Results 81 to 90 of about 9,272 (178)

Structural Basis of GABAB Receptor Activation during Evolution

Advanced Science, Volume 12, Issue 37, October 6, 2025.
This study explores the structural and functional mechanisms of the drosophila GABAB receptor, a key role in neurotransmission. Using cryo‐EM, the research reveals how the receptor's activation differs from its human counterpart, highlighting unique evolutionary features.
Guofei Hou, Shenglan Zhang, Cangsong Shen, Suyu Ji, Binqian Zou, Chanjuan Xu, Liang Li, Dandan Shen, Jiayin Liang, Haidi Chen, Philippe Rondard, Cheng Deng, Jun He, Yan Zhang, Jianfeng Liu   +14 more
wiley   +1 more source

The Interplay of Ontogeny and Phylogeny at the Transcriptome Level of the Tetrapod Heart

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 344, Issue 6, Page 325-340, September 2025.
The main stages of development during which species‐specific heart anatomy is determined in the ontogeny of representative tetrapods. Transcriptomic similarity is expected earlier in development before heart anatomy diverges. ABSTRACT The tetrapod heart is characterized by three chambers in amphibians and non‐avian reptiles, as opposed to four in birds,
G. A. Cordero, A. K. Holloway, T. Friedrich, J. Eme, W. Eckalbar, K. Kusumi, F. J. Janzen, J. W. Hicks, F. L. Conlon, B. G. Bruneau, K. S. Pollard   +10 more
wiley   +1 more source

Comparative analysis of Xenopus tropicalis and Xenopus laevis vitellogenin gene sequences

Nucleic Acids Research, 1982
Analysis of cDNA clones synthesized from vitellogenin mRNA of X. tropicalis revealed three different types of cDNA clones, i.e. A, A* and B. A and A* clones have a sequence divergence of about 6% and are both related to X. laevis vitellogenin cDNAs of subgroup A1 as well as A2 with a sequence divergence of 6-9%.
R B, Jaggi, T, Wyler, G U, Ryffel
openaire   +3 more sources

Single‐Cell Sequencing: A Sharp Sword for Deciphering Biological Innovations and Evolutionary Adaptations in Lower Vertebrates and Invertebrates

Reviews in Aquaculture, Volume 17, Issue 4, September 2025.
Single‐cell sequencing sheds light on cellular diversity, development, and immune evolution in fish and invertebrates, offering new insights into environmental adaptation and evolutionary biology. ABSTRACT Single‐cell sequencing (SCS) technology has revolutionized the study of cellular heterogeneity by enabling the exploration of biological processes ...
Chongbin Hu, Yun Hong, Lixin Xiang, Ye Chen, Jianzhong Shao, Hangjun Zhang   +5 more
wiley   +1 more source

Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals

Nature Communications, 2019
Embryonic development produces different cell types in response to a small number of inductive signals. Here, the authors characterise how maternal factors modify chromatin to specify initial competence in Xenopus tropicalis, finding that the pioneering ...
George E. Gentsch, Thomas Spruce, Nick D. L. Owens, James C. Smith   +3 more
doaj   +1 more source

Exploring nervous system transcriptomes during embryogenesis and metamorphosis in Xenopus tropicalis using EST analysis

BMC Genomics, 2007
Background The western African clawed frog Xenopus tropicalis is an anuran amphibian species now used as model in vertebrate comparative genomics. It provides the same advantages as Xenopus laevis but is diploid and has a smaller genome of 1.7 Gbp ...
Wegnez Maurice, Perron Muriel, Demeneix Barbara A, Coen Laurent, Thuret Raphaël, Fierro Ana C, Gyapay Gabor, Weissenbach Jean, Wincker Patrick, Mazabraud André, Pollet Nicolas   +10 more
doaj   +1 more source

Xenopus tropicalis: An Ideal Experimental Animal in Amphibia

Experimental Animals, 2010
Studies using amphibians have contributed to the progress of life science including developmental biology and cell biology for more than one hundred years. Since the 1950s Xenopus laevis in particular has been used by scientists in many fields for experiments, resulting in the development of various techniques such as microsurgery on early embryos ...
Keiko, Kashiwagi, Akihiko, Kashiwagi, Atsushi, Kurabayashi, Hideki, Hanada, Keisuke, Nakajima, Morihiro, Okada, Minoru, Takase, Yoshio, Yaoita   +7 more
openaire   +3 more sources

Xenopus Resources: Transgenic, Inbred and Mutant Animals, Training Opportunities, and Web-Based Support

Frontiers in Physiology, 2019
Two species of the clawed frog family, Xenopus laevis and X. tropicalis, are widely used as tools to investigate both normal and disease-state biochemistry, genetics, cell biology, and developmental biology.
Marko Horb, Marcin Wlizla, Anita Abu-Daya, Sean McNamara, Dominika Gajdasik, Takeshi Igawa, Atsushi Suzuki, Hajime Ogino, Anna Noble, Centre de Ressource Biologique Xenope team in France, Jacques Robert, Christina James-Zorn, Matthew Guille, Matthew Guille, Morgane Nicolas, Thomas Lafond, Daniel Boujard, Yann Audic, Brigitte Guillet   +18 more
doaj   +1 more source

Nucleoporin gene expression in Xenopus tropicalis embryonic development

The International Journal of Developmental Biology, 2016
Nucleoporins (nups) compose the structure of the nuclear pore complex (NPC) of all cells, but several studies have illuminated nucleoporins' additional roles in development and the cell cycle. However, a comprehensive study of nup expression in embryonic development has not yet been reported.
Nooreen, Reza, Mustafa K, Khokha, Florencia, Del Viso   +2 more
openaire   +3 more sources

Accelerated gene evolution and subfunctionalization in the pseudotetraploid frog Xenopus laevis

BMC Biology, 2007
Background Ancient whole genome duplications have been implicated in the vertebrate and teleost radiations, and in the emergence of diverse angiosperm lineages, but the evolutionary response to such a perturbation is still poorly understood.
Grammer Timothy C, Khokha Mustafa K, Hellsten Uffe, Harland Richard M, Richardson Paul, Rokhsar Daniel S   +5 more
doaj   +1 more source