Crystal structure of CmABCB1 multi-drug exporter in lipidic mesophase revealed by LCP-SFX
CmABCB1 is a Cyanidioschyzon merolae homolog of human ABCB1, a well known ATP-binding cassette (ABC) transporter responsible for multi-drug resistance in various cancers.
Dongqing Pan +11 more
doaj +1 more source
FAST-XPD: XFEL photon pulses database for modeling XFEL experiments [PDF]
Knowledge of different properties of the radiation from X-ray FEL is very important for planning experiments. An understanding of such properties can come from start-to-end simulations of experiments: modern FEL simulation allows to reliably predict the output radiation pulses from X-ray FEL.
Manetti, Maurizio +7 more
openaire +2 more sources
A superradiant THz undulator source for XFELs [PDF]
The generation of frequency-tunable, narrow-bandwidth and carrier-envelope-phase stable THz pulses with fields in the MV/cm regime that can be appropriately timed to the femtosecond X-ray pulses from free-electron-lasers is of highest scientific interest.
T. Tanikawa +7 more
semanticscholar +2 more sources
Gold Standard for macromolecular crystallography diffraction data
Macromolecular crystallography (MX) is the dominant means of determining the three-dimensional structures of biological macromolecules. Over the last few decades, most MX data have been collected at synchrotron beamlines using a large number of different
Herbert J. Bernstein +11 more
doaj +1 more source
Artificial intelligence for online characterization of ultrashort X-ray free-electron laser pulses
X-ray free-electron lasers (XFELs) as the world’s brightest light sources provide ultrashort X-ray pulses with a duration typically in the order of femtoseconds.
Kristina Dingel +13 more
doaj +1 more source
Temporal pulse shaping aspects of refractive X-ray lenses. [PDF]
This work investigates the temporal effects of refractive X‐ray lenses on ultra‐short pulses from X‐ray free‐electron lasers. Using both a full Fresnel theory model and a simplified ray‐tracing approach, the paper analyzes the pulse elongation and spatio‐temporal distortions introduced by these focusing optics.Refractive X‐ray lenses are frequently ...
Trost F, Bielecki J, Bean R.
europepmc +2 more sources
Single-particle imaging by x-ray free-electron lasers—How many snapshots are needed?
X-ray free-electron lasers (XFELs) open the possibility of obtaining diffraction information from a single biological macromolecule. This is because XFELs can generate extremely intense x-ray pulses that are so short that diffraction data can be ...
I. Poudyal, M. Schmidt, P. Schwander
doaj +1 more source
3D-printed sheet jet for stable megahertz liquid sample delivery at X-ray free-electron lasers
X-ray free-electron lasers (XFELs) can probe chemical and biological reactions as they unfold with unprecedented spatial and temporal resolution. A principal challenge in this pursuit involves the delivery of samples to the X-ray interaction point in ...
Patrick E. Konold +27 more
doaj +1 more source
XFELs: cutting edge X-ray light for chemical and material sciences.
Kiyotaka Asakura, Kelly J. Gaffney, Christopher Milne, and Makina Yabashi introduce the PCCP themed issue on X-ray free-electron lasers (XFELs).
K. Asakura +3 more
semanticscholar +1 more source
Advances in long-wavelength native phasing at X-ray free-electron lasers
Long-wavelength pulses from the Swiss X-ray free-electron laser (XFEL) have been used for de novo protein structure determination by native single-wavelength anomalous diffraction (native-SAD) phasing of serial femtosecond crystallography (SFX) data.
Karol Nass +35 more
doaj +1 more source

