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50th anniversary of the Stanford SSRL synchrotron radiation and protein crystallography initiative [PDF]

open access: yesJournal of Synchrotron Radiation
We provide a historical introduction spanning the past 50 years of synchrotron radiation protein crystallography. We then provide a resume of current trends.
John R. Helliwell   +2 more
doaj   +3 more sources

The Single-Particle, Clusters and Biomolecules and Serial Femtosecond Crystallography instrument of the European X-ray Free-Electron Laser: Interaction Region Downstream at atmospheric pressure (IRD) [PDF]

open access: yesJournal of Synchrotron Radiation
The Single-Particle, Clusters and Biomolecules and Serial Femtosecond Crystallography (SPB/SFX) scientific instrument at the European X-Ray Free-Electron Laser (EuXFEL) became operational with user experiments in September 2017. The unique properties and
Adam Round   +44 more
doaj   +3 more sources

The new XFELs [PDF]

open access: yesNature Methods, 2018
New X-ray free-electron (XFEL) facilities will broaden access to this technology, facilitate methods development, and push boundaries in structural biology.
Allison Doerr
openaire   +2 more sources

Thinner than a knife's edge: 3D-printed liquid sheet jet technology for solution phase XFEL experiments [PDF]

open access: yesIUCrJ, 2023
In this commentary, we explore the pioneering implementation of 3D-printed thin liquid sheet devices for advanced X-ray scattering and spectroscopy experiments at high-repetition rate XFELs.
Martin Trebbin
doaj   +2 more sources

High-quality ultra-fast total scattering and pair distribution function data using an X-ray free-electron laser [PDF]

open access: yesIUCrJ
High-quality total scattering data, a key tool for understanding atomic-scale structure in disordered materials, require stable instrumentation and access to high momentum transfers. This is now routine at dedicated synchrotron instrumentation using high-
Adam F. Sapnik   +50 more
doaj   +2 more sources

Coaxial helium electrospray for single-particle imaging at X-ray free electron lasers [PDF]

open access: yesJournal of Synchrotron Radiation
Single-particle imaging at X-ray free-electron lasers relies on suitable sample injection of nanoscale macromolecules and particles into the gas phase at room temperature.
Safi Rafie-Zinedine   +3 more
doaj   +2 more sources

XFELs for structure and dynamics in biology

open access: yesIUCrJ, 2017
The development and application of the free-electron X-ray laser (XFEL) to structure and dynamics in biology since its inception in 2009 are reviewed. The research opportunities which result from the ability to outrun most radiation-damage effects are ...
J. C. H. Spence
doaj   +2 more sources

High-resolution in situ characterization of laser powder bed fusion via transmission X-ray microscopy at X-ray free-electron lasers [PDF]

open access: yesJournal of Synchrotron Radiation
In this work, we describe the instrumentation used to perform the first operando transmission X-ray microscopy (TXM) and simultaneous X-ray diffraction of laser melting simulating laser powder bed fusion on the XCS instrument at the Linac Coherent Light ...
Zane Taylor   +33 more
doaj   +2 more sources

A comparative review of time-resolved x-ray and electron scattering to probe structural dynamics. [PDF]

open access: yesStruct Dyn
The structure of molecules, particularly the dynamic changes in structure, plays an essential role in understanding physical and chemical phenomena. Time-resolved (TR) scattering techniques serve as crucial experimental tools for studying structural ...
Lee Y, Oang KY, Kim D, Ihee H.
europepmc   +2 more sources

Room temperature X-ray absorption spectroscopy of metalloenzymes with drop-on-demand sample delivery at XFELs

open access: yesPure and applied chemistry. Chimie pure et appliquee, 2023
X-ray crystallography and X-ray spectroscopy using X-ray free electron lasers plays an important role in understanding the interplay of structural changes in the protein and the chemical changes at the metal active site of metalloenzymes through their ...
I. Bogacz   +16 more
semanticscholar   +1 more source

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