Results 111 to 120 of about 53,903 (231)

Bombyx mori‐Hosted Cordyceps militaris Polysaccharides: Structural Characterization and Antibacterial Activity of Native and Sulfated Derivatives

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
This study demonstrates that sulfation enhances the antibacterial activity of Bombyx mori‐hosted Cordyceps militaris polysaccharides. Activity correlated positively with sulfate content and negative charge density, with the highest substituted derivative exhibiting optimal efficacy.
Jingchun Yang   +6 more
wiley   +1 more source

Antibacterial and Immunomodulatory Activities of a Natural Polysaccharide Against Staphylococcus aureus Infection

open access: yesFood Science &Nutrition, Volume 14, Issue 10, October 2026.
Polysaccharides from Polygonatum kingianum (PKP) were extracted with ethanol and hot distilled water, followed by centrifugation and drying. In vitro, PKP inhibited both E. coli and Staphylococcus aureus in a concentration‐dependent manner, with stronger activity against the Gram‐positive S. aureus (89.8% at 400 mg/mL) than against E.
Xu‐Chen Xia   +6 more
wiley   +1 more source

Gastrodia elata Polysaccharide Attenuates Aging by Modulating Oxidative Stress, Inflammation, and Gut Microbiota

open access: yesFood Science &Nutrition, Volume 14, Issue 10, October 2026.
Gastrodia elata polysaccharide (GEP) alleviates aging in mice by activating the Nrf2/Keap1 antioxidant signaling, inhibiting the TLR4/NF‐κB‐driven neuroinflammation, remodeling gut microbiota, and restoring intestinal‐barrier integrity. Synergistic regulation of oxidation, inflammation, and gut homeostasis underpins its anti‐aging potential for ...
Huihuang Shi   +5 more
wiley   +1 more source

Interrogating the Escherichia coli Epitranscriptome Via CRISPR Interference and Nanopore Native RNA Sequencing

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
Epitranscriptomics is understudied in bacteria but has the ability to modulate antimicrobial resistance, virulence and pathogenicity. Pitt et al. implement two cutting‐edge techniques: CRISPR interference and Nanopore direct RNA sequencing along with functional assays to study RNA modifications in Escherichia coli.
Miranda E. Pitt   +8 more
wiley   +1 more source

Best practices for cryo‐trapping time‐resolved crystallography with the Spitrobot crystal plunger

open access: yesProtein Science, Volume 35, Issue 10, October 2026.
Abstract Capturing meta‐stable conformations of enzymes and ligand complexes demands structural snapshots beyond static crystal structures. While time‐resolved serial crystallography at room temperature offers a time‐resolution down to the femto‐second domain, it requires large amounts of micro crystals, specialized beamlines, and considerable ...
Robert Bosman   +7 more
wiley   +1 more source

Coupled Mechano‐Chemical Pretreatment of Poplar Wood to Enhance Enzymatic Hydrolysis for Low‐Cost Biorefinery

open access: yesRare Metals, Volume 45, Issue 10, October 2026.
ABSTRACT Common methods of lignocellulose pretreatment (such as acid method, alkali method, and organic solvent method) have been severely restricted in their development due to issues such as harsh reaction conditions, high cost of reagents, and heavy environmental burden.
Weirong Li   +9 more
wiley   +1 more source

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