Results 221 to 230 of about 60,617 (307)

Dual Roles of Ubiquitin-Specific Peptidase 10 (USP10) in Cancer. [PDF]

Cells
Zhai Y, Zhou L, Zhao M, Lin Q.
europepmc   +1 more source

Hybrid Multiphoton Lithography Scaffolds for Nanoscale Mechanobiological Assessment in Microscale Bone Models

Small, EarlyView.
This work presents a 3D hybrid tissue scaffold inspired by bone, incorporating collagen, fabricated using multiphoton lithography. The mechanical properties of collagen are tunable, and biodegradation allows for time‐dependent changes in geometry. The results demonstrate enhanced osteogenic differentiation of stem cells in our hybrid scaffolds.
Christoph Naderer, Eleni Priglinger, Martina Ramsauer, Cornelia Bergmayr, Tobias Gotterbarm, Sofia Danilchenko, Dmitry Sivun, Jaroslaw Jacak   +7 more
wiley   +1 more source

PI3K regulates TAZ/YAP and mTORC1 axes that can be synergistically targeted. [PDF]

JCI Insight
Garcia KC, Khan AA, Ghosh K, Sinha S, Scalora N, DeWane G, Fullenkamp C, Merritt N, Drebot Y, Yu SY, Leidinger M, Henry MD, Breheny PJ, Chimenti MS, Tanas MR.   +14 more
europepmc   +1 more source

Molecular Mechanisms of FAT Atypical Cadherin 1 (FAT1), the Hippo Pathway, and the Yes-Associated Protein (YAP) Signaling Pathways in Some Cancers [PDF]

Roland Osei Saahene, Precious Barnes, Du-Bois Asante, Sylvester Ackah Famieh, Elvis Agbo   +4 more
openalex   +1 more source

Shape‐Memory Collagen/Silk‐Fibroin Scaffold for Dura Sealing and Skull Base Regeneration

Small, EarlyView.
ABSTRACT When a skull base defect occurs, reconstruction is typically performed using a variety of autologous grafts, flaps, or synthetic materials. Failure to achieve appropriate management and closure can lead to serious consequences, such as cerebrospinal fluid (CSF) leakage and subsequent meningitis.
SooJung Chae, Donghyeok Kim, Dongyun Kim, JaeYoon Lee, Sang Duk Hong, GeunHyung Kim   +5 more
wiley   +1 more source

Liquid biopsy in genitourinary oncology: Current clinical applications and future prospects across prostate, bladder, and renal cancers

UroPrecision, EarlyView.
Abstract Liquid biopsy has emerged as a transformative approach in oncology, providing minimally invasive access to tumor‐derived biomarkers with applications across diagnosis, prognosis, therapeutic guidance, and disease monitoring. This literature review synthesizes evidence from 125 studies evaluating circulating tumor DNA, circulating tumor cells ...
Kirolos Eskandar
wiley   +1 more source

Crosstalk of Nemo-Like Kinase (NLK) and Yes-Associated Protein (YAP) Phosphorylation in Endometrial Epithelial Cells. [PDF]

Dev Reprod
Moon S, Lee S, Choi Y.
europepmc   +1 more source

Potential targets for renal cell carcinoma therapy: Mechanistic research and prospects of CAFs in renal cell carcinoma

VIEW, EarlyView.
Cancer‐associated fibroblasts exert intricate mechanisms in the progression and metastasis of renal cell carcinoma. Existing studies have validated the relevant mechanisms of three signaling pathways, which hold promising potential as novel therapeutic targets.
Ruiqiang Sun, Jiankun Zhang, Meixi Liu, Xiyue Dong, Yuanshan Cui   +4 more
wiley   +1 more source

Synthetic control of implanted engineered liver tissue growth. [PDF]

Sci Adv
Stoddard AE, Kumar V, Tzouanas CN, Hui V, Li J, Jain A, Farrell A, Bhatia SN, Chen CS.   +8 more
europepmc   +1 more source

Modeling the lung‒brain axis in critical illness: Multifactorial crosstalk through organoids and organ‐on‐a‐chip system

VIEW, EarlyView.
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang, Ting Wang, Mengying Yao, Longxiang Su, Lixin Xie, Pan Pan   +5 more
wiley   +1 more source