Results 51 to 60 of about 3,918 (199)
Cancer Medicine, Volume 15, Issue 9, September 2026.Single‐cell RNA sequencing of anaplastic thyroid cancer (ATC) and aggressive papillary thyroid cancer (PTC) revealed coordinated tumor‐intrinsic and immune reprogramming during thyroid cancer dedifferentiation. ATC exhibited MAPK/PI3K co‐activation, p53 suppression, E2F activation, cytotoxic lymphocyte exhaustion, enhanced regulatory T‐cell ...
Saeko Tahara +6 more
wiley +1 more source
Piroxicam Loading onto Mesoporous Silicas by Supercritical CO2 Impregnation
Molecules, 2021 Piroxicam (PRX) is a commonly prescribed nonsteroidal anti-inflammatory drug. Its efficacy, however, is partially limited by its low water solubility. In recent years, different studies have tackled this problem and have suggested delivering PRX through ...
Marta Gallo +6 more
doaj +1 more source
KPNA2 Drives Immunosuppression in Ovarian Cancer via CCL2/CCR2‐Dependent MDSC Recruitment
Cancer Science, Volume 117, Issue 9, Page 2461-2479, September 2026.KPNA2 drives intratumoral MDSC accumulation and immunosuppression in ovarian cancer via the NF‐κB/CCL2/CCR2 axis. Mechanistically, KPNA2 facilitates NF‐κB/p65 nuclear translocation and induces CCL2 transcription, recruiting MDSCs to establish an immunosuppressive microenvironment.
Qingli Li +8 more
wiley +1 more source
Comparative Study of Powder Carriers Physical and Structural Properties
Pharmaceutics, 2022 High specific surface area (SSA), porous structure, and suitable technological characteristics (flow, compressibility) predetermine powder carriers to be used in pharmaceutical technology, especially in the formulation of liquisolid systems (LSS) and ...
Klára Kostelanská +5 more
doaj +1 more source
Presence and role of DNA G-quadruplex structures in the pathogenesis of XDP [PDF]
, 2023 XDP è un malattia genetica che gli uomini possono sviluppare intorno ai 40 anni di età. Alterazioni genetiche localizzate nel cromosoma X sono alla base di questo disturbo e lo stesso aplotipo è condiviso da tutti i probandi.
NICOLETTO, GIULIA
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Cell Proliferation, Volume 59, Issue 8, August 2026.The hfPSC‐LCs could be established from naïve hESCs, conventional hESCs, hiPSCs, and human blastocysts. The hfPSC‐LCs hold robust capacity for three germ layers, hPGCLCs, and hALPCs. ABSTRACT Human embryos undergo pivotal morphogenetic remodelling shortly after implantation. The understanding of this crucial stage is severely impeded by the scarcity of
Xiaoxiao Wang +11 more
wiley +1 more source
Emerging directions in tauopathy research
Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.Abstract The Tau Global Conference 2025, hosted by the Alzheimer's Association, CurePSP, and the Rainwater Charitable Foundation, convened international experts from academia, industry, government, and philanthropy to explore advances and challenges in tauopathy research. The meeting highlighted progress across tau biology, including emerging models of
Luc Buée +41 more
wiley +1 more source
Pharmaceutics, 2020 In this paper, the role of mesoporous silica (MS) particle size in the stabilization of amorphous simvastatin (SVT) is revealed. For inhibiting recrystallization of the supercooled drug, the two MS materials (Syloid® XDP 3050 and Syloid® 244 FP) were ...
Justyna Knapik-Kowalczuk +5 more
doaj +1 more source
Movement Disorders Clinical Practice, Volume 13, Issue 6, Page 1383-1398, June 2026.ABSTRACT Background Classifying abnormal tongue movements is challenging due to their varied presentations and limited visibility compared to other body parts. Accurate identification of the phenomenology guides physical examination and can point to specific diagnoses.
Nathaniel Bendahan +4 more
wiley +1 more source
Realizzazione di firewall in Linux tramite Express Data Path (XDP) [PDF]
, 2019 In questo elaborato è stato presentato un esempio di programma XDP per eBPF con lo scopo di andare a verificare l’elaborazione veloce di pacchetti programmabili nel kernel.
Baldù, Giuseppe
core