Results 71 to 80 of about 9,272 (178)
ABSTRACT Colour polytypism represents an example of phenotypic diversification shaped by genetic divergence and ecological pressures. Poison frogs of the genus Oophaga (Dendrobatidae) are highly polytypic in coloration, making them an ideal system for investigating the genetic and physiological basis of colour variation.
Vasiliki Mantzana‐Oikonomaki +7 more
wiley +1 more source
Mixed lineage kinase domain‐like pseudokinase (MLKL) is a key effector of necroptosis. We identified an MLKL homologue from Hexagrammos otakii, named HoMLKL. The open reading frame (ORF) of HoMLKL contained 1497 nucleotides and encoded a protein with 498 amino acids (Mw = 57.15 kDa). Bioinformatic analysis revealed that HoMLKL is highly conserved.
Yuan Du +10 more
wiley +1 more source
This study investigates the deacetylation of ACLY at K978 acts as a novel risk in colorectal cancer chemoresistance. The deacetylation of K978 induces ACLY relocation to the nucleus and promotes its binding to RBM15, a m6A methylation modification “writer”.
Jun Wen +8 more
wiley +1 more source
ABSTRACT Peroxisome proliferator‐activated receptors (PPAR) are master transcriptional regulators that maintain metabolic homeostasis in vertebrates. Amphibians are often exposed to endocrine disrupting compounds (EDCs) that could dysregulate lipid metabolism.
Anna Bushong +3 more
wiley +1 more source
Comparison of induction during development between Xenopus tropicalis and Xenopus laevis
Several in vitro systems exist for the induction of animal caps using growth factors such as activin. In this paper, we compared the competence of activin-treated animal cap cells dissected from the late blastulae of Xenopus tropicalis and Xenopus laevis.
Ayako, Sedohara +2 more
openaire +3 more sources
Expression of ribosomopathy genes during Xenopus tropicalis embryogenesis [PDF]
Because ribosomes are ubiquitously required for protein production, it was long assumed that any inherited defect in ribosome manufacture would be embryonically lethal. However, several human congenital diseases have been found to be associated with mutations in ribosome biogenesis factors.
Robson, Andrew +4 more
openaire +2 more sources
Microanatomy of Dermal Roofing Bones in the Skull of Pipoid Frogs
The cranial bone microanatomy in extant and extinct aquatic pipoids and phylogenetically distant aquatic anurans were analyzed. Micro‐CT data revealed no significant differences in bone thickness and cross‐sectional area among groups, that present similar aquatic lifestyles.
Tomás Fornari, Johannes Müller
wiley +1 more source
Heart regeneration in adult Xenopus tropicalis after apical resection
Background Myocardium regeneration in adult mammals is very limited, but has enormous therapeutic potentials. However, we are far from complete understanding the cellular and molecular mechanisms by which heart tissue can regenerate.
Souqi Liao +14 more
doaj +1 more source
Mutations in the histone methyltransferase Ezh2 drive context-dependent leukemia in Xenopus tropicalis [PDF]
Dieter Tulkens +11 more
openalex +1 more source
Conserved context‐dependent cis‐regulatory elements act as a major reservoir of disease‐associated polymorphisms in the human genome and are also affected by epigenetic change. This ‘state‐of‐the‐art’ review explores the latest developments in studying these enigmatic elements and how the effects of disease‐associated polymorphisms and environmentally ...
Andrew McEwan +5 more
wiley +1 more source

