Results 211 to 220 of about 23,621 (250)

YAP1 Enhances Mesenchymal-Type Gene Expression in Human Adrenergic-Type Neuroblastoma Cells. [PDF]

Cancers (Basel)
Ludwig M, Ahrens K, Winkler A, Wünschel J, Ruka P, Lodrini M, Hertwig F, Castelli S, Thole-Kliesch TM, Hollander JF, Fuchs S, Künkele A, Jens M, Mamlouk S, Warmann SW, Astrahantseff K, Eggert A, Schulte JH, Szymansky A, Deubzer HE.   +19 more
europepmc   +1 more source

Expression of YAP1 in aggressive thyroid cancer

Endocrine, 2017
The Hippo signal transduction pathway plays a crucial role in the control of cellular proliferation, so that its deregulation is believed to be involved in neoplastic transformation [1, 2]. A wide array of human cancers show a down-regulation of Hippo pathway, resulting in the activation of the co-transcription factors Yes-associated protein (YAP1) as ...
Celano, Marilena, Mignogna, Chiara, ROSIGNOLO, FRANCESCA, SPONZIELLO, Marialuisa, Iannone, Michelangelo, Lepore, Saverio Massimo, Lombardo, Giovanni Enrico, Maggisano, Valentina, VERRIENTI, Antonella, Bulotta, Stefania, DURANTE, COSIMO, Di Loreto, Carla, Damante, Giuseppe, Russo, Diego   +13 more
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YAP1::MAML2, YAP1::NUTM1, and RNF13::PAK2 rearrangements in trichoblastomas and adnexal tumors with panfollicular differentiation: expanding the spectrum of YAP1/PAK-fused skin adnexal tumors

Virchows Archiv
In 2019, YAP1::MAML2 and YAP1::NUTM1 rearrangements were demonstrated in the majority of poromas and in porocarcinomas. Recently, our group demonstrated recurrent fusions of PAK (p21 (RAC1) activated kinase) 1/2/3 genes in a subset of poromas and porocarcinomas frequently harboring hair follicle and sebaceous differentiation.
Kervarrec, Thibault, Macagno, Nicolas, Houlier, Aurelie, Pissaloux, Daniel, Thamphya, Brice, Louveau, Baptiste, Mourah, Samia, Mancini, Maxence, Kazakov, Dmitry, Harnisch, Kim, Tirode, Franck, Cazzato, Gerardo, Sohier, Pierre, de la Fouchardière, Arnaud, Battistella, Maxime, Calonje, Eduardo   +15 more
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YAP1 mediates gastric adenocarcinoma peritoneal metastases that are attenuated by YAP1 inhibition

Gut, 2020
Objective Peritoneal carcinomatosis (PC; malignant ascites or implants) occurs in approximately 45% of advanced gastric adenocarcinoma (GAC) patients and associated with a poor survival. The molecular events leading to PC are unknown.
Jaffer A Ajani, Yan Xu, Longfei Huo, Ruiping Wang, Yuan Li, Ying Wang, Melissa Pool Pizzi, Ailing Scott, Kazuto Harada, Lang Ma, Xiaodan Yao, Jiankang Jin, Wei Zhao, Xiaochuan Dong, Brian D Badgwell, Namita Shanbhag, Ghia Tatlonghari, Jeannelyn Santiano Estrella, Sinchita Roy-Chowdhuri, Makoto Kobayashi, Jody V Vykoukal, Samir M Hanash, George Adrian Calin, Guang Peng, Ju-Seog Lee, Randy L Johnson, Zhenning Wang, Linghua Wang, Shumei Song   +28 more
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Loss of expression of YAP1 C-terminus as an ancillary marker for epithelioid hemangioendothelioma variant with YAP1-TFE3 fusion and other YAP1-related vascular neoplasms

Modern Pathology, 2021
Epithelioid hemangioendothelioma (EHE) with YAP1-TFE3 fusion is a recently characterized distinctive variant of EHE that accounts for a small subset (
William J. Anderson, Christopher D.M. Fletcher, Jason L. Hornick   +2 more
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C11orf95-RELA, YAP1-MAMLD1, and YAP1-FAM118B Fusion Negative Anaplastic Ependymoma with Lipogenic Differentiation

Neurology India, 2023
Lipogenic differentiation in ependymoma is an infrequent occurrence with very few reported cases. The grading was done solely based on the histomorphology and molecular subtyping was not described in such ependymomas. New molecular classification divided ependymomas in nine different subgroups, of which supratentorial location
Shilpy, Jha, Prit Benny, Mulgulwar, Mehar Chand, Sharma, Suvendu, Purkait, Ashis, Pattnaik, Mukund Namdev, Sable   +5 more
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Targeting YAP1 ameliorates progesterone resistance in endometriosis

Human Reproduction, 2023
Abstract STUDY QUESTION Does YAP1 inhibition alleviate progesterone resistance in endometriosis? SUMMARY ANSWER YAP1 inhibition reduces progesterone resistance in vitro and in vivo ...
Shih-Chieh Lin, Wan-Ning Li, Shin-Chih Lin, Haun-Tzu Hou, Ya-Chuan Tsai, Tin-Chien Lin, Meng-Hsing Wu, Shaw-Jenq Tsai   +7 more
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