Results 121 to 130 of about 18,392 (242)

Extension of SASE bandwidth up to 2% as a way to increase the efficiency of protein structure determination by x-ray nanocrystallography at the European XFEL

, 2013
Femtosecond x-ray nanocrystallography exploiting XFEL radiation is an emerging method for protein structure determination using crystals with sizes ranging from a few tens to a few hundreds nanometers.
Geloni, Gianluca, Kocharyan, Vitali, Saldin, Evgeni, Serkez, Svitozar, Yefanov, Oleksander, Zagorodnov, Igor   +5 more
core  

Investigation of X-ray induced radiation damage at the Si-SiO2 interface of silicon sensors for the European XFEL

, 2012
Experiments at the European X-ray Free Electron Laser (XFEL) require silicon pixel sensors which can withstand X-ray doses up to 1 GGy. For the investigation of X-ray radiation damage up to these high doses, MOS capacitors and gate-controlled diodes ...
Fretwurst, Eckhart, Klanner, Robert, Pintilie, Ioana, Schwandt, Joern, Turcato, Monica, Zhang, Jiaguo   +5 more
core   +1 more source

Damage‐limited resolution for X‐ray and electron microscopy of organic specimens

Acta Crystallographica Section D, Volume 82, Issue 5, Page 471-483, May 2026.
Analytical expressions for the damage‐limited resolution are developed and applied to X‐ray and electron imaging of beam‐sensitive specimens. The findings will guide future microscopy and instrument design.Analytical expressions for the damage‐limited resolution (DLR) are developed and applied to X‐ray and electron imaging of beam‐sensitive specimens ...
Ray F. Egerton, Colin Nave
wiley   +1 more source

Diamond sensors for hard X-ray energy and position resolving measurements at the European XFEL

Journal of Synchrotron Radiation
The diagnostics of X-ray beam properties has a critical importance at the European X-ray Free-Electron Laser facility. Besides existing diagnostic components, utilization of a diamond sensor was proposed to achieve radiation-hard, non-invasive beam ...
Tuba Çonka Yıldız, Wolfgang Freund, Jia Liu, Matthias Schreck, Dmitry Khakhulin, Hazem Yousef, Christopher Milne, Jan Grünert   +7 more
doaj   +1 more source

Struktureller Mechanismus eines Aktivitäts‐Photoschalters am β2‐adrenergen Rezeptor

Angewandte Chemie, Volume 138, Issue 18, 27 April 2026.
Zeitaufgelöste Strukturen aus Messungen an Röntgen‐Freie‐Elektronen‐Lasern in Kombination mit zellulären Assays zeigen, wie der photoschaltbare β‐Blocker Photoazolol‐1 als Wirksamkeits‐Photoschalter der Funktion des β2‐adrenergen Rezeptor wirkt. Die lichtinduzierte Neupositionierung des Liganden verschiebt die Aktivität von inversem Agonistimus hin zu ...
Robin Stipp, Quentin Bertrand, Matilde Trabuco, Anna Duran‐Corbera, Maria Tindara Ignazzitto, Hannah Glover, Fabienne Stierli, Juanlo Catena, Melissa Carrillo, Sina Hartmann, Hans‐Peter Seidel, Matthias Mulder, Thomas Mason, Yasushi Kondo, Maximillian Wranik, Martin Appleby, Christoph Sager, Raymond Sierra, Gregory Gate, Pamela Schleissner, Xinxin Cheng, Tobias Weinert, Robert Cheng, Sandra Mous, John H. Beale, Michal Kepa, Amadeu Llebaria, Michael Hennig, Xavier Rovira, Joerg Standfuss   +29 more
wiley   +1 more source

Calculation of effective pump dose in X-ray-pump/X-ray-probe experiments

Journal of Synchrotron Radiation
In pump–probe experiments on solid materials performed within ultrafast X-ray science, the energy deposited by an X-ray pump pulse in the sample has a non-uniform spatial distribution.
Sebastião Antunes, Michal Stransky, Victor Tkachenko, Ichiro Inoue, Philip Heimann, Konrad J. Kapcia, Beata Ziaja   +6 more
doaj   +1 more source

European XFEL Status

, 2017
Future Circular Collider Week 2017, FCC Week 2017, Berlin, DESY, Germany, 29 May 2017 - 2 Jun ...
Weise, Hans, Decking, Winfried
openaire   +2 more sources

Structural Mechanism of an Efficacy Photoswitch Targeting the β2‐adrenergic Receptor

Angewandte Chemie International Edition, Volume 65, Issue 18, 27 April 2026.
Time‐resolved structures from x‐ray free‐electron laser measurements combined with cellular assays demonstrate how the photoswitchable β‐blocker photoazolol‐1 acts as an efficacy switch of β2‐adrenergic receptor function. Light‐induced ligand repositioning shifts activity from inverse agonism toward neutral antagonism by altering local helical ...
Robin Stipp, Quentin Bertrand, Matilde Trabuco, Anna Duran‐Corbera, Maria Tindara Ignazzitto, Hannah Glover, Fabienne Stierli, Juanlo Catena, Melissa Carrillo, Sina Hartmann, Hans‐Peter Seidel, Matthias Mulder, Thomas Mason, Yasushi Kondo, Maximillian Wranik, Martin Appleby, Christoph Sager, Raymond Sierra, Gregory Gate, Pamela Schleissner, Xinxin Cheng, Tobias Weinert, Robert Cheng, Sandra Mous, John H. Beale, Michal Kepa, Amadeu Llebaria, Michael Hennig, Xavier Rovira, Joerg Standfuss   +29 more
wiley   +1 more source

Perspectives of Imaging of Single Protein Molecules with the Present Design of the European XFEL. - Part I - X-ray Source, Beamlime Optics and Instrument Simulations

, 2014
The Single Particles, Clusters and Biomolecules (SPB) instrument at the European XFEL is located behind the SASE1 undulator, and aims to support imaging and structure determination of biological specimen between about 0.1 micrometer and 1 micrometer size.
Geloni, Gianluca, Kocharyan, Vitali, Saldin, Evgeni, Serkez, Svitozar, Yefanov, Oleksandr, Zagorodnov, Igor   +5 more
core  

Study of X-ray Radiation Damage in Silicon Sensors

, 2011
The European X-ray Free Electron Laser (XFEL) will deliver 30,000 fully coherent, high brilliance X-ray pulses per second each with a duration below 100 fs.
E Fretwurst, E.H. Nicollian, H Perrey, H. Perrey, I Pintilie, J Schwandt, J Zhang, J. Schwandt, J. Zhang ., R Klanner, T Poehlsen   +10 more
core   +1 more source