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Neurology India, 2023
Lipogenic differentiation in ependymoma is an infrequent occurrence with very few reported cases. The grading was done solely based on the histomorphology and molecular subtyping was not described in such ependymomas. New molecular classification divided ependymomas in nine different subgroups, of which supratentorial location
Shilpy, Jha +5 more
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Lipogenic differentiation in ependymoma is an infrequent occurrence with very few reported cases. The grading was done solely based on the histomorphology and molecular subtyping was not described in such ependymomas. New molecular classification divided ependymomas in nine different subgroups, of which supratentorial location
Shilpy, Jha +5 more
openaire +2 more sources
Antisense Oligos May Hit “Undruggable” YAP1
Cancer Discovery, 2021Abstract An antisense oligonucleotide that targets the Hippo pathway protein YAP1, long thought “undruggable,” has shown preclinical promise and is under evaluation in a phase I trial.
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YAP1 Is a Crucial Nexus in the Tumor Microenvironment
Current Medical ScienceYes-associated protein-1 (YAP1) is an oncogenic effector of the Hippo signaling pathway, activated in several cancer types, and has been extensively studied in cancer progression and therapy. A large number of studies have established the importance of YAP1 in promoting cell-autonomous functions, including uncontrolled growth, sustained proliferative ...
Raghavan, Narasimhan +4 more
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A novel YAP1-MAML2 fusion in an adult supra-tentorial ependymoma, YAP1-fused
Brain Tumor Pathology, 2022Tauziède-Espariat, Arnault +12 more
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Nuclear condensates in YAP1-driven ependymoma
Nature Cell Biology, 2023Mahsa Shahidi Dadras, Howard A. Fine
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YAP1 and WWTR1 are required for murine pregnancy initiation
ReproductionIn brief The HIPPO signaling effectors YAP1 and WWTR1 are required for murine pregnancy initiation, and mutation of these factors compromises the decidualization response and overall pregnancy success.
Genna E Moldovan +8 more
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YAP1 and its fusion proteins in cancer initiation, progression and therapeutic resistance
Developmental Biology, 2021Frank Szulzewsky +2 more
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Utility of YAP1 and NUT immunohistochemistry in the diagnosis of porocarcinoma
Journal of Cutaneous Pathology, 2021, Jason Hornick
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