Linked Dystonia Parkinsonism From Its Mimics

open access: yesFrontiers in Neurology, 2018
Objectives: X-linked dystonia parkinsonism (XDP) is a neurodegenerative movement disorder endemic to the island of Panay in the Philippines. We undertook a population-based prevalence study to enumerate all cases of XDP in Panay.
Jose Danilo B. Diestro   +3 more
doaj   +1 more source

Increased insula-putamen connectivity in X-linked dystonia-parkinsonism

open access: yesNeuroImage: Clinical, 2018
Preliminary evidence from postmortem studies of X-linked dystonia-parkinsonism (XDP) suggests tissue loss may occur first and/or most severely in the striatal striosome compartment, followed later by cell loss in the matrix compartment.
Anne J. Blood   +9 more
doaj   +1 more source

Substrate Specificity of B12-Depedent Ribonucleotide Reductases: Biotechnology and Metabolic Implications. [PDF]

open access: yesChembiochem
Ribonucleotide reductases (RNRs) are valuable biocatalysts for the biosynthesis of non‐natural deoxyribonucleotide, relevant in fields like medical science and synthetic biology. In this study, we explore the substrate spectrum of two thermostable RNRs and discuss their implications for nucleotide metabolism and biocatalytical applications ...
Eltoukhy L, Loderer C.
europepmc   +2 more sources

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